Results 101 to 110 of about 1,155,481 (241)

Fluvastatin Plus Dipyridamole Suppresses Canine Hemangiosarcoma Growth in Patient‐Derived Xenograft Models Through Lactate Dehydrogenase‐Associated Cholesterol/Lipid Metabolism

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Tumour cells commonly exhibit aerobic glycolysis and produce lactate despite oxygen availability. Lactate dehydrogenase (LDH) catalyses pyruvate‐lactate interconversion and regulates intracellular lactate levels. Endothelial cells also depend on glycolysis for ATP production, which prompted us to investigate LDH in canine hemangiosarcoma (HSA),
Tamami Suzuki, Suzune Tanaka, Keika Kishimoto, Takuma Goto, Jumpei Yamazaki, Takashi Kimura, Keisuke Aoshima   +6 more
wiley   +1 more source

Nonradioactive Detection of Retroviral- Associated RNase H Activity in a Microplate-Based, High-Throughput Format

BioTechniques, 2002
None of the available antiretroviral drugs that are currently used in the clinic to treat infection with HIV-1 is directed against the RNase H active site of the reverse transcriptase.
N. McLellan, X. Wei, B. Marchand, M.A. Wainberg, M. Götte   +4 more
doaj   +1 more source

HIV Drug Resistance (HIVDR) in Antiretroviral Therapy-Naïve Patients in Tanzania not Eligible for WHO Threshold HIVDR Survey is Dramatically High. [PDF]

, 2011
The World Health Organization (WHO) has recommended guidelines for a HIV drug resistance (HIVDR) survey for resource-limited countries. Eligibility criteria for patients include age below 25 years in order to focus on the prevalence of transmitted HIVDR (
Majinge, Charles, Mildner Miriam, Hartwig Klinker, Kasang Christa, Stich, August, Jacobs, Graeme Brendon, Graeme B Jacobs, Mildner, Miriam, Kalluvya, Samuel, Hensel, Irina, Gert van Zyl, Kongola Gilbert, Kalluvya Samuel, Hensel Irina, Mlewa, Mathias, Klinker, Hartwig, van Zyl, Gert, Miriam Mildner, van Zyl Gert, Christa Kasang, Mathias Mlewa, Wolfgang Preiser, Stich August, Bodem Jochen, Preiser, Wolfgang, Anne Horn, Klinker Hartwig, Eleni Koutsilieri, Kasang, Christa, Jacobs, Graeme B, Jochen Bodem, Scheller Carsten, Scheller, Carsten, Weissbrich Benedikt, Jacobs, Graeme B., Mlewa Mathias, Jacobs Graeme B., Koutsilieri, Eleni, Preiser Wolfgang, Charles Majinge, Koutsilieri Eleni, Irina Hensel, Rethwilm, Axel, Gilbert Kongola, Axel Rethwilm, Kongola, Gilbert, Horn Anne, Majinge Charles, August Stich, Horn, Anne, Bodem, Jochen, Mllewa, Mathias, Graeme B. Jacobs, Samuel Kalluvya, Carsten Scheller, Rethwilm Axel, Benedikt Weissbrich, Weissbrich, Benedikt   +57 more
core   +2 more sources

Erratum: Author correction to 'Approved HIV reverse transcriptase inhibitors in the past decade' [Acta Pharmaceutica Sinica B 12 (2022) 1567-1590]. [PDF]

Acta Pharm Sin B, 2023
Li G, Wang Y, De Clercq E.
europepmc   +1 more source

Association Between HIV Infection Duration and Left Ventricular Concentric Remodeling and Myocardial Fibrosis: A Cross‐Sectional Study Using Cardiac MRI

Journal of Magnetic Resonance Imaging, Volume 64, Issue 4, Page 1037-1049, October 2026.
ABSTRACT Background Antiretroviral therapy has transformed HIV into a chronic condition, yet cardiac injury remains a major issue. Purpose To assess the ability of cardiac MR imaging markers to predict cardiac injury and disease progression in HIV‐infected individuals. Study Type Prospective.
Chunyan Deng, Wei Sun, Tianhu Gao, Haixia Chen, Lu Liu, Ran Li   +5 more
wiley   +1 more source

Profile of etravirine in the treatment of HIV in pediatrics

Pediatric Health, Medicine and Therapeutics, 2013
Walter Dehority,1 Rolando M Viani2 1Department of Pediatrics, Division of Infectious Diseases, The University of New Mexico Health Sciences Center, University of New Mexico, Albuquerque, NM, USA; 2Department of Pediatrics, Division of Infectious Diseases,
Dehority W, Viani RM
doaj  

Approved HIV reverse transcriptase inhibitors in the past decade. [PDF]

Acta Pharm Sin B, 2022
Li G, Wang Y, De Clercq E.
europepmc   +1 more source

Thymic Involution and Function in People With HIV and General Population Controls: A Cross‐Sectional Analysis From Two Danish Cohort Studies

Aging Cell, Volume 25, Issue 10, October 2026.
Thymic involution, the age‐related replacement of thymic soft tissue by fat, has been linked to immunosenescence and chronic inflammation. Whether HIV infection affects thymic involution remains unclear. We found that people with HIV on long‐term antiretroviral therapy had more thymic tissue than controls, indicating less thymic involution. More thymic
Manon C. Vanbellinghen, Anders Boyd, Andreas Ohrt Johansen, Moises Alberto Suarez‐Zdunek, Andreas Dehlbæk Knudsen, Thomas Skårup Kristensen, Jørgen Tobias Kühl, Per Ejlstrup Sigvardsen, Michael Huy Cuong Pham, Andreas Fuchs Larsen, Klaus Fuglsang Kofoed, Børge Grønne Nordestgaard, Shoaib Afzal, Neeltje Kootstra, Susanne Dam Nielsen, Peter Reiss   +15 more
wiley   +1 more source

Characterisation of HIV‐1 Gag Cytotoxic T‐Lymphocyte Epitopes in the Southern African Region—A Systematic Review

Immunology, Volume 179, Issue 2, Page 165-184, October 2026.
Distribution of studies on HIV‐1 Gag cytotoxic T‐lymphocyte epitopes in the southern African region showing that the majority of studies (58.44%) were conducted in South Africa, followed by Botswana (15.58%), Zambia (10.39%), Malawi (7.79%), Zimbabwe (6.49%), and Angola (1.30%).
Tumelo L. Fortuin, Paballo Nkone, Shayne Loubser, Caroline T. Tiemessen, Simnikiwe H. Mayaphi   +4 more
wiley   +1 more source

Associations of severe hyperlactataemia and lactic acidosis in HIV-infected patients receiving antiretroviral theraphy [PDF]

, 2007
Includes bibliographical references (leaves 67-70).Severe symptomatic hyperlactataemia and lactic acidosis (SHLA) are life-threatening events that are occurring at increasing incidence levels in South Africa.
Osler, Meg
core   +1 more source