Results 51 to 60 of about 1,357,671 (290)

Using online primary sources to foster historical thinking [PDF]

open access: yes, 2016
This paper describes an ongoing initiative to enhance learner digital literacies by fostering historical thinking using digitized primary sources.
Brunton, James, Farrell, Orna
core  

Moderate emissions grandfathering [PDF]

open access: yes, 2014
Emissions grandfathering holds that a history of emissions strengthens an agent’s claim for future emission entitlements. Though grandfathering appears to have been influential in actual emission control frameworks, it is rarely taken seriously by ...
Knight, Carl
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Teaching historical thinking in practice: a study of US history teachers’ views on using primary sources in AP and IB history lessons

open access: yesHistory Education Research Journal, 2022
Analysis of primary sources has been recognised to have a significant impact on the development of students’ historical thinking. This study explored US history teachers’ attitudes and practices to using primary sources by interviewing six history ...
doaj   +2 more sources

Feminism, Intersectionality, and Gender Category: Essential Contributions for Historical Thinking Development

open access: yesFrontiers in Education, 2022
The following article inquires how introducing the gender category, feminism theories, and intersectionality into social sciences education, especially regarding historical thinking development, could be key for the construction of a more critical and ...
María del Consuelo Díez-Bedmar
doaj   +1 more source

Project strategies of political thought: meta-scientific dominants [PDF]

open access: yes, 2015
This paper deals with the problem of philosophical and scientific (epistemological) reflection of the value assumptions in political thinking. The authors of the paper use the concept of civic consciousness to demonstrate the relationship of historical ...
Olkhov, P. A., Polukhin, O. N.
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Henry David Thoreau in Context [PDF]

open access: yes, 2017
Well known for his contrarian and solitary posture, Henry David Thoreau was nonetheless deeply responsive to the world around him. Tracing a wide range of geographic, intellectual, cultural, political, and scientific contexts, this volume brings together
James S. Finley
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Home - About - Disclaimer - Privacy