Results 21 to 30 of about 164,764 (309)

The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies. [PDF]

open access: yes, 2016
Central to the humoral theory of transplantation is production of antibodies by the recipient against mismatched HLA antigens in the donor organ. Not all mismatches result in antibody production, however, and not all antibodies are pathogenic.
Farber, John, Filippone, Edward J
core   +8 more sources

Measles virus epitope presentation by HLA: novel insights into epitope selection, dominance and microvariation

open access: yesFrontiers in Immunology, 2015
Immunity to infections with Measles Virus (MV) can involve vigorous HLA class I restricted CD8+ cytotoxic T cell (CTL) responses. MV, albeit regarded monotypic, is known to undergo molecular evolution across its RNA genome.
Ingrid eSchellens   +17 more
doaj   +1 more source

Polymorphism of leukocyte and erythrocyte antigens in chronic kidney disease patients in southern Brazil. [PDF]

open access: yesPLoS ONE, 2014
We investigated the polymorphism of human leukocyte antigens (HLA) and Duffy erythrocyte antigens in chronic kidney disease (CKD) patients in southern Brazil.
Roger Haruki Yamakawa   +4 more
doaj   +1 more source

Immunodominant Tuberculosis CD8 Antigens Preferentially Restricted by HLA-B

open access: yesPLoS Pathogens, 2007
CD8(+) T cells are essential for host defense to intracellular bacterial pathogens such as Mycobacterium tuberculosis (Mtb), Salmonella species, and Listeria monocytogenes, yet the repertoire and dominance pattern of human CD8 antigens for these pathogens remains poorly characterized.
Deborah A Lewinsohn   +9 more
openaire   +4 more sources

Host genetics and viral load in primary HIV-1 infection: clear evidence for gene by sex interactions [PDF]

open access: yes, 2014
© 2014, The Author(s).Research in the past two decades has generated unequivocal evidence that host genetic variations substantially account for the heterogeneous outcomes following human immunodeficiency virus type 1 (HIV-1) infection.
Allen, S   +14 more
core   +1 more source

Peculiarities of phenotypes of patients with pyelo- and glomerulonephritis by HLA distribution analysis

open access: yesУкраїнський Журнал Нефрології та Діалізу, 2018
Studies devoted to the role of human leucocyte antigens (HLA) in pathogenesis of chronic kidney disease (CKD) have demonstrated the associative links of the HLA antigens, which stipulate the relative and attributive risks of some autoimmune diseases ...
V. Driianska   +4 more
doaj   +1 more source

EVALUATION OF HUMAN LEUKOCYTE ANTIGEN CLASS I AND II ANTIGENS IN HELICOBACTER PYLORI-POSITIVE PEDIATRIC PATIENTS WITH ACTIVE GASTRITIS AND DUODENAL ULCER

open access: yesArquivos de Gastroenterologia, 2017
BACKGROUND: As being the first bacteria determined to be carcinogenic, Helicobacter pylori (H. pylori) is a pathogen localized in the stomach in more than half of the world population.
Sevim GÖNEN   +4 more
doaj   +1 more source

FREQUENCY OF OCCURRENCE OF ANTIBODIES TO HLA ANTIGENS IN RECIPIENTS ON THE WAITING LIST FOR KIDNEY TRANSPLANTATION

open access: yesМедицина в Кузбассе, 2023
Antibodies (a/t) to antigens (a/g) of human tissue compatibility HLA (human leucocyte antigens) are the main cause of kidney transplant rejection. Antigens of the HLAI class system (loci A, B, C) are present on all nucleated cells of the body, HLA class
Елена Борисовна Лукоянычева   +7 more
doaj  

Human Leukocyte Antigen - HLA B*27: Unraveling the Link to Pathogenesis

open access: yesIndian Journal of Rheumatology, 2020
The association of spondyloarthritis (SpA) with human leukocyte antigen-B*27 (HLA-B*27) is one of the strongest known for a non-monogenic disease. How HLA-B*27 determines the aetiopathogenesis of SpA and disposes toward this group of disease has perplexed rheumatologists for decades.
Sakir Ahmed, Ramnath Misra
openaire   +2 more sources

HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles [PDF]

open access: yesCommunications Biology, 2021
AbstractExtracellular vesicles can modulate diverse processes ranging from proliferation and tissue repair, to chemo-resistance and cellular differentiation. With the advent of tissue and immunological targeting, extracellular vesicles are also increasingly viewed as promising vectors to deliver peptide-based cancer antigens to the human immune system.
Julia Bauzá-Martinez   +2 more
openaire   +4 more sources

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