Results 11 to 20 of about 658,368 (320)
A potential biomarker of cognitive impairment: The olfactory dysfunction and its genes expression
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1884-1897, December 2022., 2022 Abstract Objective Accumulation evidence has reported that olfactory impairment may be an essential clinical marker and predictor of mild cognitive impairment or Alzheimer's disease. Method Participants were enrolled in the population‐based, prospective study in Fuxin county, Liaoning province, China between 2019 and 2021.
Jiayi Song +11 more
wiley +1 more source
Targeting the HIV reservoir: chimeric antigen receptor therapy for HIV cure
Chinese Medical Journal, 2023 . Although antiretroviral therapy (ART) can reduce the viral load in the plasma to undetectable levels in human immunodeficiency virus (HIV)-infected individuals, ART alone cannot completely eliminate HIV due to its integration into the host cell genome ...
Shuang Li +6 more
doaj +1 more source
HIV-1 Hijacking of Host ATPases and GTPases That Control Protein Trafficking
Frontiers in Cell and Developmental Biology, 2021 The human immunodeficiency virus (HIV-1) modifies the host cell environment to ensure efficient and sustained viral replication. Key to these processes is the capacity of the virus to hijack ATPases, GTPases and the associated proteins that control ...
Lucas A. Tavares +2 more
doaj +1 more source
Retrovirology, 2018 Background The ability of human immunodeficiency virus type 1 (HIV-1) to form a stable viral reservoir is the major obstacle to an HIV-1 cure and post-transcriptional events contribute to the maintenance of viral latency.
Shringar Rao +4 more
doaj +1 more source
HIV-1 Gag Blocks Selenite-Induced Stress Granule Assembly by Altering the mRNA Cap-Binding Complex
mBio, 2016 Stress granules (SGs) are dynamic accumulations of stalled preinitiation complexes and translational machinery that assemble under stressful conditions.
Alessandro Cinti +3 more
doaj +1 more source
BMC Public Health, 2021 Background The aim of this study was to develop a standardized method to reconstruct persons’ individual viral load (VL) courses to determine viral suppression and duration of viremia for the HIV care continuum in Germany using longitudinal cohort data ...
Daniel Schmidt +8 more
doaj +1 more source
Revista Latino-Americana de Enfermagem, 2000 Esta pesquisa de caráter descritivo insere-se nos pressupostos dos métodos qualitativos de investigação, sendo fundamentada pela Teoria da Crise preconizada por CAPLAN (1966).
Mara Rúbia Ignácio de Freitas +2 more
doaj +1 more source
Chinese Medical Journal, 2023 . Background:. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine can induce a potent cellular and humoral immune response to protect against SARS-CoV-2 infection.
Xiaodong Yang +14 more
doaj +1 more source
Adapting the Stress Response: Viral Subversion of the mTOR Signaling Pathway
Viruses, 2016 The mammalian target of rapamycin (mTOR) is a central regulator of gene expression, translation and various metabolic processes. Multiple extracellular (growth factors) and intracellular (energy status) molecular signals as well as a variety of stressors
Valerie Le Sage +3 more
doaj +1 more source
Mathematical Biosciences and Engineering, 2021 We present the Progression and Transmission of HIV (PATH 4.0), a simulation tool for analyses of cluster detection and intervention strategies.
Sonza Singh +5 more
doaj +1 more source