Results 81 to 90 of about 799,404 (198)
Identification of Novel HIV-1 Latency-Reversing Agents from a Library of Marine Natural Products
Natural products originating from marine and plant materials are a rich source of chemical diversity and unique antimicrobials. Using an established in vitro model of HIV-1 latency, we screened 257 pure compounds from a marine natural product library and
Andersen, Raymond J. +18 more
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HIV Types, Groups, Subtypes and Recombinant Forms: Errors in Replication, Selection Pressure and Quasispecies [PDF]
HIV-1 is a chimpanzee virus which was transmitted to humans by several zoonotic events resulting in infection with HIV-1 groups M P, and in parallel transmission events from sooty mangabey monkey viruses leading to infections with HIV-2 groups A H.
Eberle, Josef, Gürtler, Lutz
core +1 more source
Histone deacetylase inhibitors and HIV latency [PDF]
Interest has re-emerged in approaches to eradicate HIV infection. A series of modifications of nucleosomal histones within chromatin are a key mechanism of HIV gene regulation that alters the recruitment of transcription factors to viral DNA. The balance of these histone modifications in the vicinity of the HIV LTR plays an important role in the ...
openaire +2 more sources
The effects of age on associations between markers of HIV progression and markers of metabolic function including albumin, haemoglobin and lipid concentrations. [PDF]
We investigated whether age modified associations between markers of HIV progression, CD4 T lymphocyte count and HIV RNA viral load (VL), and the following markers of metabolic function: albumin, haemoglobin, high-density lipoprotein cholesterol (HDL-C),
C Leen +63 more
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HIV terminology and appropriate language use guidelines. [PDF]
We have seen significant advancements in HIV treatment and prevention in recent years. However, the language used when talking or writing about HIV is often out-dated and stigmatising.
core
"Sources of information for this report: Kansas HIV/AIDS Surveillance System (eHARS)"HIV/AIDS in Kansas, Annual Report, December 2009 HIV/AIDS in Kansas, Annual Report, December 2010 HIV/AIDS in Kansas, Annual Report, December 2011 HIV/AIDS in ...
Kansas. HIV/AIDS Surveillance Program
core
Contains Incident, Prevalent, and Cumulative AIDS Cases in Kansas as of ... by Date of Report "HIV/AIDS and STD Semiannual Report is a publication of the Kansas Department of Health and Environment with funding assistance from the Centers for Disease ...
HIV/AIDS Surveillance Program
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Waking Up the Sleepers: HIV Latency and Reactivation
In a patient infected with HIV-1, the presence of latently infected cells from which the virus can be reactivated and rekindle HIV infection in the patient necessitates lifelong administration of antiretroviral treatment.
Hoi Ping Mok, Andrew Lever
doaj +1 more source
Reactivation capacity by latency-reversing agents ex vivo correlates with the size of the HIV-1 reservoir [PDF]
Objective: HIV-1 reservoirs are the major hurdle to virus clearance in combination antiretroviral therapy (cART)-Treated patients. An approach to eradicating HIV-1 involves reversing latency in cART-Treated patients to make latent cells visible to the ...
De Wit, S +28 more
core +1 more source
Background: The latent HIV-1 reservoir in treated patients primarily consists of resting memory CD4+ T cells. Stimulating the T-cell receptor (TCR), which facilitates transition of resting into effector T cells, is the most effective strategy to purge ...
Thijs van Montfort +17 more
doaj +1 more source

