Results 181 to 190 of about 30,072 (217)

Evidence for Two Series of B‐Cell Antigens in Man and Their Comparison with HLA‐D

Scandinavian Journal of Immunology, 1977
Population mid family studies of five sera with antibodies against B‐cell determinants show an excellent fit of some of them with the HLA‐D determinants, suggesting that the HLA‐D determinants themselves or closely linked structures can be recognized by serology.
J J, van Rood, A, van Leeuwen, J J, Keuning, A, Termijtelen   +3 more
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HLA-D Related Antigens in Inflammatory Bowel Disease

1981
There is good evidence that genetic as well as environmental factors are important in the aetiology of inflammatory bowel disease (1). However, studies of HLA-A and -B specificities have not shown consistent differences between patients and controls. Nevertheless an investigation of the HLA-D related [DR] antigens in such patients would be of interest ...
W. R. Burnham, K. Gelsthorpe, M. J. S. Langman   +2 more
openaire   +1 more source

Importance of HLA‐D antigens for the cooperation between human monocytes and T lymphocytes

European Journal of Immunology, 1978
AbstractThe ability of autologous and allogeneic monocytes to restore the responsiveness of purified T lymphocytes to tuberculin (PPD) was studied in twelve different experiments involving eleven unrelated T lymphocyte donors and a large number of related and unrelated monocyte donors.
G S, Hansen, B, Rubin, S F, Sørensen, A, Svejgaard   +3 more
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Primed LD Typing: Reagent Preparation and Definition of the HLA‐D‐Region Antigens

Scandinavian Journal of Immunology, 1977
Primed LD typing cells were prepared against single HLA haplotypes within families and used to type a random panel of 48 individuals. PLT cells could be grouped on the basis of highly correlated responses with the panel test cells; the 21 different PLT cells could be used to define 6 different PL antigens. One of these, PL 3, was split by the responses
F H, Bach, E K, Jarrett-Toh, C J, Benike, C Y, Shih, E A, Valentine, P M, Sondel, M L, Bach   +6 more
openaire   +2 more sources

HLA-DB3: population distribution and family studies of a new HLA-D antigen associated with HLA-D antigen associated with HLA-DR4 in Caucasoids.

Tissue antigens, 1983
On the basis of studies with 6 HTCs in four different families the new cluster DB3 identified in the 8th Workshop can be considered an established specificity of the HLA-D series. In 112 healthy Caucasoids resident in South East England the frequency of this antigen was 2.6% similar to the frequency found in 142 Caucasoid patients with rheumatoid ...
Jaraquemada, D, Ollier, William, Okoye, R, Sachs, J, Festenstein, H, Grosse-wilde, H   +5 more
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HLA‐D/DR Restriction of Macrophage‐dependent Antigen Activation of Immune T Lymphocytes: Cross‐reacting Allogeneic HLA‐D/DR May Partly Substitute for Self HLA‐D/DR

Scandinavian Journal of Immunology, 1980
Optimal proliferative response of T lymphocytes to purified protein derivative of tuberculin (PPD) III vitro requires that antigen be presented by autologous macrophages or allogeneic macrophages sharing HLA‐D/DR determinants with the T cell donor. In some cases, however, T cells may respond to a limited extent to PPD in association with macrophages ...
B O, Bergholtz, A B, Thoresen, E, Thorsby   +2 more
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HLA-D and -DR antigens on human amniotic fluid cells. I. Lack of expression of HLA-D.

Tissue antigens, 1983
Human amniotic fluid cells, known to express HLA-A, -B, and -C antigens, were tested for the presence of lymphocyte-stimulating antigens (LD or HLA-D) using modifications of the mixed lymphocyte culture (MLC) and primed lymphocyte typing (PLT) tests. Peripheral blood lymphocytes were co-cultured with various concentrations of allogeneic amniotic fluid ...
E, Valentine-Thon, G, Kreeb, H, Grosse-Wilde, E, Passarge   +3 more
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HLA‐D restriction of antigen‐specific proliferative T cell responses

Tissue Antigens, 1983
The specificity of the inhibitory activity of anti HLA‐DR antisera on the proliferative response of human T cells to soluble antigens has been recently challenged. Furthermore, there are conflicting reports about the effect of antisera to the stimulatory antigen.
E. Thorsby, S. Ferrone, H. Nousiainen, H. Hirschberg   +3 more
openaire   +1 more source

HLA‐D/DR restriction of proliferative T cell responses to antigen

Tissue Antigens, 1982
Antigen‐specific T cell blasts may be separated from alloreactive cells on Percoll gradients. The absence of alloreactivity allowed us to study HLA‐D/DR restriction of proliferative T cell responses towards PPD and HSV antigens using allogeneic antigen‐presenting cells.
E. J. Berle, A. B. Thoresen, E. Thorsby
openaire   +1 more source

Biochemical analysis of the polymorphism of three HLA-D region antigens.

Molecular biology & medicine, 1984
Two-dimensional gel electrophoretic analyses of immunoprecipitates of the HLA-D region antigens revealed three beta (Mr 28 X 10(3) to 30 X 10(3) structurally polymorphic polypeptides. Analyses of the nonglycosylated beta polypeptides indicated that their polymorphism is most probably due to variations in amino acid structure.
T, de Kretser, M J, Crumpton, J G, Bodmer, W F, Bodmer   +3 more
openaire   +1 more source