Results 21 to 30 of about 125,944 (285)

Expression of HLA-DR in pheripheral nerve of amyotrophic lateral sclerosis

Arquivos de Neuro-Psiquiatria, 1994
To investigate the possibility of local antigen presentation within the peripheral nerve in amyotrophic lateral sclerosis (ALS), cryostat sections of 83 peripheral nerve biopsies were stained for the demonstration of HLA-DR using a monoclonal antibody ...
A.S.B. Oliveira, E. Isozaki, D. Younger, A.A. Gabbai, A.P. Hays   +4 more
doaj   +1 more source

The effect of interleukin-10 and transforming growth factor β-1 on HLA-DR expression in colonic epithelial cells

Mediators of Inflammation, 1998
The aim of this study was to assess whether interleukin-10 (IL-10) and/or transforming growth factor β-1 (TGF β1) downregulate HLA-DR expression using the HT29 cell line as a model of colonic epithelial cells.
M. J. Zimmerman, G. R. Radford-Smith, D. P. Jewell   +2 more
doaj   +1 more source

Generation of functional HLA-DR*1101 tetramers receptive for loading with pathogen or tumour derived synthetic peptides

BMC Immunology, 2005
Background MHC class I-peptide tetramers are currently utilised to characterize CD8+ T cell responses at single cell level. The generation and use of MHC class II tetramers to study antigen-specific CD4+ T cells appears less straightforward.
Protti Maria, Glaichenhaus Nicholas, Giabbai Barbara, Degano Massimo, Dallegno Eliana, Martinoli Chiara, Cecconi Virginia, Moro Monica, Dellabona Paolo, Casorati Giulia   +9 more
doaj   +1 more source

Increased expressions of CD123, CD63, CD203c, and Fc epsilon receptor I on blood leukocytes of allergic asthma

Frontiers in Molecular Biosciences, 2022
Background: Altered basophil identification markers have been discovered to associate with allergic asthma (AA) in recent years. However, little is known about the expression of basophil markers in blood granulocytes.Aim: To parallel test blood basophils
Hua Xie, Hua Xie, Liping Chen, Liping Chen, Huiyun Zhang, Junling Wang, Yanyan Zang, Mengmeng Zhan, Fangqiu Gu, Shunlan Wang, Shaoheng He, Shaoheng He   +11 more
doaj   +1 more source

Matching for HLA-DR excluding diabetogenic HLA-DR3 and HLA-DR4 predicts insulin independence after pancreatic islet transplantation

Frontiers in Immunology, 2023
IntroductionIn pancreatic islet transplantation, the exact contribution of human leukocyte antigen (HLA) matching to graft survival remains unclear. Islets may be exposed to allogenic rejection but also the recurrence of type 1 diabetes (T1D).
Cassandra Ballou, Franca Barton, Elizabeth H. Payne, Thierry Berney, Jean Villard, Raphael P. H. Meier, David Baidal, Rodolfo Alejandro, Mark Robien, Thomas L. Eggerman, Malek Kamoun, Yannick D. Muller   +11 more
doaj   +1 more source

Correlation Study on HLA-DR and CD117 (c-Kit) Expressions: Its Prognosis and Treatment Response in Acute Myeloid Leukemia Patients

Pharmacogenomics and Personalized Medicine, 2021
Yomna M El-Meligui,1 Heba E Abd Elrhman,2 Ahmad Salahuddin,3 Manal Ali Hamouda,4 Amira B Kassem5 1Department of Clinical Pathology, National Cancer Institute, Cairo University, Cairo, Egypt; 2Department of Clinical Pathology, Faculty of Medicine, Zagazig
El-Meligui YM, Abd Elrhman HE, Salahuddin A, Hamouda MA, Kassem AB   +4 more
doaj  

Decreased Monocyte HLA-DR Expression in Patients with Sepsis and Acute Kidney Injury

Medicina, 2022
Background and objectives: Acute kidney injury (AKI) is common in critically ill patients, especially those with sepsis. Persistently low human leukocyte antigen (HLA)-DR expression in monocytes reflects the decreased function of antigen-presenting cells,
Huang-Pin Wu, Li-Pang Chuang, Pi-Hua Liu, Chien-Ming Chu, Chung-Chieh Yu, Shih-Wei Lin, Kuo-Chin Kao, Li-Fu Li, Duen-Yau Chuang   +8 more
doaj   +1 more source

Dynamic changes of the proportion of HLA-DR and CD38 coexpression subsets on T lymphocytes during IFN-based chronic hepatitis B treatment

Frontiers in Immunology, 2023
BackgroundTo investigate the changes of human leukocyte antigen DR (HLA-DR) and CD38 coexpression subsets on T lymphocytes following interferon (IFN) therapy for those who have chronic hepatitis B (CHB).MethodsA prospective cohort of CHB patients ...
Yanjie Lin, Ge Shen, Si Xie, Xiaoyue Bi, Huihui Lu, Liu Yang, Tingting Jiang, Wen Deng, Shiyu Wang, Lu Zhang, Yao Lu, Yuanjiao Gao, Hongxiao Hao, Shuling Wu, Ruyu Liu, Min Chang, Mengjiao Xu, Leiping Hu, Xiaoxue Chen, Ronghai Huang, Minghui Li, Minghui Li, Yao Xie, Yao Xie   +23 more
doaj   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source