Results 81 to 90 of about 63,834 (200)

Avoiding Drug Resistance in HIV Reverse Transcriptase. [PDF]

Chem Rev, 2021
Cilento ME, Kirby KA, Sarafianos SG.
europepmc   +1 more source

Discovery of miRNAs unique to actively transcribed erythroparvovirus infection in heart failure patients

ESC Heart Failure, Volume 12, Issue 3, Page 1872-1882, June 2025.
Abstract Aims miRNAs, small non‐coding RNAs, play key roles in gene regulation, cell differentiation and tissue development. They influence viral infection outcomes by directly interacting with viral genomes or modifying the host microenvironment. This study demonstrates miRNAs' ability to selectively suppress transcriptionally active erythroparvovirus,
Ganna Aleshcheva, Sara Salih, Christian Baumeier, Felicitas Escher, C. Thomas Bock, Heinz‐Peter Schultheiss   +5 more
wiley   +1 more source

Advances in the Role of Antimicrobial Peptides in the Management of Sexually Transmitted Infections

Journal of Clinical Laboratory Analysis, Volume 39, Issue 11, June 2025.
The article reviews recent advancements in the use of antimicrobial peptides (AMPs) for the treatment and prevention of sexually transmitted infections (STIs), with a particular focus on research progress in combating infections such as gonorrhea, HIV, HSV, and Chlamydia, as well as the challenges and future directions in this field.
Shuangwen Xiao, Wei Zuo, Qing Xiang, Yafeng Xie, Yongjian Xiao   +4 more
wiley   +1 more source

Profile of etravirine in the treatment of HIV in pediatrics

Pediatric Health, Medicine and Therapeutics, 2013
Walter Dehority,1 Rolando M Viani2 1Department of Pediatrics, Division of Infectious Diseases, The University of New Mexico Health Sciences Center, University of New Mexico, Albuquerque, NM, USA; 2Department of Pediatrics, Division of Infectious Diseases,
Dehority W, Viani RM
doaj  

Analytical treatment interruption among women with HIV in southern Africa who received VRC01 or placebo in the Antibody Mediated Prevention Study: ATI stakeholder engagement, implementation and early clinical data

Journal of the International AIDS Society, Volume 28, Issue 6, June 2025.
Abstract Introduction Antiretroviral therapy (ART) prevents and treats, but does not eradicate, HIV. Early ART initiation is associated with post‐ART virologic control, particularly among African women, and anti‐HIV‐1 broadly neutralizing antibodies (bnAbs) may modulate immune responses to HIV.
Shelly Karuna, Fatima Laher, Sufia Dadabhai, Pei‐Chun Yu, Doug Grove, Catherine Orrell, Joseph Makhema, Mina C. Hosseinipour, Carrie‐Anne Mathew, William Brumskine, Nyaradzo Mgodi, Philip Andrew, Lucio Gama, Carissa Karg, Gail Broder, Kagisho Baepanye, Jonathan Lucas, Michele Andrasik, Simbarashe Takuva, Manuel Villaran, Azwidihwi Takalani, Randall Tressler, Lydia Soto‐Torres, Amanda S. Woodward Davis, Ames Dhai, Ian M. Sanne, Myron S. Cohen, Lawrence Corey, Glenda Gray, Allan C. deCamp, Katharine J. Bar   +30 more
wiley   +1 more source

Point of care testing of HIV in children younger than 18 months with three different HIV virological assays. Experience from a district hospital in a resource-limited setting

Microbiology Research, 2012
Diagnosis of HIV in children younger than 18 months can be challenging in developing countries because requires the use of HIV virological tests. In this study we describe the experience with three commercial assays, HIV- 1 DNA polymerase chain reaction (
Gerardo Alvarez-Uria, Jose M. Azcona, Srinivasulu Reddy, Manoranjan Midde, Praveen K. Naik, N. Raghuprakash Reddy   +5 more
doaj   +1 more source

HIV Reverse Transcriptase Pre-Steady-State Kinetic Analysis of Chain Terminators and Translocation Inhibitors Reveals Interactions between Magnesium and Nucleotide 3'-OH. [PDF]

ACS Omega, 2021
Dilmore CR, DeStefano JJ.
europepmc   +1 more source

Reverse transcriptase inhibitors in Aicardi–Goutières syndrome: A crossover clinical trial

Developmental Medicine &Child Neurology, Volume 67, Issue 6, Page 750-757, June 2025.
Viral nucleic acid recognition induces a physiological type I interferon mediated innate immune response. In some cases of Aicardi‐Goutières syndrome, this same response is proposed to be triggered by self‐derived nucleic acid generated through reverse transcription. Here, reverse transcriptase inhibitors were assessed in such cases.
Yanick J. Crow, Tracy A. Briggs, Despina Eleftheriou, Amitav Parida, Claire Battison, Annabel Giddings, Titouan Kennel, Richard A. Parker, AGS‐RTIs Study Group, Aimee Donald, Paddy Mcmaster, Jay Shetty, Katherine Jack, Alan J Quigley, Alice Burleigh, Felice D’Arco, Cheryl Hemingway, Ying Hong, Elena Moraitis, Fiona Price‐Kuehne, Annapurna Sudarsanam, Evangeline Wassmer, Katie Livingstone, Fraser JH Sutherland, Marie‐Thérèse El‐Daher, John Norrie, Hannah Ensor, Alison F Munro, Lee Murphy, Alan Maclean, Katy R Reid, Deborah Forbes, Vincent Bondet, Darragh Duffy, David PJ Hunt, Gillian I Rice   +35 more
wiley   +1 more source

Anti-HIV reverse transcriptase plant polyphenolic natural products with in silico inhibitory properties on seven non-structural proteins vital in SARS-CoV-2 pathogenesis. [PDF]

J Genet Eng Biotechnol, 2021
de Leon VNO, Manzano JAH, Pilapil DYH, Fernandez RAT, Ching JKAR, Quimque MTJ, Agbay JCM, Notarte KIR, Macabeo APG.   +8 more
europepmc   +1 more source

Premature strand transfer by the HIV-1 reverse transcriptase during strong-stop DNA synthesis [PDF]

, 1994
Bep Klaver, Ben Berkhout
openalex   +1 more source