Results 31 to 40 of about 58,279 (299)
Current Opinion in HIV and AIDS, 2013 Interest in finding a potential 'cure' for HIV has taken on greater interest and urgency since the report of an individual who underwent allogeneic stem cell transplant from a CCR5 delta 32 homozygote donor after high-dose chemotherapy for acute myeloid leukemia.
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Plasma HIV viral rebound following protocol-indicated cessation of ART commenced in primary and chronic HIV infection. [PDF]
, 2012 OBJECTIVES: The magnitude of HIV viral rebound following ART cessation has consequences for clinical outcome and onward transmission. We compared plasma viral load (pVL) rebound after stopping ART initiated in primary (PHI) and chronic HIV infection (CHI)
López-Diéguez, María +83 more
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Healthcare Provider Perspectives on HIV Cure Research in Ghana [PDF]
, 2023 Introduction. Antiretroviral therapy (ART) has reduced mortality and improved life expectancy among HIV patients but does not provide a cure. Patients must remain on lifelong medications and deal with drug resistance and side effects.
Benjamin Newcomb +17 more
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Immunotherapeutic approaches to HIV cure and remission [PDF]
, 2021 Purpose of review Despite improvements in the effectiveness of antiretroviral therapy (ART), there are still unmet needs for people living with HIV which drive the search for a cure for HIV infection. The goal of this review is to discuss the challenges
Frater, John, Lee, Ming J, Fidler, S
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Barriers for HIV Cure: The Latent Reservoir [PDF]
AIDS Research and Human Retroviruses, 2018 Thirty-five years after the identification of HIV-1 as the causative agent of AIDS, we are still in search of vaccines and treatments to eradicate this devastating infectious disease. Progress has been made in understanding the molecular pathogenesis of this infection, which has been crucial for the development of the current therapy regimens. However,
Castro-Gonzalez, Sergio +2 more
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Combined approaches for HIV cure
Current Opinion in HIV and AIDS, 2013 A serious effort has begun to develop therapies that may be capable of eradicating established HIV infection in man. Because of the biological complexity of HIV infection that persists despite potent antiretroviral therapy, it is widely believed that if such therapies can be developed they will involve complex, multimodality approaches.
David M, Margolis, Daria J, Hazuda
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Cytokine and chemokine dynamics in acute HIV infection and the impact of early ART initiation [PDF]
, 2021 Introduction: Individuals diagnosed and treated during acute HIV infection (AHI), provide a unique insight into the dynamics of the earliest innate and adaptive immune responses to HIV and the effect of antiretroviral therapy (ART) on these immune ...
Thomas, Grégoire +7 more
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A global survey of HIV-positive people's attitudes towards cure research. [PDF]
, 2017 OBJECTIVES Involvement of people living with HIV (PLHIV) in the design of HIV cure studies is important, given the potential risks to participants. We present results of an international survey of PLHIV to define these issues and inform cure research.
Nelson, M +9 more
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HIV cure research: print and online media reporting in Australia [PDF]
, 2017 OBJECTIVES: While still in its early stages, recent scientific research towards a cure for HIV has generated widespread media interest. The aim of this paper was to explore the ways in which this research has been represented in Australian print and ...
Jayne Lucke (9487628) +10 more
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Journal of the International AIDS Society, 2014 Given the challenge of delivering complex, expensive and potentially harmful antiretroviral therapy (ART) on a global level, there is intense interest in the development of short‐term, well‐tolerated regimens that allow individuals to interrupt therapy indefinitely without experiencing a rebound in viremia. This so‐called “cure” or “remission” might be
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