Results 121 to 130 of about 16,215 (178)
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Clinical Rheumatology, 1996
Most HLA-B27 positive individuals live without noticing the risk factor they carry. Only when certain bacteria come into play, usually in the form of intestinal or genital infection, some of the HLA-B27 positive individuals will develop a reactive disease.
J, Uksila, P, Toivanen
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Most HLA-B27 positive individuals live without noticing the risk factor they carry. Only when certain bacteria come into play, usually in the form of intestinal or genital infection, some of the HLA-B27 positive individuals will develop a reactive disease.
J, Uksila, P, Toivanen
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Rheumatology, 1988
The various subtypes of HLA-B27 are described together with their worldwide distribution. None is uniquely related to AS but the evidence favours a direct role for B27 in the disease pathogenesis.
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The various subtypes of HLA-B27 are described together with their worldwide distribution. None is uniquely related to AS but the evidence favours a direct role for B27 in the disease pathogenesis.
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The Pathogenesis of HLA-B27 Arthritis: Role of HLA-B27 in Bacterial Defense
The American Journal of the Medical Sciences, 1998The way in which a host accommodates invasive facultative intracellular bacteria must be the key to the development of reactive arthritis. Investigators have analyzed the bacterial events at several levels: invasion into host cells, intracellular survival, translocation from the sites of infection to the joints, residence in the joints, and evasion of ...
M, Ikeda, D T, Yu
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Scandinavian Journal of Rheumatology, 1990
Every HLA antigen, as defined by the WHO-HLA Nomenclature, is unique. The major function of these molecules is to present antigen-peptides to the T-cell receptor, thereby contributing to the immunological defence mechanism. This function is regulated for each MHC antigen by its unique structure, with the peptide-binding pockets of the three-dimensional
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Every HLA antigen, as defined by the WHO-HLA Nomenclature, is unique. The major function of these molecules is to present antigen-peptides to the T-cell receptor, thereby contributing to the immunological defence mechanism. This function is regulated for each MHC antigen by its unique structure, with the peptide-binding pockets of the three-dimensional
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Annals of Internal Medicine, 1980
Excerpt To the editor: It is unfortunate that Dr. Calin detracts from his many excellent contributions on the importance of the HLA system in rheumatic disease (1) by concluding his recent article,...
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Excerpt To the editor: It is unfortunate that Dr. Calin detracts from his many excellent contributions on the importance of the HLA system in rheumatic disease (1) by concluding his recent article,...
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Annals of Internal Medicine, 1977
Excerpt To the editor: Esdaile, Dwosh, Urowitz, Smythe, and Falk (1) have reported in this journal a similar frequency of HLA B27 in patients with seronegative rheumatiod arthritis and a control po...
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Excerpt To the editor: Esdaile, Dwosh, Urowitz, Smythe, and Falk (1) have reported in this journal a similar frequency of HLA B27 in patients with seronegative rheumatiod arthritis and a control po...
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HLA‐B27 and the pathogenesis of spondyloarthritis
Tissue Antigens, 2002Abstract: The association of HLA‐B27 with ankylosing spondylitis and other spondyloarthropathies ranks among the strongest between any HLA antigen and a human disease. Yet, in spite of intense research and advanced knowledge of the biochemistry and biology of major histocompatibility complex molecules, the mechanism of this association remains unknown.
M, Ramos, J A, López de Castro
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HLA-B27 polymorphism in the Malays
Tissue Antigens, 2003Abstract: The frequency of HLA‐B27 and its subtypes was determined in 878 Malay subjects. Thirty‐five of the subjects typed for HLA‐A, ‐B and ‐DR were found to be positive for HLA‐B27. The frequency of this allele in the Malay population was found to be 3.99%.
J S, Dhaliwal +4 more
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Non-HLA-B27 Genetic Factors in HLA-B27 Associated Diseases
Clinical Rheumatology, 1996Family and twin studies showed that besides HLA-B27 other genetic factors are of significance for the pathogenesis of ankylosing spondylitis, reactive arthritis or acute anterior uveitis. There are up to now no strong indications that any subtype of B27 is especially associated with these diseases.
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The Lancet, 1976
Histocompatibility antigens were determined in 38 patients with frozen shoulder and 216 normal blood-donors. HLA-B27 was significantly more common in patients with frozen shoulder (42%) than in the controls (10%). The distribution of the other 19 histocompatibility antigens was similar in the patient and control groups.
D Y, Bulgen, B L, Hazleman, D, Voak
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Histocompatibility antigens were determined in 38 patients with frozen shoulder and 216 normal blood-donors. HLA-B27 was significantly more common in patients with frozen shoulder (42%) than in the controls (10%). The distribution of the other 19 histocompatibility antigens was similar in the patient and control groups.
D Y, Bulgen, B L, Hazleman, D, Voak
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