Results 11 to 20 of about 4,770 (153)

Hiwi Promotes the Proliferation of Colorectal Cancer Cells via Upregulating Global DNA Methylation [PDF]

open access: yesDisease Markers, Volume 2015, Issue 1, 2015., 2015
Hiwi is well known for its role in stem cell renewal, maintaining the resting stage, and downregulating cell cycle of stem cells via RNA silencing. And Hiwi overexpression has been recognized in several types of cancers. In the present study, we examined the Hiwi expression in colorectal cancer (CRC) specimens in both mRNA and protein levels via real ...
Lin Yang   +7 more
wiley   +3 more sources

Estimating fertility using adults: A method for under‐enumerated pre‐adult skeletal samples

open access: yesAmerican Journal of Biological Anthropology, Volume 181, Issue 2, Page 262-270, June 2023., 2023
Abstract Objectives Infant underrepresentation poses a great risk to accurate palaeodemographic findings when analyzing skeletal samples. Empirically derived palaeodemographic methods all require unbiased or minimally biased pre‐adult representation for estimating demographic characteristics, including fertility.
Bonnie R. Taylor   +2 more
wiley   +1 more source

A low‐complexity transmit combining method for downlink of massive multiuser multiple input multiple output systems

open access: yesElectronics Letters, Volume 59, Issue 10, May 2023., 2023
In this paper, a low‐complexity transmit combining scheme for the massive MU‐MIMO systems with time division duplex si proposed, devised in a similar manner as the well‐known Tomlinson‐Harashima precoding (THP) scheme. In order to suppress multiuser interference with a lower computational complexity we here employ the Gram‐Schmidt orthogonalization ...
Rade P. Dabetic, Goran B. Markovic
wiley   +1 more source

Attenuation of Piwil2 induced by hypoxic postconditioning prevents cerebral ischemic injury by inhibiting CREB2 promoter methylation

open access: yesBrain Pathology, Volume 33, Issue 1, January 2023., 2023
Schematic depicting mechanism by which HPC protects neurons against tGCI in CA1 through Piwil2‐mediated epigenetics. Abstract Epigenetic modification contributes to the pathogenesis of cerebral ischemia. Piwil2 belongs to the PIWI proteins subfamily and has a key role in the regulation of gene transcription through epigenetics.
Lixuan Zhan   +8 more
wiley   +1 more source

Upper Troposphere Smoke Injection From Large Areal Fires

open access: yesJournal of Geophysical Research: Atmospheres, Volume 126, Issue 23, 16 December 2021., 2021
Abstract Large areal fires, such as those ignited following a nuclear detonation, can inject smoke into the upper troposphere and lower stratosphere. Detailed fire simulations allow for assessment of how local weather interacts with these fires and affects smoke lofting.
Stephanie Redfern   +5 more
wiley   +1 more source

Vision Mātauranga research directions: opportunities for iwi and hapū management plans

open access: yesKōtuitui: New Zealand Journal of Social Sciences Online, Volume 16, Issue 2, Page 371-383, November 2021., 2021
ABSTRACT The Ministry of Business, Innovation and Employment (MBIE) Vision Mātauranga policy has created a clear message for researchers in Aotearoa/New Zealand – that research conducted in Aotearoa New Zealand should recognise and support the ‘unlocking of the innovative potential of Māori for the benefit of all New Zealand’ and be designed with a ...
Lucy H. Kaiser, Wendy S. A. Saunders
wiley   +1 more source

The obstetrical dilemma hypothesis: there's life in the old dog yet

open access: yesBiological Reviews, Volume 96, Issue 5, Page 2031-2057, October 2021., 2021
ABSTRACT The term ‘obstetrical dilemma’ was coined by Washburn in 1960 to describe the trade‐off between selection for a larger birth canal, permitting successful passage of a big‐brained human neonate, and the smaller pelvic dimensions required for bipedal locomotion. His suggested solution to these antagonistic pressures was to give birth prematurely,
Martin Haeusler   +5 more
wiley   +1 more source

Are fathers a good substitute for mothers? Paternal care and growth rates in Shodagor children

open access: yesDevelopmental Psychobiology, Volume 63, Issue 6, September 2021., 2021
Abstract Biparental care is a hallmark of human social organization, though paternal investment varies between and within societies. The facultative nature of paternal care in humans suggests males should invest when their care improves child survival and/or quality, though testing this prediction can be challenging because of the difficulties of ...
K. E. Starkweather   +5 more
wiley   +1 more source

Elevated P‐Element‐Induced Wimpy‐Testis‐Like Protein 1 Expression Predicts Unfavorable Prognosis for Patients with Various Cancers

open access: yesJournal of Oncology, Volume 2021, Issue 1, 2021., 2021
Increasing evidence has shown that overexpression of P‐element‐induced wimpy‐testis (PIWI)‐like protein 1 (PIWIL1) was associated with unfavorable prognosis of patients with various types of cancers. Herein, we conducted this meta‐analysis to identify the clinicopathological and prognostic value of the PIWIL1 expression in cancers.
Kehua Jiang   +7 more
wiley   +1 more source

Overexpression of Hiwi Promotes Growth of Human Breast Cancer Cells [PDF]

open access: yesAsian Pacific Journal of Cancer Prevention, 2014
The Piwi subfamily comprises two argonaute (Ago) family proteins, which are defined by the presence of PAZ and Piwi domains, with well known roles in RNA silencing. Hiwi, a human Piwi subfamily member, has been shown to play essential roles in stem cell self-renewal and gametogenesis.
Da-Wei, Wang   +4 more
openaire   +2 more sources

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