Results 161 to 170 of about 5,218,351 (211)

Differential selectivity of microglia and astrocytes in HIV-1 gp120-induced synaptic pruning. [PDF]

Brain
Watson ZT, Valdebenito-Silva S, Spurgat M, Ru W, Zheng J, Maurelli MK, Liang Y, Yuan S, Eugenin E, Tang SJ.   +9 more
europepmc   +1 more source

Molecular factors associated with lung cancer in people living with HIV. [PDF]

Braz J Infect Dis
Bautista-Rojas ID, Figueroa-Navarrete J, Reyes-Hernandez DL, Rivera-Toledo E.   +3 more
europepmc   +1 more source

Signal Peptide of HIV Envelope Protein Impacts Glycosylation and Antigenicity of gp120 [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Significant heterogeneity exists in the structure and antigenicity of HIV-1 envelope protein (Env) gp120 due, in part, to various posttranslational modifications. Using glycan and antigenic analysis, we show that the signal peptide (SP) of HIV Env can impact the glycan profile of gp120, which in turn impacts antigenicity ...
Claudia Cicala, Jason Yolitz, James Arthos   +2 more
exaly   +4 more sources

HIV-1 Envelope Protein gp120 Promotes Proliferation and the Activation of Glycolysis in Glioma Cell [PDF]

Cancers, 2018
Patients infected with human immunodeficiency virus (HIV) are more prone to developing cancers, including glioblastomas (GBMs). The median survival for HIV positive GBM patients is significantly shorter than for those who are uninfected, despite the fact that they receive the same treatments.
Lilia Kucheryavykh, Aníbal Valentín-Acevedo, Yuriy V Kucheryavykh   +2 more
exaly   +4 more sources

Specific Binding of HIV-1 Envelope Protein gp120 to the Structural Membrane Proteins Ezrin and Moesin

Virus Research, 1997
The observation that HIV in vitro can infect CD4- and Gal-C-negative brain cell lines has stimulated this study to identify alternative gp120-binding proteins on brain cells. HIV-1 gp120 binding proteins of the CD4-negative and Gal-C-negative, non-productively infectable human glioblastoma cell line D54 were purified by affinity chromatography over a ...
Volker Ter Meulen, C Weise, V Ter Meulen
exaly   +3 more sources

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Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons

NeuroReport, 1996
A new in vitro system comprising a pure population of neurons, human NT cells, was used to characterize the direct neurotoxic effect of HIV-1 envelope protein gp120. Cytotoxicity was monitored by a quantitative assay after exposure to recombinant gp120 in the presence or absence of other reagents.
P, Wu, P, Price, B, Du, W C, Hatch, E F, Terwilliger   +4 more
openaire   +2 more sources

HIV-1 envelope protein gp120 affects phenotype and function of monocytes in vitro

Journal of Leukocyte Biology, 1994
Abstract We investigated the effect of human immunodeficiency virus type 1 (HIV-1) recombinant gp120 (rec.gp120) on phenotype and function of cultured monocytes. Rec.gp120 significantly reduced the accessory function of monocytes to stimulate autologous lymphocytes with anti-CD3, the Fc receptor–mediated chemiluminescence of monocytes ...
I, Dürrbaum-Landmann, E, Kaltenhäuser, H D, Flad, M, Ernst   +3 more
openaire   +2 more sources

The HIV-1 envelope protein GP120 induces neuronal apoptosis in hippocampal slices

NeuroReport, 1996
The HIV-1 envelope protein gp120 produces neuronal cell damage in primary cultures of a variety of cell types including hippocampal and retinal ganglion cell neurons. The properties of primary cell cultures are, however, often markedly different from those of cells living in their normal environment.
D, Aggoun-Zouaoui, C, Charriaut-Marlangue, S, Rivera, I, Jorquera, Y, Ben-Ari, A, Represa   +5 more
openaire   +2 more sources