Results 161 to 170 of about 36,601 (210)

In-depth Analysis of the HIV Reservoir Confirms Effectiveness and Safety of Dolutegravir/Lamivudine in a Phase 4 Randomized Controlled Switch Trial (RUMBA). [PDF]

J Infect Dis
De Scheerder MA, Degroote S, Delporte M, Kiselinova M, Trypsteen W, Vincke L, De Smet E, Van Den Eeckhout B, Schrooyen L, Verschoore M, Muccini C, Vanherrewege S, Caluwe E, De Buyser S, Gerlo S, Blomme E, Vandekerckhove L.   +16 more
europepmc   +1 more source

Quantifying the HIV reservoir with dilution assays and deep viral sequencing. [PDF]

Biometrics
Lotspeich SC, Richardson BD, Baldoni PL, Enders KP, Hudgens MG.   +4 more
europepmc   +1 more source

HIV reservoir and premature aging: risk factors for aging-associated illnesses in adolescents and young adults with perinatally acquired HIV. [PDF]

PLoS Pathog
Petrara MR, Ruffoni E, Carmona F, Cavallari I, Zampieri S, Morello M, Del Bianco P, Rampon O, Cotugno N, Palma P, Rossi P, Giaquinto C, Giunco S, De Rossi A.   +13 more
europepmc   +1 more source

The reservoir of latent HIV

Frontiers in Cellular and Infection Microbiology, 2022
The persistence of latent reservoir of the human immunodeficiency virus (HIV) is currently the major challenge in curing HIV infection. After HIV infects the human body, the latent HIV is unable to be recognized by the body’s immune system. Currently, the widely adopted antiretroviral therapy (ART) is also unble to eliminate it, thus hindering the ...
Dexi Chen, Chuanyun Li
exaly   +4 more sources

Measuring the HIV-1 reservoir [PDF]

Nature Reviews Microbiology, 2019
The description of a method to measure the HIV-1 reservoir that quantifies intact and defective proviruses.
Andrea du Toit
exaly   +3 more sources

Peering into the HIV reservoir [PDF]

Reviews in Medical Virology, 2018
SummaryThe main obstacle to HIV eradication is the establishment of a long‐term persistent HIV reservoir. Although several therapeutic approaches have been developed to reduce and eventually eliminate the HIV reservoir, only a few have achieved promising results.
Marcial García, Norma I Rallón, José M Benito   +2 more
exaly   +3 more sources

HIV reservoirs and latency models

Virology, 2011
The main impediment to a cure for HIV is the existence of long-lasting treatment resistant viral reservoirs. In this review, we discuss what is currently known about reservoirs, including their formation and maintenance, while focusing on latently infected CD4+ T cells.
Una O’Doherty, Erin H Graf
exaly   +3 more sources

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Combatting the HIV reservoir

Nature Reviews Microbiology
Agustina Taglialegna
exaly   +3 more sources

Combating the HIV reservoirs

Biotechnology and Genetic Engineering Reviews, 2018
Impressive advances have been made in the treatment and management of HIV-1 infected individuals. Combination antiretroviral therapy (cART) has turned HIV-1 infection from an almost invariable deadly infectious disease, to a lifelong manageable infectious disease. However, a cure or vaccine has not been forthcoming.
Guido, van Marle, Deirdre L, Church, Frank, van der Meer, M John, Gill   +3 more
openaire   +2 more sources