Results 101 to 110 of about 36,601 (210)

Polyphenols as Natural Therapeutics for Dental Infections and Oral Inflammation: Mechanisms and Clinical Perspectives

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Polyphenol‐rich plant extracts provide natural immunomodulatory protection for oral health through complementary antioxidant, antibacterial, and anti‐inflammatory actions. Their potential to reduce harmful microbial activity and inflammation highlights the promise of dietary polyphenols as a natural strategy for maintaining oral health and preventing ...
Deepa Subramanian, Divya Krishnamoorthi, Gowtham Kannan, Benedict Mathews Paul   +3 more
wiley   +1 more source

Effects of Cd8a Gene Knockout on Gut Microbiota and Liver Metabolism

Immunity, Inflammation and Disease, Volume 14, Issue 10, October 2026.
ABSTRACT Objective Evaluate the effects of CD8+ T cell defects caused by Cd8a gene knockout on gut microbiota and hepatic metabolism, and preliminarily explore the underlying mechanisms. Methods The Cd8a gene was knocked out in mice to generate Cd8a knockout mice.
Zhongshi Dai, Chuan Wang, Hu Mu, Chunxiu Hou, Jing Tang, Jinhai Ma, Mingxing Zhu, Bingshuo Qian   +7 more
wiley   +1 more source

Association Between HIV Infection Duration and Left Ventricular Concentric Remodeling and Myocardial Fibrosis: A Cross‐Sectional Study Using Cardiac MRI

Journal of Magnetic Resonance Imaging, Volume 64, Issue 4, Page 1037-1049, October 2026.
ABSTRACT Background Antiretroviral therapy has transformed HIV into a chronic condition, yet cardiac injury remains a major issue. Purpose To assess the ability of cardiac MR imaging markers to predict cardiac injury and disease progression in HIV‐infected individuals. Study Type Prospective.
Chunyan Deng, Wei Sun, Tianhu Gao, Haixia Chen, Lu Liu, Ran Li   +5 more
wiley   +1 more source

Nasopharyngeal Carriage Rate, Risk Factors, and Co‐Resistance Patterns of Methicillin‐Resistant Staphylococcus aureus in Ethiopia: Systematic Review and Meta‐Analysis

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
This systematic review and meta‐analysis show that nasopharyngeal carriage of methicillin‐resistant Staphylococcus aureus remains an important public health concern in Ethiopia. High resistance to commonly used antibiotics and significant associations with prior hospitalization and antibiotic use highlight the need for strengthened antimicrobial ...
Simachew Getaneh Endalamew, Sofiya Ayalew Kebede, Solomon Keflie Assefa, Adem Tsegaw Zegeye, Belayneh Jejaw Abate, Dejen kahsay Asgedom, Eliyas Addisu Taye, Endalew Minwuye Andargie, Eyob Akalewold Alemu, Halima Ayalew Kebede, Alebachew Tilahun Wassie, Andnet Yirga Assefa, Yihenew Getahun Ambaw, Helen Brhan Alemaw   +13 more
wiley   +1 more source

Reservoir differences across HIV-1 subtypes: a systematic review to guide cure research

Frontiers in Immunology
IntroductionDespite effective antiretroviral therapy, HIV-1 persists as a viral reservoir and remains a major barrier to a durable cure. Reservoir size and dynamics are central determinants of the success of cure strategies.
Myrthe S. Willemsen, Myrthe S. Willemsen, Anniek A. N. Tanja, Sody Munsaka, Damalie Nakanjako, Damalie Nakanjako, Thumbi Ndung’u, Thumbi Ndung’u, Thumbi Ndung’u, Thumbi Ndung’u, Maria A. Papathanasopoulos, Kevin Jenniskens, Kevin Jenniskens, Giulia Sinatti, Giulia Sinatti, Jori Symons, Annemarie M. J. Wensing, Monique Nijhuis, Monique Nijhuis, Ganna Rozhnova, Ganna Rozhnova, Ganna Rozhnova, Ganna Rozhnova   +22 more
doaj   +1 more source

Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management

MedComm, Volume 7, Issue 10, October 2026.
A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley   +1 more source

Intact proviruses are enriched in the colon and associated with PD-1+TIGIT− mucosal CD4+ T cells of people with HIV-1 on antiretroviral therapyResearch in context

EBioMedicine
Summary: Background: The persistence of intact replication-competent HIV-1 proviruses is responsible for the virological rebound off treatment. The gut could be a major reservoir of HIV-1 due to the high number of infected target cells.
Camille Vellas, Manon Nayrac, Nived Collercandy, Mary Requena, Nicolas Jeanne, Justine Latour, Chloé Dimeglio, Michelle Cazabat, Karl Barange, Laurent Alric, Nicolas Carrere, Guillaume Martin-Blondel, Jacques Izopet, Pierre Delobel   +13 more
doaj   +1 more source

Harnessing Natural Killer Cells: From Neuroimmunology to Novel Therapies for Central Nervous System Diseases

MedComm, Volume 7, Issue 10, October 2026.
This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley   +1 more source

Delivering CRISPR to the HIV-1 reservoirs

Frontiers in Microbiology
Human immunodeficiency virus type 1 (HIV-1) infection is well known as one of the most complex and difficult viral infections to cure. The difficulty in developing curative strategies arises in large part from the development of latent viral reservoirs (LVRs) within anatomical and cellular compartments of a host.
Theodore E. Gurrola, Theodore E. Gurrola, Samuel N. Effah, Samuel N. Effah, Ilker K. Sariyer, Will Dampier, Will Dampier, Michael R. Nonnemacher, Michael R. Nonnemacher, Michael R. Nonnemacher, Brian Wigdahl, Brian Wigdahl, Brian Wigdahl   +12 more
openaire   +3 more sources

Latency Reversing Agents and the Road to an HIV Cure

Pathogens
HIV-1 infection cannot be cured due to the presence of HIV-1 latently infected cells. These cells do not produce the virus, but they can resume virus production at any time in the absence of antiretroviral therapy. Therefore, people living with HIV (PLWH)
Louis Tioka, Rafael Ceña Diez, Anders Sönnerborg, Maarten A. A. van de Klundert   +3 more
doaj   +1 more source