Results 171 to 180 of about 375,043 (313)

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Human Leukocyte Antigen (HLA) and Tumor Immunity: A Critical Link in Cancer Immunotherapy. [PDF]

Immun Inflamm Dis
Damian D.
europepmc   +1 more source

ASSOCIATION OF HLA COMPATIBILITY AND DECREASED LIVER-TRANSPLANT SURVIVAL [PDF]

, 1988
BRYAN, C, DUQUESNOY, RJ, FUNG, JJ, GORDON, RD, KLINTMALM, G, MARKUS, BH, STARZL, TE, VANEK, M, VANTHIEL, D   +8 more
core  

A Tripartite Model for EBV‐Driven Multiple Sclerosis: B Cell Survival, Altered Self‐Presentation, and HLA‐DR15‐Restricted T Cell Cross‐Reactivity

iNew Medicine, EarlyView.
ABSTRACT This commentary integrates findings from three recent Cell reports to establish a unified mechanistic model of multiple sclerosis (MS) driven by the interplay between Epstein‐Barr virus (EBV) and the HLA‐DR15 genotype. EBV promotes CNS autoimmunity through three distinct but intersecting mechanisms.
Fang Zhu, Arnaud John Kombe Kombe, Tengchuan Jin   +2 more
wiley   +1 more source

Population HLA coverage of experimentally characterized <i>P. falciparum CD8</i> ^<i>+</i> T cell epitopes as potential components of a multi-epitope malaria vaccine construct: an <i>in silico</i> insight. [PDF]

Front Bioinform
Siame C, Abdul-Mumin R, Agyekum G, Akuffo L, Afari E, Yankey CAB, Kusi KA.   +6 more
europepmc   +1 more source

Monocytes with trained immunity–like signatures are associated with acute anterior uveitis in ankylosing spondylitis

Interdisciplinary Medicine, EarlyView.
In ankylosing spondylitis‐acute anterior uveitis (AS‐AAU), trained immunity monocytes (Mono‐TI) differentiate into macrophages in the eye, retaining trained immunity features. Mono‐TI cells secrete pro‐inflammatory cytokines and chemokines, including IL‐1β, TNF‐α, and CCL3.
Yimeng Sun, Lu Zhang, Xinyu Yao, Yunfei Liu, Xin Li, Feng Wen, Yong Dai, Ye Dai, Ziyu Du, Dijie Qiao, Ziwei Meng, Cong Hu, Chun Yan, Wei Chi   +13 more
wiley   +1 more source

Tumor-infiltrating T Lymphocytes Recognize Thyroid-specific Proteins and Neo-antigens in Follicular Cell-derived Thyroid Cancers.

J Clin Endocrinol Metab
Garza B, Calhoun J, Norman PJ, Cline N, Kichula KM, Farias TDJ, Sams S, Boorgula MP, Danhorn T, Haugen BR, French JD.   +10 more
europepmc   +1 more source

Effective allogeneic natural killer cell therapy for pancreatic adenocarcinoma avails conserved activating receptors and evades HLA I-driven inhibition. [PDF]

J Immunother Cancer
Lee SN, Arseneau RJ, Arnason T, Boudreau JE.   +3 more
europepmc   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source

Mechanistic Insights from Human Studies in Axial Spondyloarthritis: A T Cell Story. [PDF]

Curr Rheumatol Rep
Um J, Paley MA.
europepmc   +1 more source