Results 101 to 110 of about 24,860,034 (345)
Prevalence of HIV Transmitted Drug Resistance in Nanjing from 2018 to 2021
Yifan Su,1 Mingxue Qi,1 Mingli Zhong,2 Nawei Yu,1 Chen Chen,1 Zi Ye,1 Cong Cheng,1 Zhiliang Hu,1 Hongying Zhang,3 Hongxia Wei1 1Department of Infectious Disease, The Second Hospital of Nanjing Affiliated to Nanjing University of Chinese Medicine, Nanjing,
Su Y+9 more
doaj
Interaction of silver nanoparticles with HIV-1
The interaction of nanoparticles with biomolecules and microorganisms is an expanding field of research. Within this field, an area that has been largely unexplored is the interaction of metal nanoparticles with viruses. In this work, we demonstrate that
J. L. Elechiguerra+6 more
semanticscholar +1 more source
Genetic Engineering Methods in Primary T Cells
Primary T cells can be engineered to confer them with novel therapeutic functions, allowing them to treat a variety of conditions. Genetic engineering can be either stable or transient, aiming to either express or inhibit a target gene. This review discusses the various genetic engineering tools available as well as their characteristics and ...
Anthony Youssef, Hui‐Shan Li
wiley +1 more source
Alexander O. Pasternak+4 more
doaj +1 more source
Combination therapy with anti-HIV-1 antibodies maintains viral suppression
Individuals infected with HIV-1 require lifelong antiretroviral therapy, because interruption of treatment leads to rapid rebound viraemia. Here we report on a phase 1b clinical trial in which a combination of 3BNC117 and 10-1074, two potent monoclonal ...
Pilar Mendoza+35 more
semanticscholar +1 more source
Computational fluid dynamics analyses assess the upstream locomotion performance of anisotropic microrollers with varying height‐to‐width ratios. Observing their successful upstream locomotion in veins, their performance in hepatic circulation is investigated for treating primary liver cancer.
Burak Arslan+8 more
wiley +1 more source
HIV-1 GP120-mediated immune suppression and lymphocyte destruction in the absence of viral infection. [PDF]
Kent J. Weinhold+5 more
openalex +1 more source
HIV-1 virion assembly at the plasma membrane requires the selective recruitment of the viral RNA genome into nascent viral particles while cellular transcripts are excluded. Kutluay et al. now demonstrate that this is a two-step process in which Gag binds sequentially to different sites on the viral genome.
openaire +3 more sources
USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang+13 more
wiley +1 more source
Generating Vectors for the Lattice Structures of Tubular and Conical Viral Capsids
Retrovirus capsid is a fullerene-like lattice consisting of capsid protein hexamers and pentamers. Mathematical models for the lattice structure help understand the underlying biological mechanisms in the formation of viral capsids.
Sadre-Marandi Farrah+3 more
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