Results 11 to 20 of about 25,225,361 (379)
Breast Milk from Tanzanian Women has Divergent Effects on Cell-Free and Cell-Associated HIV-1 Infection in Vitro. [PDF]
, 2012 Transmission of HIV-1 during breastfeeding is a significant source of new pediatric infections in sub-Saharan Africa. Breast milk from HIV-positive mothers contains both cell-free and cell-associated virus; however, the impact of breast milk on HIV-1 ...
Alexandra L. Howell +7 more
core +26 more sources
Retrovirology, 2013 Background The HIV virus hijacks cellular machineries to replicate. Post-translational modifications, like acetylation, phosphorylation or ubiquitination, are no exception. We are interested in studying the interplay between HIV and the SUMOylation pathway.
Beauclair, Guillaume +2 more
openaire +3 more sources
mBio, 2021 Knowing the mechanisms that govern the persistence of infected CD4+ subpopulations could help us to design new therapies to cure HIV-1 infection. We evaluated the simultaneous distribution of the HIV-1 reservoir in 13 CD4+ subpopulations from 14 HIV-1 ...
Cristina Gálvez +6 more
doaj +1 more source
Retrovirology, 2005 Abstract New York City health officials announced on February 11, 2005 that a patient rapidly developed full-blown AIDS shortly after being diagnosed with a rare, drug-resistant strain of HIV-1. The New York City Department of Health issued an alert to all hospitals and doctors and a press conference was held to announce the emergence of an ...
Berkhout, B. +2 more
openaire +5 more sources
HIV-1: To Splice or Not to Splice, That Is the Question
Viruses, 2021 The transcription of the HIV-1 provirus results in only one type of transcript—full length genomic RNA. To make the mRNA transcripts for the accessory proteins Tat and Rev, the genomic RNA must completely splice.
Ann Emery, Ronald Swanstrom
doaj +1 more source
Cell, 2008 In 1981, the acquired immunodeficiency syndrome (AIDS) appeared insidiously and mystified doctors and scientists alike. No one could have predicted then that it would become, arguably, the worst plague in human history. Today, 33 million persons are living with infection by the human immunodeficiency virus type 1 (HIV-1), the causative agent of AIDS ...
Paul D. Bieniasz, David D. Ho
openaire +2 more sources
HIV-1 transmission and acute HIV-1 infection [PDF]
British Medical Bulletin, 2001 An understanding of the central events in the transmission of HIV-1 infection is critical to the development of effective strategies to prevent infection. Although the main routes of transmission have been known for some time, surprisingly little is known about the factors that influence the likelihood of transmitting or acquiring HIV-1 infection. Once
Hansasuta, P, Rowland-Jones, S
openaire +3 more sources
BMJ Open, 2023 Objectives To describe the implementation of screening for cryptococcal antigenaemia by point-of-care (POC) serum cryptococcal antigen (CrAg) lateral flow assay, measure the prevalence and factors associated with serum cryptococcal antigenaemia in the ...
Amit Harshana +15 more
doaj +1 more source
HIV-1 Prevention for HIV-1 Serodiscordant Couples [PDF]
Current HIV/AIDS Reports, 2012 A substantial proportion of HIV-1 infected individuals in sub-Saharan Africa are in stable relationships with HIV-1 uninfected partners, and HIV-1 serodiscordant couples thus represent an important target population for HIV-1 prevention. Couple-based HIV-1 testing and counseling facilitates identification of HIV-1 serodiscordant couples, counseling ...
Curran, K +5 more
openaire +2 more sources
Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus. [PDF]
, 2016 HIV-1 entry can be inhibited by soluble peptides from the gp41 heptad repeat-2 (HR2) domain that interfere with formation of the 6-helix bundle during fusion.
DeClercq, Joshua J. +16 more
core +10 more sources