Results 31 to 40 of about 1,839,216 (336)

Probiotics Reduce Inflammation in Antiretroviral Treated, HIV-Infected Individuals: Results of the "Probio-HIV" Clinical Trial [PDF]

, 2015
BACKGROUND: HIV infection results in damage to the gastrointestinal (GI) tract, microbial translocation and immune activation. These are not completely normalized with combined antiretroviral therapy (cART).
ASCOLI BARTOLI, Tommaso, Bellelli, Valeria, Bianchi, Luigi, Brenchley, Jason M, Calantone, Nina, Ceccarelli, Giancarlo, D'Ettorre, Gabriella, De Girolamo, Gabriella, Giustini, Noemi, Marcellini, Sonia, Serafino, Sara, Turriziani, Ombretta, Vullo, Vincenzo   +12 more
core   +7 more sources

Expression of HLA-DR genes in gliomas: correlation with clinicopathological features and prognosis

Chinese Neurosurgical Journal, 2017
Background Human leukocyte antigen (HLA)-DR is a classical major histocompatibility complex (MHC) class II molecule encoded by five genes: HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4 and HLA-DRB5.
Xing Fan, Jingshan Liang, Zhifeng Wu, Xia Shan, Hui Qiao, Tao Jiang   +5 more
doaj   +1 more source

HLA-DR-Positive NK Cells Expand in Response to Mycobacterium Tuberculosis Antigens and Mediate Mycobacteria-Induced T Cell Activation

Frontiers in Immunology, 2021
NK cells play an important role in the control of tuberculosis infection: they are not only able to kill the infected cells, but also control the activity of macrophages and development of the adaptive immune response.
Sofya A. Kust, Maria A. Streltsova, Alexander V. Panteleev, Natalya L. Karpina, Irina V. Lyadova, Irina V. Lyadova, Alexander M. Sapozhnikov, Elena I. Kovalenko   +7 more
doaj   +1 more source

The influence of HLA matching on cytomegalovirus hepatitis and chronic rejection after liver transplantation [PDF]

, 1993
Previous findings in liver transplantation patients have raised the concept that HLA plays a dualistic role. HLA matching will reduce rejection but may augment MHC restricted cellular immune mechanisms of liver allograft injury. To evaluate this concept,
Demetris, AJ, Duquesnoy, RJ, Kramer, D, Kusne, S, Linden, P, Martin, M, Mañez, R, Starzl, TE, Van Thiel, DH, White, LT   +9 more
core   +1 more source

HLA‐DR/DQ molecular mismatch: A prognostic biomarker for primary alloimmunity

American Journal of Transplantation, 2018
Alloimmune risk stratification in renal transplantation has lacked the necessary prognostic biomarkers to personalize recipient care or optimize clinical trials.
C. Wiebe, V. Kosmoliaptsis, Denise Pochinco, I. Gibson, J. Ho, P. Birk, A. Goldberg, M. Karpinski, Jamie Shaw, D. Rush, P. Nickerson   +10 more
semanticscholar   +1 more source

Epidemiology and immunogenetic background of islet cell antibody - positive nondiabetic schoolchildren : Ulm-Frankfurt population study [PDF]

, 1991
Islet cell antibodies (ICAs) were determined in a large cohort of white nondiabetic schoolchildren (n = 4287) from a homogenous population in southern Germany.
Böhm, Bernhard Otto, Glück, Michael, Holzberger, G., Kühnl, Peter, Manfras, Burkhard J., Scherbaum, Werner A., Schöffling, Karl, Seidl, S., Seißler, Jochen, Trucco, Massimo   +9 more
core   +1 more source

Quantitative Spatial Profiling of PD-1/PD-L1 Interaction and HLA-DR/IDO-1 Predicts Improved Outcomes of Anti–PD-1 Therapies in Metastatic Melanoma

Clinical Cancer Research, 2018
Purpose: PD-1/L1 axis–directed therapies produce clinical responses in a subset of patients; therefore, biomarkers of response are needed. We hypothesized that quantifying key immunosuppression mechanisms within the tumor microenvironment by ...
Douglas B. Johnson, J. Bordeaux, J. Kim, C. Vaupel, D. Rimm, T. Ho, R. Joseph, A. Daud, R. Conry, Elizabeth M. Gaughan, L. Hernandez-Aya, A. Dimou, P. Funchain, J. Smithy, J. Witte, Svetlana B. McKee, J. Ko, J. Wrangle, B. Dabbas, S. Tangri, J. Lameh, Jeff M. Hall, J. Markowitz, J. Balko, N. Dakappagari   +24 more
semanticscholar   +1 more source

The effect of interleukin-10 and transforming growth factor β-1 on HLA-DR expression in colonic epithelial cells

Mediators of Inflammation, 1998
The aim of this study was to assess whether interleukin-10 (IL-10) and/or transforming growth factor β-1 (TGF β1) downregulate HLA-DR expression using the HT29 cell line as a model of colonic epithelial cells.
M. J. Zimmerman, G. R. Radford-Smith, D. P. Jewell   +2 more
doaj   +1 more source

Generation of functional HLA-DR*1101 tetramers receptive for loading with pathogen or tumour derived synthetic peptides

BMC Immunology, 2005
Background MHC class I-peptide tetramers are currently utilised to characterize CD8+ T cell responses at single cell level. The generation and use of MHC class II tetramers to study antigen-specific CD4+ T cells appears less straightforward.
Protti Maria, Glaichenhaus Nicholas, Giabbai Barbara, Degano Massimo, Dallegno Eliana, Martinoli Chiara, Cecconi Virginia, Moro Monica, Dellabona Paolo, Casorati Giulia   +9 more
doaj   +1 more source

Immunological Compatibility Status of Placenta-Derived Stem Cells is Mediated by Scaffold 3D Structure [PDF]

, 2018
Placenta-derived amniotic epithelial cells (AECs), a great cell source for tissue engineering and stem cell therapy, are immunologically inert in their native state; however, immunological changes in these cells after culture and differentiation have ...
Azizian, Sara, Bahrami, Soheyl, Katami, Fatemeh, Modaresifar, Khashayar, Mosaffa, Nariman, Niknejad, Hassan, Peirovi, Habibollah, Redl, Heinz, Tayebi, Lobat   +8 more
core   +2 more sources