Results 11 to 20 of about 93,215 (258)

The Frequency of HLA-B27 Antigen Positivity in Patients with Rheumatoid Arthritis and Anklylosing Spondylitis and The Relationship Between HLA-B27 Antigen and Other Autoantibodies

Hitit Medical Journal
Objective: The aim of this study was to research the frequency of Human Leukocyte Antigen (HLA)-B27 antigen positivity and relationship between HLA-B27 positivity and other autoantibodies and between HLA-B27 positivity and ...
Gülseren Demir Karakılıç, Esra Şahingöz Bakırcı, Ferda Büyük   +2 more
doaj   +4 more sources

HLA-B27 antigen in diagnosis of atypical seronegative inflammatory arthropathy. [PDF]

Annals of the Rheumatic Diseases, 1976
Eighteen patients with an inflammatory pauciarticular peripheral arthropathy not typical of any known entity showed an asymmetrical pattern of disease, with a predilection for the lower extremities. Destructive joint changes and deformities were absent (mean follow-up 10 years).
G. Joliat, A. Ferro, M. Jeannet, H. Ott
semanticscholar   +6 more sources

[Uveitis in spondyloarthritis patients and its association with HLA-B27 histocompatibility antigen: prospective study].

Vestnik oftal mologii, 2016
AIM to perform a prospective study of clinical presentation and course of uveitis in spondyloarthritis (SpA) patients as well as its association with the HLA-B27 histocompatibility antigen.
I. Razumova, A. Godzenko, O. K. Vorob'eva, I. A. Guseva   +3 more
semanticscholar   +2 more sources

Use of HLA-B27 tetramers to identify low-frequency antigen-specific T cells in Chlamydia-triggered reactive arthritis. [PDF]

, 2004
Reports of the use of HLA-B27/peptide tetrameric complexes to study peptide-specific CD8+ T cells in HLA-B27+-related diseases are rare. To establish HLA-B27 tetramers we first compared the function of HLA-B27 tetramers with HLA-A2 tetramers by using ...
Appel, H, Bowness, Paul, Kollnberger, Simon, Kuhlmann, S, Kuhne, M, Kuon, W, Sieper, J, Thiel, A, Wu, P   +8 more
core   +5 more sources

Granulocyte-macrophage colony-stimulating factor may contribute to spondyloarthritis development in HLA-B27 transgenic rat by affecting conventional dendritic cells function [PDF]

Arthritis Research & Therapy
Background Spondyloarthritis (SpA) is a chronic inflammatory disorder with axial and peripheral manifestations. A strong association between HLA-B27 and SpA has been known for more than 50 years.
Amel Ait Ali Said, Chiara Rizzo, Hendrick Mambu Mambueni, Félicie Costantino, Maxime Breban, Simon Glatigny   +5 more
doaj   +2 more sources

The rapid detection of human HLA-B*27 gene based on BASIC isothermal detection [PDF]

Scientific Reports
Ankylosing spondylitis (AS) is a chronic, inflammatory arthritis of the spine and peripheral joints which is known to have a strong association with the human leukocyte antigen B27 (HLA-B27).
Ying Chen, Jianing Ren, Xin Yang, Zhanggang Li, Wenwen Wu, Guangcheng Luo, Yuan Xu, Hongjun Yang, Qiang Wang, Qing Zhang   +9 more
doaj   +2 more sources

Genetic modulation of antigen presentation by HLA-B27 molecules. [PDF]

The Journal of experimental medicine, 1992
In studies of antigenic peptide presentation, we have found a healthy volunteer whose lymphoblastoid cells were unable to present three different virus-derived epitopes to cytotoxic T lymphocytes (CTL) despite expressing the correct restricting HLA-B27 molecules on the cell surface. B cell lines were established from other members of the donor's family,
L Pazmany, Sarah Rowland‐Jones, Stéphane Huet, Ann B. Hill, John Sutton, Rachael Z. Murray, Jill Brooks, Andrew J. McMichael   +7 more
openalex   +5 more sources

Autoinflammation and HLA-B27: Beyond Antigen Presentation [PDF]

Ocular Immunology and Inflammation, 2016
HLA-B27 associated disorders comprise a group of inflammatory conditions which have in common an association with the HLA class I molecule, HLA-B27. Given this association, these diseases are classically considered disorders of adaptive immunity. However, mounting data are challenging this assumption and confirming that innate immunity plays a more ...
C. Sibley
semanticscholar   +4 more sources

Features of the course of anterior uveitis associated with HLA-B27 antigen

Vestnik oftal'mologii, 2019
To perform comparative analysis of the frequency of various complications of anterior uveitis associated with HLA-B27 antigen in patients with and without spondyloarthritis.Retrospective analysis included 189 patients with anterior uveitis (AU) associated with histocompatibility antigen (HLA-B27).
I. Yu. Razumova, А. А. Годзенко, И. А. Гусева   +2 more
openalex   +4 more sources

Delineation of functional sites in HLA-B27 antigens. Molecular analysis of HLA-B27 variant Wewak I defined by cytolytic T lymphocytes. [PDF]

The Journal of Immunology, 1985
Abstract An HLA-B27 positive, Epstein Barr virus-transformed cell line Wewak I was not lysed by Epstein Barr virus-specific cytolytic T lymphocytes restricted by HLA-B27. This line is weakly reactive with a B27-specific monoclonal antibody, M2, which recognizes a majority, but not all, of the HLA-B27-positive cells.
Miguel A. Vega, Lesley E. Wallace, Susana Rojo‐Alba, Rafael Bragado, Pedro Aparício, José A. Łópez de Castro   +5 more
openalex   +3 more sources