Results 11 to 20 of about 12,194 (179)

Mydriasis as a Secondary Effect in Patients With HLA‐B27–Associated Uveitis

Medicine Advances
Acute anterior uveitis (AAU) is the most common form of uveitis, and approximately 90% of AAU cases are associated with human leukocyte antigen (HLA)‐B27.
Saim Mahmood Khan, Menahil Faheem Siddiqui, Syeda Areesha Shoaib, Surraiya Riaz Mahmood Khan, Jawairya Muhammad Hussain, Syeda Faiqa Batool, Hudda Amjad   +6 more
doaj   +2 more sources

HLA B27 antigen in Middle Eastern and Arab countries: systematic review of the strength of association with axial spondyloarthritis and methodological gaps. [PDF]

BMC Musculoskelet Disord, 2017
Background Axial spondyloarthritis (AxSpA) is a relatively frequent and debilitating disease, with a prevalence ranging from 0.1 to 2% in the Caucasian population.
Ziade NR.
europepmc   +2 more sources

Does HLA-B27 Status Influence Ixekizumab Efficacy in Axial Spondyloarthritis? Results From the COAST-V, COAST-W, and COAST-X Trials. [PDF]

Rheumatol Ther
Introduction The human leukocyte antigen (HLA)-B27 is associated with axial spondyloarthritis (axSpA) and is a predictor of response to tumor necrosis factor inhibitors. However, limited data are available on HLA-B27 and interleukin-17 inhibitors.
Reveille JD, Rudwaleit M, Rahman P, Maldonado-Cocco JA, Magrey M, Bolce R, Ng KJ, Gibble TH, Lisse J, Park SY, Kronbergs A, Navarro-Compán V.   +11 more
europepmc   +2 more sources

Association of HLA-B27 antigen with clinical and laboratory parameters in patients with juvenile idiopathic arthritis [PDF]

Medicinski Glasnik, 2023
Aim To analyse the association of human leukocyte antigen B27 with clinical and laboratory parameters in patients with juvenile idiopathic arthritis (JIA) at the disease onset. Methods A retrospective review of medical records of 25 HLAB27 positive and
Adisa Čengić, Velma Selmanović, Sniježana Hasanbegović, Nedim Begić, Emina Karčić, Elma Fejzić   +5 more
doaj   +1 more source

The Art of Deception: Multiple Myeloma Imitating Spondyloarthritis-A Case Report. [PDF]

Clin Case Rep
ABSTRACT Rheumatic symptoms can be associated with malignancies. Although sacroiliitis is not a classic paraneoplastic syndrome, malignant infiltration of sacroiliac joints by multiple myeloma can mimic inflammatory rheumatologic disease. Multiple myeloma (MM), a plasma cell malignancy often presenting with bone pain, can involve axial skeletal ...
Khatri P, Subedi A, Dahal B, Shrestha G, Phuyal M, Adhikari R.   +5 more
europepmc   +2 more sources

Disease characteristics of HLA-B27 positive and negative finnish patients with juvenile idiopathic arthritis - results of the 18-year cohort follow-up study

Pediatric Rheumatology Online Journal, 2023
Background The aim of this long-term follow-up study was to compare the disease characteristics of HLA-B27 positive and negative patients with juvenile idiopathic arthritis (JIA).
Suvi Oili Orvokki Peltoniemi, Mia Glerup, Pekka Lahdenne, Kari K Eklund, Kristiina Aalto   +4 more
doaj   +1 more source

Intrinsic Folding Properties of the HLA-B27 Heavy Chain Revealed by Single Chain Trimer Versions of Peptide-Loaded Class I Major Histocompatibility Complex Molecules

Frontiers in Immunology, 2022
Peptide-loaded Major Histocompatibility Complex (pMHC) class I molecules can be expressed in a single chain trimeric (SCT) format, composed of a specific peptide fused to the light chain beta-2 microglobulin (β2m) and MHC class I heavy chain (HC) by ...
Izabela Lenart, Izabela Lenart, Izabela Lenart, Linh-Huyen Truong, Linh-Huyen Truong, Dinh Dung Nguyen, Dinh Dung Nguyen, Olga Rasiukienė, Edward Tsao, Jonathan Armstrong, Pankaj Kumar, Kirsty McHugh, Kirsty McHugh, Branca I. Pereira, Branca I. Pereira, Branca I. Pereira, Balraj S. Maan, Balraj S. Maan, Malgorzata A. Garstka, Paul Bowness, Neil Blake, Simon J. Powis, Keith Gould, Darren Nesbeth, Antony N. Antoniou, Antony N. Antoniou   +25 more
doaj   +1 more source

Clinical picture of ankylosing spondylitis in HLA-B27 positive and negative patients

Современная ревматология, 2023
The link between the HLA-B27 gene and ankylosing spondylitis (AS) has been known for almost 50 years. During this time, it has been discovered that some of the clinical manifestations of the disease are uniformly associated with the disease in almost all
Sh. F. Erdes, K. V. Sakharova
doaj   +1 more source

Targeted delivery of an antigenic peptide to the endoplasmic reticulum: application for development of a peptide therapy for ankylosing spondylitis. [PDF]

PLoS ONE, 2013
The development of suitable methods to deliver peptides specifically to the endoplasmic reticulum (ER) can provide some potential therapeutic applications of such peptides.
Hui-Chun Yu, Ming-Chi Lu, Chin Li, Hsien-Lu Huang, Kuang-Yung Huang, Su-Qin Liu, Ning-Sheng Lai, Hsien-Bin Huang   +7 more
doaj   +1 more source

Positivity and genotype distribution of HLA-B27 antigen in 7 829 patients with suspected ankylosing spondylitis

Di-san junyi daxue xuebao, 2020
Objective To analyze the positivity of human leukocyte surface antigen-B27 (HLA-B27) in patients with suspected ankylosing spondylitis (AS) and their relatives in Chongqing to understand the gender-specific distribution of HLA-B27 genotypes in the ...
GAO Lenyu, WU Hong, YOU Qingxia, WANG Yong   +3 more
doaj   +1 more source