Results 81 to 90 of about 118,238 (222)
Química Nova, 2003 Currently available anti-HIV drugs can be classified into three categories: nucleoside analogue reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (PIs).
Marcus Vinícius Nora de Souza +1 more
doaj +1 more source
Optimization of diarylazines as anti-HIV agents with dramatically [PDF]
, 2013 Non-nucleoside inhibitors of HIV-1 reverse transcriptase are reported that have ca. 100-fold greater solubility than the structurally related drugs etravirine and rilpivirine, while retaining high anti-viral activity.
Anderson, Karen S. +4 more
core +1 more source
HIV Medicine, EarlyView.Abstract Aim This study compared acute psychological responses to a single session of low‐volume high‐intensity interval exercise (HIIE‐LV), high‐volume high‐intensity interval exercise (HIIE‐HV), and moderate‐intensity continuous exercise (MICE) in people living with HIV, and healthy controls using a randomized, counterbalanced crossover design ...
Phelipe Wilde +9 more
wiley +1 more source
HIV Medicine, EarlyView.Abstract Introduction A proportion of people living with HIV (PLWH) fail to restore their CD4 count or their CD4/CD8 ratio despite effective antiretroviral therapy (ART). PLWH with immune non‐response (INR) are at a higher risk of both AIDS and non‐AIDS events. The underlying mechanisms of INR remain unclear.
Charlotte Silvestre +2 more
wiley +1 more source
Primary HIV Drug Resistance among Recently Infected Cases of HIV in North-West India
AIDS Research and Treatment, 2019 Background. Antiretroviral treatment may lead to the emergence of HIV drug resistance, which can be transmitted. HIV primary drug resistance (PDR) is of great public health concern because it has the potential to compromise the efficacy of antiretroviral
C. K. Chauhan +5 more
doaj +1 more source
Proceedings, 2017 Reverse transcriptase (RT), the key enzyme in the HIV life cycle of HIV, is one of the main targets for the antiretroviral chemotherapy. [...]
Kaijun Jin +4 more
doaj +1 more source
Low prevalence of hepatitis C co-infection in recently HIV-infected minority men who have sex with men in Los Angeles: a cross-sectional study. [PDF]
, 2015 BackgroundGeographic and sociodemographic characterization of hepatitis C virus (HCV) transmission amongst men who have sex with men (MSM) has been limited.
Bhattacharya, Debika +7 more
core +2 more sources
Emerging reverse transcriptase inhibitors for HIV-1 infection [PDF]
Expert Opinion on Emerging Drugs, 2018 There are 36.7 million people living with HIV with 20.9 million having access to antiretroviral therapy (ART). Nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) remain the 'backbone' of ART. However, the currently available nine NRTIs and five non-nucleoside reverse transcriptase inhibitors (NNRTIs) have significant side effects and ...
Mohammad A, Rai +2 more
openaire +2 more sources
HIV Medicine, EarlyView.Abstract Introduction Long‐acting injectable antiretroviral therapy (ART) with Cabotegravir (CAB) and Rilpivirine (RPV) offers an alternative to daily oral regimens, improving adherence and patient satisfaction. However, its impact on body composition and metabolism remains underexplored.
Andrea De Vito +13 more
wiley +1 more source
Mechanism of polypurine tract primer generation by HIV-1 reverse transcriptase [PDF]
, 2018 HIV-1 reverse transcriptase (HIV-1 RT) possesses both DNA polymerase activity and RNase H activity that act in concert to convert single-stranded RNA of the viral genome to double-stranded DNA that is then integrated into the DNA of the infected cell ...
Figiel, Małgorzata +8 more
core +1 more source