Results 221 to 230 of about 32,363 (272)
Subgroup Identification via Multiple Change Point Detection: Methods and Applications
WIREs Computational Statistics, Volume 18, Issue 2, June 2026.Subgroup identification methods facilitate the discovery of clinically meaningful subpopulations with differing disease progression, improving personalized risk assessment and treatment strategies. ABSTRACT Subgroup identification is a significant research area in statistics and machine learning, aiming to partition a heterogeneous population into more
Yaguang Li +3 more
wiley +1 more source
The sounds of silencing: dynamic epigenetic control of HIV latency. [PDF]
Curr Opin HIV AIDSNguyen K, Karn J.
europepmc +1 more source
American Journal of Reproductive Immunology, Volume 95, Issue 6, June 2026.ABSTRACT HIV transmission through the female and male reproductive tracts is governed by spatially organized interactions between virions, epithelial barriers, and tissue‐resident immune cells. Imaging approaches have been central to defining these earliest events, progressing from classical histology and immunohistochemistry (IHC) to modern ...
Ann M. Carias +3 more
wiley +1 more source
Editorial: HIV Latency: novel insights into the viral reservoir and therapeutic strategies. [PDF]
Front Cell Infect Microbiolde Oliveira ACS, Abreu CM.
europepmc +1 more source
The HIV Reservoir in the Female Reproductive Tract
American Journal of Reproductive Immunology, Volume 95, Issue 6, June 2026.ABSTRACT Antiretrovirals can prevent the spread of replicating HIV within the host and decrease the virus in plasma to levels undetectable in clinical assays, and in genital secretions to untransmissible levels. However, during effective treatment with antiretrovirals, infectious HIV persists lifelong because the virus integrates into the host's DNA ...
Sean M. Hughes, Lisa M. Frenkel
wiley +1 more source
A First-in-Class Dual Degrader of Bcl-2/Bcl-xL Reverses HIV Latency and Minimizes Ex Vivo Reservoirs from Patients. [PDF]
Int J Mol SciChang LC +5 more
europepmc +1 more source
Mental health service users' pre‐ and post‐therapy hospitalization rates: A data linkage study
British Journal of Clinical Psychology, Volume 65, Issue 2, Page 625-638, June 2026.Abstract Objective To examine the long‐term impact of psychological therapy on physical and mental health hospitalizations. Methods The study design combined case control and data linkage methodologies. Data from 3742 psychological therapies service (PTS) service users and 72,500 matched controls were merged with hospitalizations data in Northern ...
Julie‐Ann Jordan +3 more
wiley +1 more source
SARS-CoV-2 Modulation of HIV Latency Reversal in a Myeloid Cell Line: Direct and Bystander Effects. [PDF]
VirusesJarmoluk P +7 more
europepmc +1 more source
Clinical Transplantation, Volume 40, Issue 6, June 2026.ABSTRACT Background Pneumocystis jirovecii is an opportunistic fungus responsible for Pneumocystis pneumonia (PJP) in hosts with impaired cell‐mediated immunity, particularly solid organ transplant recipients. The aim of our study was to identify risk factors associated with PJP in kidney transplant recipients (KTRs).
Solenne Hulot +9 more
wiley +1 more source
The impact of accumulating immune adaptation in circulating strains of HIV‐1
HIV Medicine, Volume 27, Issue 6, Page 918-934, June 2026.Abstract Background Mutations in human immunodeficiency virus type 1 (HIV‐1) enable the virus to evade recognition and killing by human leucocyte antigen (HLA)‐restricted T cells. These viral adaptations are specific to the HLA type of individuals and are therefore evident as HLA allele‐HIV sequence associations at the population level. Most studies of
Marwah Al‐kaabi +7 more
wiley +1 more source