Results 111 to 120 of about 118,712 (218)

Approved HIV reverse transcriptase inhibitors in the past decade. [PDF]

Acta Pharm Sin B, 2022
Li G, Wang Y, De Clercq E.
europepmc   +1 more source

The Molecular Basis of Resistance Antiretroviral Markers and Polymorphisms of the Human Immunodeficiency Virus-1 Subtype Crf01-ae Protease Gene in Naïve and Treatment Failure Patients in Bali [PDF]

, 2012
Application of antiretrovirals (ARVs) in patients with Human Immunodeficiency Virus (HIV) infection has proven to reduce mortality rates and prolong life expectancy.
Budiyanti, N. S. (N), Mahardika, I. G. (I), Merati, K. T. (K), Suata, I. K. (I)   +3 more
core  

RNA interference approaches for treatment of HIV-1 infection. [PDF]

, 2015
HIV/AIDS is a chronic and debilitating disease that cannot be cured with current antiretroviral drugs. While combinatorial antiretroviral therapy (cART) can potently suppress HIV-1 replication and delay the onset of AIDS, viral mutagenesis often leads to
Bobbin, Maggie L, Burnett, John C, Rossi, John J   +2 more
core   +1 more source

The Need for Development of New HIV-1 Reverse Transcriptase and Integrase Inhibitors in the Aftermath of Antiviral Drug Resistance

Scientifica, 2012
The use of highly active antiretroviral therapy (HAART) involves combinations of drugs to achieve maximal virological response and reduce the potential for the emergence of antiviral resistance.
Mark A. Wainberg
doaj   +1 more source

HIV Reverse Transcriptase Pre-Steady-State Kinetic Analysis of Chain Terminators and Translocation Inhibitors Reveals Interactions between Magnesium and Nucleotide 3'-OH. [PDF]

ACS Omega, 2021
Dilmore CR, DeStefano JJ.
europepmc   +1 more source

Anti-HIV reverse transcriptase plant polyphenolic natural products with in silico inhibitory properties on seven non-structural proteins vital in SARS-CoV-2 pathogenesis. [PDF]

J Genet Eng Biotechnol, 2021
de Leon VNO, Manzano JAH, Pilapil DYH, Fernandez RAT, Ching JKAR, Quimque MTJ, Agbay JCM, Notarte KIR, Macabeo APG.   +8 more
europepmc   +1 more source

HIV reverse transcriptase [PDF]

Science-Business eXchange, 2010
openaire   +3 more sources

Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection [PDF]

, 2003
Although the pathogenesis of human immunodeficiency virus (HIV) infection and the general virologic and immunologic principles underlying the use of antiretroviral therapy are similar for all HIV-infected persons, there are unique considerations needed ...
Antiretroviral Therapy and Medical Management of HIV-Infected Children, ATMMHC, Health Resources and Services Administration, HRSA, National Institutes of Health, NIH, National Pediatric and Family HIV Resource Center, NPHRC   +3 more
core  

HIV drug resistance in children and adolescents on NNRTI-based antiretroviral therapy and subsequent virologic response to dolutegravir-based regimens in Ghana

AIDS Research and Therapy
HIV drug resistance (HIVDR) was retrospectively characterized among 20 children and adolescents with HIV with virologic failure on non-nucleoside reverse transcriptase inhibitor (NNRTI)-based therapy, and virologic response in those switched to ...
Adwoa K.A Afrane, Vlad Novitsky, Joel Hague, Kwamena Sagoe, Yakubu Alhassan, Joycelyn Assimeng Dame, Charles Martyn-Dickens, Margaret Lartey, Bamenla Goka, Kwasi Torpey, Rami Kantor, Awewura Kwara   +11 more
doaj   +1 more source

Structure of HIV reverse transcriptase [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 1993
J. Wang, S. J. Smerdon, L. A. Kohlstaedt, J. Jacger, P. A. Rice, J. M. Friedman, T. A. Steitz   +6 more
openaire   +1 more source