Results 111 to 120 of about 5,700,334 (377)
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Philosophy of Computer Science: An Introductory Course [PDF]
, 2005 There are many branches of philosophy called “the philosophy of X,” where X = disciplines ranging from history to physics. The philosophy of artificial intelligence has a long history, and there are many courses and texts with that title.
Rapaport, William J.
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Hume's Natural Philosophy and Philosophy of Physical Science [PDF]
, 2020 This book contextualizes David Hume's philosophy of physical science, exploring both Hume's background in the history of early modern natural philosophy and its subsequent impact on the scientific ...
Slavov, Matias
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The Hummingbird Collection of the Natural History and Science Museum of the University of Porto (MHNC-UP), Portugal. [PDF]
Biodivers Data J, 2021 Lopes RJ +4 more
europepmc +1 more source
Medical Library Association Handbook of Medical Library Practice with a Bibliography of the Reference Works and Histories in Medicine and the Allied Sciences [PDF]
, 1956 openalex +1 more source
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Arguments in a Sartorial Mode, or the Asymmetries of History and Philosophy of Science [PDF]
, 1992 History of science and philosophy of science are not perfectly complementary disciplines. Several important asymmetries govern their relationship. These asymmetries, concerning levels of analysis, evidence, theories, writing, and training show that to be
Richards, Robert J.
core
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source