Results 51 to 60 of about 2,017,079 (263)

Design and research of soft-body cavity-type detonation drivers

open access: yesiScience, 2023
Summary: According to the high-energy-density movement characteristics of animals during jumping, soft-body cavity-type detonation driver that combines the explosive chemical reaction mechanism of hydrogen and oxygen is designed, in order to control the ...
Yitao Pan   +4 more
doaj   +1 more source

RWU Professor Examines Frequent Storm Activity [PDF]

open access: yes, 2017
As intense, consecutive storms continue to hit the country, signaling a change in hurricanes, environmental science expert weighs ...
Wilder, Justin
core   +1 more source

Performance studies of the Belle II Silicon Vertex Detector with data taken at the DESY test beam in April 2016 [PDF]

open access: yes, 2017
Belle II is a multipurpose detector currently under construction which will be operated at the next generation B-factory SuberKEKB in Japan. Its main devices for the vertex reconstruction are the Silicon Vertex Detector (SVD) and the Pixel Detector (PXD).
Adamczyk, K.   +107 more
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Reframing innovation and technology for healthcare: A commitment to the human experience

open access: yesPatient Experience Journal, 2019
This latest special issue of Patient Experience Journal focuses on the role of technology and innovation in patient experience. The articles included in this issue help us think about the ideas of innovation and health information technology (HIT) in ...
Jason Wolf
doaj  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Health information technology: A key ingredient of the patient experience

open access: yesPatient Experience Journal, 2015
In this exploration to understand the linkages of health information technology (HIT) and patient experience, a comprehensive literature search was conducted using the key words, “information technology, HIT, patient experience, patient satisfaction, and
Matthew Werder
doaj  

Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling

open access: yesNature Communications, 2022
aGPCRs play key roles in multiple physiological processes. Here the authors report cryo-EM structures of GPR110 in complexes with Gq, Gs, Gi, G12 and G13 protein to reveal a detailed mechanism of aGPCR activation via the tethered stalk peptide and ...
Xinyan Zhu   +11 more
doaj   +1 more source

Did Boomerang hit MOND?

open access: yes, 2005
Purely baryonic dark matter dominated models like MOND based on modification of Newtonian gravity have been successfully in reproducing some dynamical properties of galaxies.
Melchiorri, Alessandro   +2 more
core   +1 more source

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