Results 71 to 80 of about 799,404 (198)
Mathematical Models of HIV Latency [PDF]
, 2017 Viral latency is a major barrier to curing HIV infection with antiretroviral therapy, and consequently, for eliminating the disease globally. The establishment, maintenance, and potential clearance of latent infection are complex dynamic processes and can be best understood and described with the help of mathematical models.
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Commercial sex and the spread of HIV in four cities in sub-Saharan Africa. [PDF]
, 2001 OBJECTIVE: To examine whether commercial sex transactions were more common and/or transmission between sex workers and clients more efficient in two African cities with high HIV prevalence (Kisumu, Kenya and Ndola, Zambia) compared with two with ...
Morison, L. +18 more
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HIV Latency in the Humanized BLT Mouse [PDF]
Journal of Virology, 2012 ABSTRACT Even after extended treatment with powerful antiretroviral drugs, HIV is not completely eliminated from infected individuals. Latently infected CD4 + T cells constitute one reservoir of replication-competent HIV that needs to be eliminated to completely purge virus ...
Matthew D, Marsden +8 more
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Validation of replicative phenotyping to detect and assign HIV-1 resistance in clinical specimens [PDF]
, 2009 The ability of HIV-1 to develop resistance to antiretroviral drugs has limited the overall efficacy of combination therapy to suppress viral replication.
Louvel, Séverine
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An Integrated Overview of HIV-1 Latency [PDF]
Cell, 2013 Despite significant advances in our understanding of HIV, a cure has not been realized for the more than 34 million infected with this virus. HIV is incurable because infected individuals harbor cells where the HIV provirus is integrated into the host's DNA but is not actively replicating and thus is not inhibited by antiviral drugs.
Ruelas, Debbie S, Greene, Warner C
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Adaptive Latency Insensitive Protocols [PDF]
, 2007 Latency-insensitive design copes with excessive delays typical of global wires in current and future IC technologies. It achieves its goal via encapsulation of synchronous logic blocks in wrappers that communicate through a latency-insensitive protocol ...
Casu, Mario Roberto, Macchiarulo, Luca
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The epidemiology of HSV-2 infection and its association with HIV infection in four urban African populations. [PDF]
, 2001 OBJECTIVES: To estimate age- and sex-specific herpes simplex virus type-2 (HSV-2) prevalence in urban African adult populations and to identify factors associated with infection. DESIGN AND METHODS: Cross-sectional, population-based samples of about 2000
Robinson, NJ +24 more
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[Molecular basis of HIV-1 latency - part I: physiology of HIV-1 latency].
Medecine sciences : M/S, 2010 L’introduction de la multithérapie active en 1996 s’est avérée très efficace et avait entretenu l’espoir d’éradiquer le virus du Sida. Malheureusement, des obstacles à son éradication sont rapidement apparus, notamment la mise en évidence du phénomène de latence virale dans les principales cellules cibles du virus, dont les lymphocytes T CD4+ et les ...
Schwartz, Christian +6 more
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Latency: the hidden HIV-1 challenge [PDF]
Retrovirology, 2006 AbstractEradication of HIV-1 from an infected individual cannot be achieved by current regimens. Viral reservoirs established early during the infection remain unaffected by anti-retroviral therapy for a long time and are able to replenish systemic infection upon interruption of the treatment.
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Media communication in HIV/AIDS and STI : young people perspectives
, 2011 Background: Although recent developments of antiretroviral drugs for treating HIV/AIDS appear promising, prevention of infection is the only safeguard; and the key factor to preventing infection, be it of HIV or any other sexually transmitted disease, is
Razaghi, Kazem (R20892)
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