Results 111 to 120 of about 34,599 (210)
Artificial lipidation of proteins and peptides: from mechanism to clinical applications
The FEBS Journal, Volume 293, Issue 5, Page 1269-1284, March 2026.Artificial lipidation transforms protein and peptide therapeutics by attaching fatty acid chains through reversible or permanent chemical strategies. This biomimetic approach delivers four key therapeutic advantages: extended circulation times (enabling weekly instead of daily dosing), alternative administration routes including oral delivery, precise ...
Jiaming Mu, Emily Vong, Sheiliza Carmali
wiley +1 more source
The role of Tat in HIV latency and reactivation
Frontiers in ImmunologyHIV persists during therapy due the existence of a latently infected reservoir in which viral gene expression is silenced. This reservoir thus represents the primary barrier to a cure for HIV.
David M. Margolis, Edward P. Browne
doaj +1 more source
HIV Medicine, Volume 27, Issue 3, Page 442-458, March 2026.Abstract Objectives Initial HIV cure interventions may not meet expert‐defined target product profiles (TPPs; desired treatment attributes). Understanding how people with HIV perceive ideal and likely HIV cure attributes is essential. This study examined which optimal TPP attributes people with HIV consider important and which minimum attributes and ...
Maaike A. J. Noorman +6 more
wiley +1 more source
International Journal of Dermatology, Volume 65, Issue 3, Page 444-455, March 2026.ABSTRACT Gonorrhea, a common sexually transmitted infection caused by Neisseria gonorrhoeae, represents an escalating global public health threat due to antimicrobial resistance. The current review explores diverse approaches around the globe to gonorrhea management across various settings, with a focus on diagnostic strategies, treatment practices ...
Andrei Tanasov +2 more
wiley +1 more source
Sex‐Specific Factors Influencing HIV Infection
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Immune responses are key in controlling viral infections such as HIV‐1, which remains a global challenge to public health. X/Y‐chromosome‐encoded genes and sex steroid hormones can modulate immune cells and drive distinct patterns of gene and protein expression involved in antiviral function, impacting sex‐dependent immune responses and ...
Maria Pujantell, Marcus Altfeld
wiley +1 more source
How Does Biological Sex Impact Mucosal Bacterial Infection? Mucosal Defenses and Bacterial Detection
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Urinary tract infections possess substantial sex disparities in the incidence, immune response, and progression of infection. Some of these distinctions may be due to sexual dimorphism in mucosal barriers or sex differences in the initial immune response to infection.
Laura Ramirez Finn, Molly A. Ingersoll
wiley +1 more source
The latent HIV reservoir: current advances in genetic sequencing approaches. [PDF]
mBio, 2023 Moar P +3 more
europepmc +1 more source
Respirology, Volume 31, Issue 3, Page 232-235, March 2026.
Takashi Hirama +2 more
wiley +1 more source
Targeting the HIV reservoir: chimeric antigen receptor therapy for HIV cure. [PDF]
Chin Med J (Engl), 2023 Li S +5 more
europepmc +1 more source
Impact of misclassified defective proviruses on HIV reservoir measurements. [PDF]
Nat Commun, 2023 Reeves DB +7 more
europepmc +1 more source