Results 191 to 200 of about 58,529 (279)

Combination Antiretroviral Therapy Including a Protease Inhibitor Eliminated the Transfusion Requirements of HIV-Infected Individuals With Anemia of Chronic Disease

, 1998
Eleftherios Mylonakis, Brian P. Dickinson, Alexander Feller, Joseph D. Sweeney, Fred J. Schiffman, Jody Rich, Timothy Flanigan   +6 more
openalex   +1 more source

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, Volume 64, Issue 27, July 1, 2025.
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source

Human Cervix Chip: A Preclinical Model for Studying the Role of the Cervical Mucosa and Microbiome in Female Reproductive Health

BioEssays, Volume 47, Issue 7, July 2025.
The microfluidic Cervix Chip is an in vitro model of the human cervix lined by cervical epithelium interfaced with stromal cells cultured under dynamic flow that represents a new preclinical platform for studying mucosal immunity, host‐microbiome interactions, infections, fertility, and pregnancy health.
Zohreh Izadifar, Anna Stejskalova, Aakanksha Gulati, Ola Gutzeit, Donald E. Ingber   +4 more
wiley   +1 more source

Protease inhibitors in HIV-infected injecting drug users in Amsterdam

, 1998
Janke Schinkel, R A Coutinho, E J van Ameijden   +2 more
openalex   +1 more source

Chemical Components of the Dried Latex of Euphorbia resinifera Berg and Its Medicinal Features

Chemistry &Biodiversity, Volume 22, Issue 7, July 2025.
ABSTRACT A great deal of research has been carried out on the latex of Euphorbia resinifera Berg, which is an important source of several compounds of therapeutic and medicinal interest. Extraction, synthesis, and hemi synthesis pathways continue to reveal the existence of other new products with anticancer, antioxidant, antidiuretic, and antimalarial ...
Doaa Hammad, El‐Mahdi Ourhzif, Salha Hamri, Hafid Abderrafia, Mostafa Khouili, Maria Dolors Pujol   +5 more
wiley   +1 more source

Salvage therapy in HIV-positive patients with a previous therapeutic experience with protease inhibitors

, 1999
Franco Maggiolo, Renato Maserati, Angelo Pan, Francesco Castelli, Fredy Suter   +4 more
openalex   +1 more source

IGF2BP2 binding to CPSF6 facilitates m6A‐mediated alternative polyadenylation of PUM2 and promotes malignant progression in ovarian cancer

Clinical and Translational Medicine, Volume 15, Issue 7, July 2025.
The interaction between m6A and APA is mediated by the m6A regulator IGF2BP2 and the APA factor CPSF6 The transcripts harbouring m6A modification tend to use the proximal polyadenylation signal (PAS) in ovarian cancer (OC) PUM2 promotes the malignant progression of OC through its m6A methylation and APA processing .
Xin Luo, Qinglv Wei, Lingcui Xie, Ningxuan Chen, Bin Gu, Jiani Xu, Xiaoyan Jiang, Xinzhao Zuo, Hongyan Zhao, Xiaoyi Liu, Yu Yang, Tao Liu, Yong Zhu, Ping Yi, Jing Xu   +14 more
wiley   +1 more source

Decoding MHC loss: Molecular mechanisms and implications for immune resistance in cancer

Clinical and Translational Medicine, Volume 15, Issue 7, July 2025.
Tumour cells evade immune surveillance by downregulating MHC expression through transcriptional repression, lysosomal degradation and post‐translational modifications. Pharmacological agents interventing epigenetic and metabolic can upregulate MHC expression and improve T cell activation.
Pei Lin, Yunfan Lin, Xu Chen, Xinyuan Zhao, Li Cui   +4 more
wiley   +1 more source

HIV protease inhibitors saquinavir and nelfinavir are potent inhibitors of cathepsin L activity: A potential treatment for COVID-19 patients

, 2020
Montenegro MF, Al-Abed Y, He M, Tracey KJ, Billiar TR.   +4 more
europepmc   +1 more source

HAART and lungs: do HIV protease inhibitors impact cancer risk? [PDF]

AIDS, 2015
Uldrick TS.
europepmc   +1 more source