Results 21 to 30 of about 164,764 (309)
The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies. [PDF]
Central to the humoral theory of transplantation is production of antibodies by the recipient against mismatched HLA antigens in the donor organ. Not all mismatches result in antibody production, however, and not all antibodies are pathogenic.
Farber, John, Filippone, Edward J
core +8 more sources
Immunity to infections with Measles Virus (MV) can involve vigorous HLA class I restricted CD8+ cytotoxic T cell (CTL) responses. MV, albeit regarded monotypic, is known to undergo molecular evolution across its RNA genome.
Ingrid eSchellens +17 more
doaj +1 more source
Polymorphism of leukocyte and erythrocyte antigens in chronic kidney disease patients in southern Brazil. [PDF]
We investigated the polymorphism of human leukocyte antigens (HLA) and Duffy erythrocyte antigens in chronic kidney disease (CKD) patients in southern Brazil.
Roger Haruki Yamakawa +4 more
doaj +1 more source
Immunodominant Tuberculosis CD8 Antigens Preferentially Restricted by HLA-B
CD8(+) T cells are essential for host defense to intracellular bacterial pathogens such as Mycobacterium tuberculosis (Mtb), Salmonella species, and Listeria monocytogenes, yet the repertoire and dominance pattern of human CD8 antigens for these pathogens remains poorly characterized.
Deborah A Lewinsohn +9 more
openaire +4 more sources
Host genetics and viral load in primary HIV-1 infection: clear evidence for gene by sex interactions [PDF]
© 2014, The Author(s).Research in the past two decades has generated unequivocal evidence that host genetic variations substantially account for the heterogeneous outcomes following human immunodeficiency virus type 1 (HIV-1) infection.
Allen, S +14 more
core +1 more source
Studies devoted to the role of human leucocyte antigens (HLA) in pathogenesis of chronic kidney disease (CKD) have demonstrated the associative links of the HLA antigens, which stipulate the relative and attributive risks of some autoimmune diseases ...
V. Driianska +4 more
doaj +1 more source
BACKGROUND: As being the first bacteria determined to be carcinogenic, Helicobacter pylori (H. pylori) is a pathogen localized in the stomach in more than half of the world population.
Sevim GÖNEN +4 more
doaj +1 more source
Antibodies (a/t) to antigens (a/g) of human tissue compatibility HLA (human leucocyte antigens) are the main cause of kidney transplant rejection. Antigens of the HLAI class system (loci A, B, C) are present on all nucleated cells of the body, HLA class
Елена Борисовна Лукоянычева +7 more
doaj
Human Leukocyte Antigen - HLA B*27: Unraveling the Link to Pathogenesis
The association of spondyloarthritis (SpA) with human leukocyte antigen-B*27 (HLA-B*27) is one of the strongest known for a non-monogenic disease. How HLA-B*27 determines the aetiopathogenesis of SpA and disposes toward this group of disease has perplexed rheumatologists for decades.
Sakir Ahmed, Ramnath Misra
openaire +2 more sources
HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles [PDF]
AbstractExtracellular vesicles can modulate diverse processes ranging from proliferation and tissue repair, to chemo-resistance and cellular differentiation. With the advent of tissue and immunological targeting, extracellular vesicles are also increasingly viewed as promising vectors to deliver peptide-based cancer antigens to the human immune system.
Julia Bauzá-Martinez +2 more
openaire +4 more sources

