Results 91 to 100 of about 5,218,351 (211)

Generation and Characterization of a Bivalent HIV-1 Subtype C gp120 Protein Boost for Proof-of-Concept HIV Vaccine Efficacy Trials in Southern Africa.

PLoS ONE, 2016
The viral envelope glycoprotein (Env) is the major target for antibody (Ab)-mediated vaccine development against the Human Immunodeficiency Virus type 1 (HIV-1).
Carlo Zambonelli, Antu K Dey, Susan Hilt, Samuel Stephenson, Eden P Go, Daniel F Clark, Mark Wininger, Celia Labranche, David Montefiori, Hua-Xin Liao, Ronald I Swanstrom, Heather Desaire, Barton F Haynes, Andrea Carfi, Susan W Barnett   +14 more
doaj   +1 more source

Discontinuous sequence change of human immunodeficiency virus (HIV) type 1 env sequences in plasma viral and lymphocyte-associated proviral populations in vivo:implications for models of HIV pathogenesis [PDF]

, 1991
Sequence change in different hypervariable regions of the external membrane glycoprotein (gp120) of human immunodeficiency virus type 1 (HIV-1) was studied.
Zhang, L Q, Brown, A J, Balfe, P, McOmish, F, Ludlam, C A, Simmonds, P   +5 more
core  

Mapping Reactivities of Murine Monoclonal Antibodies to the External Envelope Glycoprotein (gp120) of Human Immunodeficiency Virus Type 1 (HIV-1)

, 1990
A group of monoclonal antibodies generated from the envelope glycoprotein (gp120) of human immunodeficiency virus type 1B (HIV-1B) or type 1RF (HIV-1RF) were selected for characterization and epitope mapping studies.
Johnson, Donald Gibson
core   +1 more source

Surfactant Protein D modulates HIV infection of both T-cells and dendritic cells.

PLoS ONE, 2013
Surfactant Protein D (SP-D) is an oligomerized C-type lectin molecule with immunomodulatory properties and involvement in lung surfactant homeostasis in the respiratory tract.
Jens Madsen, Gaurav D Gaiha, Nades Palaniyar, Tao Dong, Daniel A Mitchell, Howard W Clark   +5 more
doaj   +1 more source

Quercetin ameliorates HIV-1 gp120 protein-induced intestinal barrier dysfunction by inhibiting the activation of the ERK1/2 signaling pathway in a Caco-2 cell model

AIDS Research and Therapy
Background People living with HIV (PLWH) frequently experience non-AIDS comorbidities, driven in part by persistent intestinal barrier dysfunction and systemic inflammation.
Lijiao Zhu, Jiangyu Yan, Qinghui Wang, Xiaoqing He, Xiaolei Xu, Jiadan Yang, Jing Ouyang   +6 more
doaj   +1 more source

HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells.

PLoS Pathogens, 2007
The human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp120 is a vaccine immunogen that can signal via several cell surface receptors.
Meimei Shan, Per Johan Klasse, Kaustuv Banerjee, Antu K Dey, Sai Prasad N Iyer, Robert Dionisio, Dustin Charles, Lila Campbell-Gardener, William C Olson, Rogier W Sanders, John P Moore   +10 more
doaj   +1 more source

Highly efficient production of HIV-1AD8 gp120 in mammalian cells

Journal of Virology
Human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins (Envs) interact with the CD4 receptor and CCR5/CXCR4 coreceptor expressed on target cells to mediate viral entry. Infection is initiated when the HIV-1 gp120 subunit of Envs binds to host
Tanvi Mathur, Shamim Ahmed, Durgadevi Parthasarathy, Alon Herschhorn   +3 more
doaj   +1 more source

Atomic force microscopy fishing and mass spectrometry identification of gp120 on immobilized aptamers

International Journal of Nanomedicine, 2014
Yuri D Ivanov,1 Natalia S Bukharina,1 Tatyana O Pleshakova,1 Pavel A Frantsuzov,1 Elena Yu Andreeva,1 Anna L Kaysheva,1,2 Victor G Zgoda,1 Alexander A Izotov,1 Tatyana I Pavlova,1 Vadim S Ziborov,1 Sergey P Radko,1 Sergei A Moshkovskii,1 Alexander I ...
Ivanov YD, Bukharina NS, Pleshakova TO, Frantsuzov PA, Andreeva EY, Kaysheva AL, Zgoda VG, Izotov AA, Pavlova TI, Ziborov VS, Radko SP, Moshkovskii SA, Archakov AI   +12 more
doaj  

HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV

Journal of Translational Medicine, 2010
It is well established that HIV-1 infection typically involves an interaction between the viral envelope protein gp120/41 and the CD4 molecule followed by a second interaction with a chemokine receptor, usually CCR5 or CXCR4.
Cicala Claudia, Arthos James, Fauci Anthony   +2 more
doaj  

Preliminary evaluation of KYNA ameliorates neuronal pyroptosis induced by HIV-1 gp120

International Journal of Infectious Diseases
Backgrounds: HIV-associated neurocognitive disorders (HAND) are the common complications in the central nervous system (CNS), mainly causing HIV dementia and leading to serious social economic load.
Dr Xuefeng Gao, Mr Wenchang Wang, Ms Yanjun Zhang, Ms Miaochun Chen, Prof Min Long, Mr. Xuefeng Gao   +5 more
doaj   +1 more source