Results 41 to 50 of about 58,279 (299)

The ethics of talking about ‘HIV cure’ [PDF]

, 2015
Background: In 2008, researchers reported that Timothy Brown (the ‘Berlin Patient’), a man with HIV infection and leukemia, received a stem-cell transplant that removed HIV from his body as far as can be detected.
Keymanthri Moodley, Tucker, Joseph, Siedner, Mark, Moodley, Keymanthri, Mark Siedner, Tucker, Joseph D., Stuart StuartRennie, Rennie, Stuart, Joseph D Tucker, Stuart Rennie, Tucker, Joseph D   +10 more
core   +1 more source

HIV – Is a cure possible?

Indian Journal of Sexually Transmitted Diseases and AIDS, 2019
HIV is a chronic well manageable disease. Highly active antiretroviral therapy improves the quality of life of people living with HIV, but the treatment has to be continued lifelong, as the total cure has not been established. Cost of treatment, drug toxicities, interaction with other drugs and persistence of inflammation and acceleration of the aging ...
openaire   +3 more sources

Ethics of HIV cure research: an unfinished agenda [PDF]

, 2021
BackgroundThe pursuit of a cure for HIV is a high priority for researchers, funding agencies, governments and people living with HIV (PLWH). To date, over 250 biomedical studies worldwide are or have been related to discovering a safe, effective, and ...
Taylor, J., Sugarman, Jeremy, Dubé, K., Sylla, L., Saberi, Parya, Kanazawa, J., Henley, L., Kosmyna, Jan, Jones, Nora, Brown, B., Patel, Hursch, Palm, D., Onaiwu, Morénike Giwa, Sylla, Laurie, Dubé, Karine, Kosmyna, J., Sauceda, John A, Roebuck, C., Kelly, D., Saberi, P., Roebuck, Christopher, Sugarman, J., Johnson, Mallory O, Campbell, D.M., Kanazawa, John, Onaiwu, M.G., Johnson, M.O., Ndukwe, S., Dee, L., Henley, Laney, Patel, H., Sauceda, J.A., Kelly, David, Campbell, Danielle M, Palm, David, Dee, Lynda, Clanton, Orbit, Jones, N., Louella, M., Clanton, O., Taylor, Jeff, Louella, Michael, Brown, Brandon, Ndukwe, Samuel   +43 more
core   +1 more source

Quantitative Eradicative Cure Profile of HIV/AIDS Using Electromagnetic (EM) Wave Destruction Technique [PDF]

, 2017
It is the vibration of an unknown force that causes life and existence. Therefore, for anything to exist it must possess vibration. Vibration produces wave.
Ezekiel Nwose, Umukoro Judith, Umukoro, Judith, Edison Enaibe, Enaibe, Edison A., Erhieyovwe, Erhieyovwe, Erhieyovwe Akpata, Nwose, Ezekiel U.   +7 more
core   +1 more source

Beliefs about HIV cure: A qualitative study of people living with HIV in Soweto, South Africa. [PDF]

South Afr J HIV Med
Background: Rare cases of HIV cure exist. Clinical trials of HIV cure are also underway. However, little is documented about how potential cures are perceived by African people living with HIV, although they are key stakeholders.
Laher F, Mahlangu N, Sibiya M.
europepmc   +3 more sources

Changing concepts of "latent tuberculosis infection" in patients living with HIV infection. [PDF]

, 2011
One third of the world's population is estimated to be infected with Mycobacterium tuberculosis, representing a huge reservoir of potential tuberculosis (TB) disease. Risk of progression to active TB is highest in those with HIV coinfection. However, the
Robert J. Wilkinson, Wood, R, Lawn, Stephen D, Wilkinson, RJ, Robin Wood, Lawn, SD, Wood, Robin, Wilkinson, Robert J, Stephen D. Lawn   +8 more
core   +1 more source

Interests of the Non-Human Primate Models for HIV Cure Research [PDF]

, 2021
Non-human primate (NHP) models are important for vaccine development and also contribute to HIV cure research. Although none of the animal models are perfect, NHPs enable the exploration of important questions about tissue viral reservoirs and the ...
Nicolas Huot, Jacquelin, Beatrice, Caroline Petitdemange, Marie Lazzerini, Huot, Nicolas, Beatrice Jacquelin, Michaela Müller-Trutwin, Terrade, Gauthier, Petitdemange, Caroline, Müller-Trutwin, Michaela, Lazzerini, Marie, Orta Resendiz, Aurelio, Gauthier Terrade, Aurelio Orta Resendiz   +13 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Community HIV Clinicians’ Perceptions about HIV Cure-Related Research in the Northwestern United States [PDF]

, 2022
BACKGROUND: Research on stakeholder perspectives of HIV cure research has involved people with HIV (PWH), who generally cite the importance of HIV clinician advice in making decisions about trial participation.
Michael Louella, Hursch Patel, Simoni, Jane, Jane Simoni, Karine Dubé, Patel, Hursch, Louella, Michael, Laurie Sylla, Sylla, Laurie, Dubé, Karine   +9 more
core   +1 more source