Results 1 to 10 of about 119,863 (250)

Altruism: Scoping review of the literature and future directions for HIV cure-related research [PDF]

Journal of Virus Eradication, 2020
Introduction: The question of what motivates people to participate in research is particularly salient in the HIV field. While participation in HIV research was driven by survival in the 1980’s and early 1990’s, access to novel therapies became the ...
Karine Dubé, Kelly E. Perry, Kushagra Mathur, Megan Lo, Sogol S. Javadi, Hursch Patel, Susanna Concha-Garcia, Jeff Taylor, Andy Kaytes, Lynda Dee, Danielle Campbell, John Kanazawa, David Smith, Sara Gianella, Judith D. Auerbach, Parya Saberi, John A. Sauceda   +16 more
doaj   +8 more sources

Participation in HIV cure-related research: a scoping review of the proxy literature and implications for future research [PDF]

Journal of Virus Eradication, 2015
Objective: To identify the main types of HIV cure-related strategies and examine possible risks (and benefits) associated with participating in HIV cure-related research studies.
Karine Dubé, Catalina Ramirez, Jessica Handibode, Jeffrey Taylor, Asheley Skinner, Sandra Greene, Joseph D. Tucker   +6 more
doaj   +6 more sources

Willingness to risk death endpoint in HIV cure-related research with otherwise healthy volunteers is misleading [PDF]

Journal of Virus Eradication, 2020
This viewpoint article critiques two recent articles examining ‘willingness to risk death’ to advance HIV cure-related research. The ‘willingness to risk death’ endpoint sends the wrong signal to the HIV cure-related research community about ongoing ...
Karine Dubé, Lynda Dee
doaj   +6 more sources

Ethical and practical considerations for mitigating risks to sexual partners during analytical treatment interruptions in HIV cure-related research [PDF]

HIV Research & Clinical Practice, 2021
Background Background: Analytical treatment interruptions (ATIs) in HIV cure-related research can result in trial participants becoming viremic with HIV, placing HIV-negative sexual partners at elevated risk of acquiring HIV.
Karine Dubé, John Kanazawa, Lynda Dee, Jeff Taylor, Danielle M. Campbell, Brandon Brown, Mallory O. Johnson, Parya Saberi, John A. Sauceda, Jeremy Sugarman, Michael J. Peluso   +10 more
doaj   +8 more sources

Revisiting the ‘sterilising cure’ terminology: a call for more patient-centred perspectives on HIV cure-related research [PDF]

Journal of Virus Eradication, 2019
The literature on HIV therapeutics research is rife with terminology associating ‘sterilisation’ with HIV cure. We find connotations of the word ‘sterilising’ problematic for the HIV cure research field.
Luke Newton, Raúl Necochea, David Palm, Jeff Taylor, Liz Barr, Hursch Patel, Anshula Nathan, Jo Gerrard, Laurie Sylla, Brandon Brown, Karine Dubé   +10 more
doaj   +7 more sources

Community HIV clinicians’ perceptions about HIV cure-related research in the Northwestern United States [PDF]

HIV Research & Clinical Practice, 2022
Background: Research on stakeholder perspectives of HIV cure research has involved people with HIV (PWH), who generally cite the importance of HIV clinician advice in making decisions about trial participation.
Laurie Sylla, Hursch Patel, Michael Louella, Jane Simoni, Karine Dubé   +4 more
doaj   +4 more sources

Increasing the meaningful involvement of women in HIV cure-related research: a qualitative interview study in the United States [PDF]

HIV Research & Clinical Practice, 2023
Background Cisgender women represent over half of people living with HIV globally. However, current research efforts toward a cure for HIV focus predominantly on cisgender men.
Karine Dubé, Elizabeth Barr, Morgan Philbin, Amaya Perez-Brumer, Brian Minalga, Beth Peterson, Dawn Averitt, Bridgette Picou, Krista Martel, Cecilia Chung, María Mejía, Martha Cameron, Gail Graham, Lynda Dee, Dázon Dixon Diallo, Ebony Gordon, Anastasia Korolkova, Typhanye Dyer, Judith D. Auerbach, Eileen Scully, Krista L. Dong, Sara Gianella   +21 more
doaj   +6 more sources

‘With this study, we have hope that something is coming’: community members’ perceptions of HIV cure-related research in Durban, South Africa – a qualitative focus group study [PDF]

HIV Research & Clinical Practice, 2023
Background Developing a cure for HIV remains a global scientific priority. In 2022, the Females Rising through Education, Support and Health (FRESH) cohort launched an HIV cure-related trial involving an analytical treatment interruption (ATI) in Durban,
Karine Dubé, Deli Mthimkhulu, Wiseman Ngcobo, Deborah Mindry, Luyanda Maphalala, Vanessa Pillay, Whitney Tran, Ana Korolkova, Thumbi Ndung’u, Krista Dong   +9 more
doaj   +6 more sources

Ethical and practical considerations for HIV cure-related research at the end-of-life: a qualitative interview and focus group study in the United States [PDF]

BMC Medical Ethics, 2022
Background One of the next frontiers in HIV research is focused on finding a cure. A new priority includes people with HIV (PWH) with non-AIDS terminal illnesses who are willing to donate their bodies at the end-of-life (EOL) to advance the search ...
John Kanazawa, Sara Gianella, Susanna Concha-Garcia, Jeff Taylor, Andy Kaytes, Christopher Christensen, Hursch Patel, Samuel Ndukwe, Stephen A. Rawlings, Steven Hendrickx, Susan Little, Brandon Brown, Davey Smith, Karine Dubé   +13 more
doaj   +7 more sources

"I would really want to know that they had my back": Transgender women's perceptions of HIV cure-related research in the United States. [PDF]

PLoS ONE, 2020
Forty-four percent of Black transgender women are living with HIV, and many face challenges with HIV care engagement. An HIV cure has much to offer this population, however little HIV cure-related research has included them.
Tonia Poteat, Anushka Aqil, Dana Corbett, David Evans, Karine Dubé   +4 more
doaj   +4 more sources