Results 141 to 150 of about 73,667 (245)

Small Conformational Changes Underlie Evolution of Resistance to NNRTI in HIV Reverse Transcriptase. [PDF]

Biophys J, 2020
Srivastava A, Birari V, Sinha S.
europepmc   +1 more source

Mechanism of lipid disorder in HIV infection: apolipoprotein-B kinetics, fat distribution, insulin resistance and adipocytokines in patients taking protease inhibitors or non-nucleoside reverse transcriptase inhibitors [PDF]

, 2010
The relationship between antiretroviral treatment of HIV infection, body fat distribution, insulin resistance (HOMA), adipocytokine and apolipoprotein-B (apoB) kinetics was investigated in 12 HIV negative controls and 55 HIV-infected patients including ...
Das, Satyajit
core  

Structure of HIV reverse transcriptase [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 1993
J. Wang, S. J. Smerdon, L. A. Kohlstaedt, J. Jacger, P. A. Rice, J. M. Friedman, T. A. Steitz   +6 more
openaire   +1 more source

Detection of HIV-1 Resistance Mutations to Antiretroviral Therapy and Cell Tropism in Russian Patients Using Next-Generation Sequencing

Pathogens
The use of antiretroviral therapy (ART) as the only effective way to control human immunodeficiency virus (HIV) infection results in HIV drug resistance.
Artem Fadeev, Veronika Eder, Maria Pisareva, Valery Tsvetkov, Alexey Masharskiy, Kseniya Komissarova, Anna Ivanova, Nikita Yolshin, Andrey Komissarov, Alexey Mazus, Dmitry Lioznov   +10 more
doaj   +1 more source

Click Chemistry-Based Two-Component System for Efficient Inhibition of Human Immunodeficiency Virus (HIV) Reverse Transcriptase (RT). [PDF]

ACS Omega, 2020
Ledezma CE, Cornett EM, Kolpashchikov DM.   +2 more
europepmc   +1 more source

Respiratory chain dysfunction associated with multiple mitochondrial DNA deletions in antiretroviral therapy-related lipodystrophy. [PDF]

, 2013
Highly-active antiretroviral therapy (HAART) can induce a characteristic lipodystrophy syndrome characterized by peripheral fat wasting and central adiposity, usually associated with hyperlipidaemia and insulin resistance [1,2].
Miró, Òscar, Cardellach, Francesc, Pedrol, Enric, Nunes Martínez, Virginia, Casademont i Pou, Jordi, Miró i Andreu, Òscar, Gómez, Montserrat   +6 more
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Exploring the Reaction Mechanism of HIV Reverse Transcriptase with a Nucleotide Substrate. [PDF]

J Phys Chem B, 2020
Wang H, Huang N, Dangerfield T, Johnson KA, Gao J, Elber R.   +5 more
europepmc   +1 more source

Predictors of immunological failure after initial response to highly active antiretroviral therapy in HIV-1-infected adults: A EuroSIDA study [PDF]

, 2004
BACKGROUND: Factors that determine the immunological response to highly active antiretroviral therapy (HAART) are poorly defined. OBJECTIVE: Our aim was to investigate predictors of immunological failure after initial CD4(+) response.
Horban, A, Mocroft, Amanda, Dragsted, Ulrik Bak, Vella, S, Viard, JP, Lundgren, JD, Vella, Stefano, Viard, Jean-Paul, Machala, Ladislav, Hansen, ABE, Panos, G, Horban, Andrzej, Panos, George, Dragsted, UB, Lundgren, Jens Dilling, Mercey, D, Mocroft, A, Hansen, Ann-Britt E, Machala, L, Mercey, Danielle   +19 more
core  

Assessing subtypes and drug resistance mutations among HIV-1 infected children who failed antiretroviral therapy in Kelantan, Malaysia

Brazilian Journal of Infectious Diseases
Antiretroviral (ARV) therapy has dramatically reduced morbidity and mortality in human immunodeficiency virus 1 (HIV-1) infected children. However, development of ARV resistance in these children is a major public health problem due to lack of ...
Suharni Mohamad, Zakuan Zainy Deris, Nik Khairulddin Yusoff, Tg Ahmad Akram Tg Mohd Ariffin, Rafidah Hanim Shueb   +4 more
doaj   +1 more source

3-Hydroxypyrimidine-2, 4-dione Derivatives as HIV Reverse Transcriptase-Associated RNase H Inhibitors: QSAR Analysis and Molecular Docking Studies. [PDF]

Iran J Pharm Res, 2020
Mostoufi A, Chamkouri N, Kordrostami S, Alghasibabaahmadi E, Mojaddami A.   +4 more
europepmc   +1 more source