Results 151 to 160 of about 58,529 (279)

HIV protease inhibitors, the lipodystrophy syndrome and polycystic ovary syndrome--is there a link? [PDF]

, 1999
J D Wilson, Richard J.C. Dunham, Adam Balen   +2 more
openalex   +1 more source

Should We Advance Our Understanding of Immunoglobulin E in Viral Immunity?

Immunology, EarlyView.
Immunoglobulin E has been extensively studied in allergies and parasitic diseases. Antigen‐specific IgE has been identified as part of the humoral response to viruses. This revision speculates on possible functionalities for IgE, such as neutralisation, cytotoxicity and immunopathology of viral diseases, and provide insights about gaps to fill in ...
Amanda Izeli Portilho, Valéria Oliveira Silva, Luis Fernando de Macedo Brigido, Elizabeth De Gaspari   +3 more
wiley   +1 more source

Single atom changes in newly synthesized HIV protease inhibitors reveal structural basis for extreme affinity, high genetic barrier, and adaptation to the HIV protease plasticity. [PDF]

Sci Rep, 2020
Bulut H, Hattori SI, Aoki-Ogata H, Hayashi H, Das D, Aoki M, Davis DA, Rao KV, Nyalapatla PR, Ghosh AK, Mitsuya H.   +10 more
europepmc   +1 more source

Alterations in the Immune Response of Human Immunodeficiency Virus (HIV)-Infected Subjects Treated with an HIV-Specific Protease Inhibitor, Ritonavir

, 1996
Anthony D. Kelleher, Andrew Carr, John Zaunders, David A. Cooper   +3 more
openalex   +1 more source

Association of the IL‐6R rs2228145 polymorphism with diabetic nephropathy: A case‐control study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Introduction The pathogenesis of diabetes mellitus (DM) and its complications has been previously linked to elevated levels of interleukin‐6 (IL‐6); IL‐6 triggers intracellular pathways through interaction with the IL‐6 receptor (IL‐6R). This study aimed to determine the association of single nucleotide polymorphisms (SNPs) IL‐6 −597G/A ...
Pavla Izakovicova, Simona Slezakova, Tereza Deissova, Hana Poskerova, Petra Borilova Linhartova, Ladislav Dusek, Katerina Kankova, Lydie Izakovicova Holla   +7 more
wiley   +1 more source

Semicochliodinol A and B: Inhibitors of HIV-1 Protease and EGF-R Protein Tyrosine Kinase Related to Asterriquinones Produced by the Fungus Chrysosporium merdarium.

, 1997
Andreas Fredenhagen, Frank Petersen, Marina Tintelnot‐Blomley, Johannes Rösel, Helmut Mett, Paul Hug   +5 more
openalex   +2 more sources

Virologic and CD4 Response to Treatment with Nelfinavir in Therapy Experienced, Protease Inhibitor Naive HIV-Infected Children: 48 Week Follow-Up [PDF]

, 1999
Lisa A Martel, Megan Valentine, Lori Ferguson, Penelope Muelenaer, Randall G. Fisher, Samuel L. Katz, Ross E. McKinney   +6 more
openalex   +1 more source

Developing downstream processes for the purification of recombinant proteins and small molecules from Nicotiana benthamiana biomass

Plant Biotechnology Journal, EarlyView.
Summary Nicotiana benthamiana (Australian tobacco) has become a major host for plant‐based recombinant protein production, especially using transient expression. Once a candidate protein has been designed and produced in a suitable variety (e.g. facilitated humanized glycosylation) under reproducible conditions (e.g.
J. F. Buyel
wiley   +1 more source

Virological treatment failure of protease inhibitor therapy in an unselected cohort of HIV-infected patients

, 1997
Gerd Fätkenheuer, Albert Theisen, Jürgen K. Rockstroh, Tanja Grabow, Christian Wicke, Katja Becker, Ulrike Wieland, Herbert Pfister, Marcel Reiser, P Hegener, Caspar Franzen, Achim Schwenk, Bernd Salzberger   +12 more
openalex   +1 more source

Dried Blood Spot Analysis for Simultaneous Quantification of Antiepileptic Drugs Using Liquid Chromatography–Tandem Mass Spectrometry

Rapid Communications in Mass Spectrometry, Volume 39, Issue 16, 30 August 2025.
ABSTRACT Rationale Dried blood spot (DBS) sampling for the therapeutic drug monitoring of antiepileptic drugs offers practical advantages, including minimal invasiveness and ease of collection. However, for precise therapeutic management, its accuracy and reliability in quantification need to be validated.
Mariam M. Abady, Ji‐Seon Jeong, Ha‐Jeong Kwon   +2 more
wiley   +1 more source