Results 31 to 40 of about 707,804 (298)
Pathogens, 2020 Streptococcus pneumoniae (S. pneumoniae) vaccines have substantially reduced the burden of invasive pneumococcal diseases (IPDs) worldwide. Despite high coverage with S. pneumoniae vaccination, upper-respiratory-tract colonization by S.
Mahlet Lemma +7 more
doaj +1 more source
Nature Reviews Microbiology, 2018 This study used a large cohort of HIV-1 transmission pairs to determine the contribution of viral genetics on the development of neutralizing antibodies.
openaire +2 more sources
HIV-1: maternal prognosis [PDF]
Revista do Hospital das Clínicas, 2004 Profound modifications in the profile of patients are currently being observed within the epidemic context of AIDS, especially with respect to pauperization and feminization of the disease. The population most frequently affected is in the reproductive age, and among adults aged 18 to 24 years, the ratio is 1 man to 1 woman, a phenomenon occurring ...
El Beitune, Patrícia +3 more
openaire +4 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Acta Medica Indonesiana, 2022 Background: The use of complementary and alternative medicine (CAM) is widespread among patients with chronic disease despite lack of supporting evidence for most CAM types.
Evy Yunihastuti +9 more
doaj
Sensor Sensibility—HIV-1 and the Innate Immune Response
Cells, 2020 Innate immunity represents the human immune system’s first line of defense against a pathogenic intruder and is initiated by the recognition of conserved molecular structures known as pathogen-associated molecular patterns (PAMPs) by specialized ...
Xin Yin +6 more
doaj +1 more source
Mother-to-child transmission of HIV-1 and infant mortality in the first six months of life, in the era of Option B Plus combination antiretroviral therapy [PDF]
, 2021 Lynn S. Zijenah +4 more
openalex +1 more source
Cell, 2008 4 to 35 trimersTM Binds cell-surface receptors; mediates virus attachment and entry CD4 CD4 plus CCR5/CXCR4 mediate virion entry; major determinants of viral tropismChemokine receptors (CCR5 and CXCR4)C-type lectin receptors (DC-SIGN, Langerin) Virion capture; viral transmission from dendritic cells to T ...
Swanson, C M, Malim, M H
openaire +2 more sources
Nature Reviews Microbiology, 2006 Genomics is now a core element in the effort to develop a vaccine against HIV-1. Thanks to unprecedented progress in high-throughput genotyping and sequencing, in knowledge about genetic variation in humans, and in evolutionary genomics, it is finally possible to systematically search the genome for common genetic variants that influence the human ...
Amalio, Telenti, David B, Goldstein
openaire +2 more sources
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source