Results 31 to 40 of about 82 (80)
Frequency of the New HLA‐B*2709 Allele in Ankylosing Spondylitis Patients and Healthy Individuals
, 1994 Disease Markers, Volume 12, Issue 3, Page 215-217, 1994.
Mauro D’Amato +5 more
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Optimization of an in-house PCR method for the detection of HLA-B*27 alleles
Biomedical Reports, 2018 The association of spondyloarthropathies with different alleles of human leukocyte antigen (HLA) B*27 is well established. Different subtypes of HLA-B*27 may be linked with different ethnic groups, distinct clinical manifestations, specific age of onset and different prognoses.
Noor, Afshan +3 more
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Increased Conformational Flexibility of HLA–B*27 Subtypes Associated With Ankylosing Spondylitis [PDF]
Arthritis & Rheumatology, 2016 ObjectiveDissimilarities in antigen processing and presentation are known to contribute to the differential association of HLA–B*27 subtypes with the inflammatory rheumatic disease ankylosing spondylitis (AS). In support of this notion, previous x‐ray crystallographic data showed that peptides can be displayed by almost identical HLA–B*27 molecules in ...
Bernhard Loll +6 more
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A Common Minimal Motif for the Ligands of HLA-B*27 Class I Molecules
PLoS ONE, 2014 CD8(+) T cells identify and kill infected cells through the specific recognition of short viral antigens bound to human major histocompatibility complex (HLA) class I molecules. The colossal number of polymorphisms in HLA molecules makes it essential to characterize the antigen-presenting properties common to large HLA families or supertypes.
Barriga, Alejandro +5 more
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A Case of Undifferentiated Spondyloarthropathy- HLA B 27 Positive
International Journal of Innovative Science and Research Technology (IJISRT)Undifferentiated arthritis / Undifferentiated spondyloarthropathy are terms used to describe inflammatory arthritis which has not differentiated into a specific rheumatic disease . UA can either describe a patient of early onset rheumatic disease who might progress to specific rheumatic disorder or describe patients who fail to differentiate into ...
Mohanakrishnan . +2 more
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Distribution of HLA-B*27 Subtypes in Patients with Ankylosing Spondylitis in Local Population
Journal of the College of Physicians and Surgeons Pakistan, 2019 To compare the distribution of HLA-B*27 subtypes in healthy controls and in ankylosing spondylitis (AS) patients of different ethnic groups from Pakistan.Descriptive study.Armed Forces Institute of Pathology, Rawalpindi, Pakistan, from April 2016 to October 2017.Forty-nine HLA-B*27 positive, unrelated AS patients and 18 HLA-B*27 positive healthy BMT ...
Noor Afshan, Lodhi +3 more
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[Reiter's disease and HLA-B 27].
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1979 K O, Skavdal, B G, Solheim
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The enigmatic role of HLA-B*27 in spondyloarthritis pathogenesis
Seminars in Immunopathology, 2021Establishing a clear role for HLA-B*27 in the pathogenesis of spondyloarthritis continues to be challenging. Aberrant properties of the heavy chain as well as a potential role presenting arthritogenic peptides continue to be pursued as plausible mechanisms. Recent studies implicate HLA-B*27 in aberrant bone formation.
Fatemeh Navid +2 more
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The role of HLA-B*27 in spondyloarthritis
Best Practice & Research Clinical Rheumatology, 2017The mechanism by which HLA-B*27 predisposes to spondyloarthritis remains unresolved. Arthritogenic peptides have not been defined in humans and are not involved in experimental models of spondyloarthritis. Aberrant properties of HLA-B*27 can activate the IL-23/IL-17 axis in HLA-B*27 transgenic rats and humans.
Robert A, Colbert +2 more
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