Results 11 to 20 of about 82 (80)
HLA B‐27 Subtypes in Turkish Patients with Spondyloarthropathy and Healthy Controls [PDF]
Disease Markers, Volume 20, Issue 6, Page 309-312, 2004., 2004 The frequency and the distribution of HLA‐B27 subtypes in spondylarthropathy (SpA) patients and controls were investigated in a sample Turkish population. B27 subtyping was performed by PCR‐SSP method in two groups: 49 unrelated HLA‐B27 positive Turkish patients with the diagnosis of SpA according to the European Spondyloarthropathy Study Group ...
Fatma Savran Oguz +8 more
wiley +4 more sources
Spondyloarthritis and the Human Leukocyte Antigen (HLA)-B*27 Connection [PDF]
Frontiers in Immunology, 2021 Heritability of Spondyloarthritis (SpA) is highlighted by several familial studies and a high association with the presence of human leukocyte antigen (HLA)-B*27. Though it has been over four decades since the association of HLA-B*27 with SpA was first determined, the pathophysiological roles played by specific HLA-B*27 allotypes are not fully ...
Chengappa G. Kavadichanda +4 more
openaire +3 more sources
Association of Protective HLA-A With HLA-B∗27 Positive Ankylosing Spondylitis [PDF]
Frontiers in Genetics, 2021 ObjectivesTo further elucidate the role of the MHC in ankylosing spondylitis by typing 17 genes, searching for HLA-B∗27 independent associations and assessing the impact of sex on this male biased disease.MethodsHigh-confidence two-field resolution genotyping was performed on 310 cases and 2196 controls using an n-1 concordance method.
Jessika Nordin +18 more
openaire +5 more sources
HLA-B*27 is associated with CNO in a European cohort
Pediatric Rheumatology, 2023 Abstract Objectives To determine the influence of HLA-B27 positivity on risk of developing chronic nonbacterial osteomyelitis (CNO). Methods HLA-B*27 genotype was assessed in 3 European CNO populations and compared with local control populations (572 cases, 33,256 controls).
Daire O’Leary +8 more
openaire +4 more sources
A case of familial Mediterranean fever presenting with ankylosing spondylitis: A rare case‐report
Clinical Case Reports, Volume 11, Issue 11, November 2023., 2023 Key Clinical Message The association of familial Mediterranean fever and ankylosing spondylitis is rare, but it is essential to consider this diagnosis in patients with a history of FMF who develop symptoms of back pain or other rheumatologic conditions.
Amirreza Khalaji, Mehdi Jafarpour
wiley +1 more source
Rheumatology &Autoimmunity, Volume 2, Issue 1, Page 15-21, March 2022., 2022 Abstract Objectives To determine the association of Human leukocyte antigen B (HLA‑B) alleles with ankylosing spondylitis and the allelic association of HLA‐B27 with endoplasmic reticulum aminopeptidase 1 (ERAP1) single‐nucleotide polymorphism (SNP) rs30187 in patients with ankylosing spondylitis (AS).
Md Kamrul H. Sajib +7 more
wiley +1 more source
Predominant frequency of HLA‐B*27 in patients with ankylosing spondylitis in southeastern China
Immunity, Inflammation and Disease, Volume 9, Issue 4, Page 1696-1701, December 2021., 2021 Abstract Objectives This study was to investigate the polymorphism and distribution of alleles of HLA‐B*27 in patients with ankylosing spondylitis (AS) in Han population of southeastern China. Methods A total of 89 peripheral blood samples from southeastern Chinese Han patients with AS that diagnosed according to Modified New York criteria were ...
JiaoJiao Lu +7 more
wiley +1 more source
Optimization of HLA-B*27 ALLELE Genotyping by PCR-SSP [PDF]
Clinics, 2020 HLA-B27 is strongly associated with ankylosing spondylitis (AS) and its presence helps to confirm AS diagnosis. Due to the high HLA polymorphism and the differentiated contribution of alleles and molecules encoded by them, HLA-B*27 allele identification is relevant in the clinical follow-up, diagnosis, and treatment of this spondyloarthropathy ...
Fernanda Formaggi Lara-Armi +8 more
openaire +4 more sources
SAT0033 TCR REPERTOIRE PROFILING OF SYNOVIAL FLUID OF HLA-B*27+ AND HLA-B*27- PATIENTS WITH PSORIATIC ARTHRITIS [PDF]
Annals of the Rheumatic Diseases, 2019 Background: Diagnosis of psoriatic arthritis (PsA) is primarily based on clinical phenotype because of the diversity of the associated features [1]. The heterogeneity likely implies different mechanisms of the disease progression or initiation. Certain HLA alleles have been shown as risk factors for different spondyloarthropathies (SpAs), implying ...
Ekaterina Komech +5 more
openaire +1 more source
The Kaohsiung Journal of Medical Sciences, Volume 36, Issue 6, Page 441-449, June 2020., 2020 Abstract Although human leucocyte antigen (HLA)‐B27 is strongly associated with ankylosing spondylitis (AS), the association of unfolded protein response (UPR) induced by HLA‐B27 misfolding in AS remains controversial. Since dendritic cells (DCs) are crucial in induction of AS in HLA‐B27‐transgenic rats, and plasmacytoid DCs (pDCs) belong to one type ...
Chin‐Hsiu Liu +13 more
wiley +1 more source