Results 21 to 30 of about 16,215 (178)

Original paper HLA-B27 detection – comparison of genetic sequence-based method and flow cytometry assay

open access: yesRheumatology, 2015
Objectives : The presence of human leukocyte antigen B27 (HLA-B27) is strongly associated with ankylosing spondylitis. HLA-B27 testing is routinely applied in the diagnosis of this disease.
Urszula Skalska   +3 more
doaj   +1 more source

HLA-B27 Negativity Is Associated With Renal Function Decline in Patients With Ankylosing Spondylitis and Secondary IgA Nephropathy

open access: yesFrontiers in Medicine, 2020
This study aimed to determine the impact of HLA-B27 on clinical phenotype and renal function during follow-up periods in patients with ankylosing spondylitis (AS) and secondary IgA nephropathy (IgAN). This single-center retrospective study included 71 AS
Ti Zhang   +5 more
doaj   +1 more source

HLA-B27 subtypes in the spondarthropathies [PDF]

open access: yesClinical and Experimental Immunology, 1993
SUMMARYThe spondartliropathy (Sp)-associated HLA-B27 antigen includes al least seven subtypes. B*2701–07, of which 01, 02, 05 and 07 occur in Caucasians. This study examined the B27 subtype distribution in British patients with Sp. The 133 HLA-B27+ subjecis comprised 94 European Caucasian Sp (58 ankylosing spondylitis (AS), 22 reactive arlhrilis (ReA ...
I L, MacLean   +6 more
openaire   +2 more sources

Human leukocyte Antigen-B*27 allele subtype prevalence and disease association of ankylosing spondylitis among south indian population

open access: yesIndian Journal of Rheumatology, 2018
Aim: Ankylosing spondylitis (AS) is a chronic inflammatory arthritis mainly affecting articular and extraarticular structures. AS clinical manifestations also involve sacroiliac joints and spine. Genetic factors play a key role in AS susceptibility.
Vikram Haridas   +6 more
doaj   +1 more source

The Rate of Helicobacter pylori Seropositivity in a Group of Korean Patients with HLA-B27-Associated Acute Anterior Uveitis. [PDF]

open access: yesPLoS ONE, 2015
To investigate an association between Helicobacter pylori seropositivity and HLA-B27-positive acute anterior uveitis (AAU) in Korean patients.Retrospective analysis was performed with data from 106 patients previously diagnosed with AAU without clinical ...
Jeong Hun Bae, Joon Mo Kim
doaj   +1 more source

Positivity and genotype distribution of HLA-B27 antigen in 7 829 patients with suspected ankylosing spondylitis

open access: yesDi-san junyi daxue xuebao, 2020
Objective To analyze the positivity of human leukocyte surface antigen-B27 (HLA-B27) in patients with suspected ankylosing spondylitis (AS) and their relatives in Chongqing to understand the gender-specific distribution of HLA-B27 genotypes in the ...
GAO Lenyu   +3 more
doaj   +1 more source

Microarray Analysis of Response of Salmonella during Infection of HLA-B27- Transfected Human Macrophage-Like U937 Cells

open access: yesBMC Genomics, 2010
Background Human leukocyte antigen (HLA)-B27 is strongly associated with the development of reactive arthritis (ReA) in humans after salmonellosis. Human monocytic U937 cells transfected with HLA-B27 are less able to eliminate intracellular Salmonella ...
Hinton Jay CD   +4 more
doaj   +1 more source

Ultrasonographic assessment of enthesitis in HLA-B27 positive patients with rheumatoid arthritis, a matched case-only study. [PDF]

open access: yesPLoS ONE, 2013
INTRODUCTION: HLA-B27 has a modifier effect on the phenotype of multiple diseases, both associated and non-associated with it. Among these effects, an increased frequency of clinical enthesitis in patients with Rheumatoid Arthritis (RA) has been reported
Antonio Mera-Varela   +5 more
doaj   +1 more source

Comparison of Clinical Features in HLA-B27 Positive and Negative Patients With Axial Spondyloarthritis: Results From a Cohort of 4,131 Patients

open access: yesFrontiers in Medicine, 2020
Objective: The aim of our study was to assess the influence of the HLA-B27 status on axial spondyloarthritis (axSpA) in the largest cohort in China.Methods: An observational, cross-sectional, and analytic study of axSpA patients from the China axSpA ...
Shangzhu Zhang   +14 more
doaj   +1 more source

The Frequency of HLA-B27 Antigen Positivity in Patients with Rheumatoid Arthritis and Anklylosing Spondylitis and The Relationship Between HLA-B27 Antigen and Other Autoantibodies

open access: yesHitit Medical Journal
Objective: The aim of this study was to research the frequency of Human Leukocyte Antigen (HLA)-B27 antigen positivity and relationship between HLA-B27 positivity and other autoantibodies and between HLA-B27 positivity and ...
Gülseren Demir Karakılıç   +2 more
doaj   +1 more source

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