Results 11 to 20 of about 707,804 (298)
HIV-1 Hijacking of Host ATPases and GTPases That Control Protein Trafficking
Frontiers in Cell and Developmental Biology, 2021 The human immunodeficiency virus (HIV-1) modifies the host cell environment to ensure efficient and sustained viral replication. Key to these processes is the capacity of the virus to hijack ATPases, GTPases and the associated proteins that control ...
Lucas A. Tavares +2 more
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HIV-1 Gag Blocks Selenite-Induced Stress Granule Assembly by Altering the mRNA Cap-Binding Complex
mBio, 2016 Stress granules (SGs) are dynamic accumulations of stalled preinitiation complexes and translational machinery that assemble under stressful conditions.
Alessandro Cinti +3 more
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Revista Latino-Americana de Enfermagem, 2000 Esta pesquisa de caráter descritivo insere-se nos pressupostos dos métodos qualitativos de investigação, sendo fundamentada pela Teoria da Crise preconizada por CAPLAN (1966).
Mara Rúbia Ignácio de Freitas +2 more
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Adapting the Stress Response: Viral Subversion of the mTOR Signaling Pathway
Viruses, 2016 The mammalian target of rapamycin (mTOR) is a central regulator of gene expression, translation and various metabolic processes. Multiple extracellular (growth factors) and intracellular (energy status) molecular signals as well as a variety of stressors
Valerie Le Sage +3 more
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BMC Public Health, 2021 Background The aim of this study was to develop a standardized method to reconstruct persons’ individual viral load (VL) courses to determine viral suppression and duration of viremia for the HIV care continuum in Germany using longitudinal cohort data ...
Daniel Schmidt +8 more
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Chinese Medical Journal, 2023 . Background:. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine can induce a potent cellular and humoral immune response to protect against SARS-CoV-2 infection.
Xiaodong Yang +14 more
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HIV-1 Reverse Transcription [PDF]
, 2014 Reverse transcription is an obligatory step in retrovirus replication in the course of which the retroviral RNA/DNA-dependent DNA polymerase (RT) copies the single-stranded positive sense RNA genome to synthesize the double-stranded viral DNA. At the same time the RT-associated RNaseH activity degrades the genomic RNA template, which has just been ...
Cimarelli, Andrea, Darlix, Jean-Luc
openaire +3 more sources
HIV-1 enhances mTORC1 activity and repositions lysosomes to the periphery by co-opting Rag GTPases
Scientific Reports, 2017 HIV-1 co-opts several host machinery to generate a permissive environment for viral replication and transmission. In this work we reveal how HIV-1 impacts the host translation and intracellular vesicular trafficking machineries for protein synthesis and ...
Alessandro Cinti +8 more
doaj +1 more source
Depicting HIV-1 Transcriptional Mechanisms: A Summary of What We Know
Viruses, 2020 Despite the introduction of combinatory antiretroviral therapy (cART), HIV-1 infection cannot be cured and is still one of the major health issues worldwide. Indeed, as soon as cART is interrupted, a rapid rebound of viremia is observed.
Antoine Dutilleul +2 more
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Mathematical Biosciences and Engineering, 2021 We present the Progression and Transmission of HIV (PATH 4.0), a simulation tool for analyses of cluster detection and intervention strategies.
Sonza Singh +5 more
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