Results 161 to 170 of about 34,599 (210)
Increase in HIV reservoir and T cell immune response after CoronaVac vaccination in people living with HIV. [PDF]
HeliyonPeng X, Zhu X, Liu X, Huang Y, Zhu B.
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The replication-competent HIV reservoir is a genetically restricted, younger subset of the overall pool of HIV proviruses persisting during therapy, which is highly genetically stable over time. [PDF]
J VirolShahid A +22 more
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Biotechnology and Genetic Engineering Reviews, 2018
Impressive advances have been made in the treatment and management of HIV-1 infected individuals. Combination antiretroviral therapy (cART) has turned HIV-1 infection from an almost invariable deadly infectious disease, to a lifelong manageable infectious disease. However, a cure or vaccine has not been forthcoming.
Guido, van Marle +3 more
openaire +2 more sources
Impressive advances have been made in the treatment and management of HIV-1 infected individuals. Combination antiretroviral therapy (cART) has turned HIV-1 infection from an almost invariable deadly infectious disease, to a lifelong manageable infectious disease. However, a cure or vaccine has not been forthcoming.
Guido, van Marle +3 more
openaire +2 more sources
Understanding HIV Compartments and Reservoirs
Current HIV/AIDS Reports, 2014The spectrum of HIV-1 cellular reservoirs is highly diversified, and their role varies according to the milieu of the anatomical sites in which the virus replicates. In this light, mechanisms underlying HIV-1 persistence in anatomical compartments may be profoundly different from what is observed in peripheral blood.
SVICHER, VALENTINA +4 more
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HIV-1 subtypes and latent reservoirs
Current Opinion in HIV and AIDS, 2023Purpose of review We explore the current status of research on HIV-1 subtype-specific variations and their impact on HIV-1 latency. We also briefly address the controversy surrounding the decision-making process governing the ON/OFF states of HIV-1 transcription, specifically focusing on the regulatory elements, the long ...
Udaykumar, Ranga +2 more
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Current Opinion in Infectious Diseases, 1999
Combination therapy for HIV-1 infection can reduce viremia to undetectable levels, suggesting that prolonged treatment might eradicate the infection. However, one potential mechanism for viral persistence involves the establishment of a state of latent infection.
J, Blankson, D, Persaud, R F, Siliciano
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Combination therapy for HIV-1 infection can reduce viremia to undetectable levels, suggesting that prolonged treatment might eradicate the infection. However, one potential mechanism for viral persistence involves the establishment of a state of latent infection.
J, Blankson, D, Persaud, R F, Siliciano
openaire +2 more sources
Clinics in Laboratory Medicine, 2002
In most infected individuals, HIV-1 replicates high levels throughout the duration of infection, including the clinically quiescent phase of disease. The level of this active viral replication correlates directly with disease progression and survival.
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In most infected individuals, HIV-1 replicates high levels throughout the duration of infection, including the clinically quiescent phase of disease. The level of this active viral replication correlates directly with disease progression and survival.
openaire +2 more sources
Current HIV/AIDS Reports, 2012
In the past few years, major advances have been achieved in understanding the nature and the maintenance mechanisms of the HIV reservoir. Although antiretroviral therapy works well in a majority of patients, it faces problems of compliance, resistance, toxicity, and cost.
openaire +2 more sources
In the past few years, major advances have been achieved in understanding the nature and the maintenance mechanisms of the HIV reservoir. Although antiretroviral therapy works well in a majority of patients, it faces problems of compliance, resistance, toxicity, and cost.
openaire +2 more sources