Results 51 to 60 of about 1,839,216 (336)

Correlation Study on HLA-DR and CD117 (c-Kit) Expressions: Its Prognosis and Treatment Response in Acute Myeloid Leukemia Patients

Pharmacogenomics and Personalized Medicine, 2021
Yomna M El-Meligui,1 Heba E Abd Elrhman,2 Ahmad Salahuddin,3 Manal Ali Hamouda,4 Amira B Kassem5 1Department of Clinical Pathology, National Cancer Institute, Cairo University, Cairo, Egypt; 2Department of Clinical Pathology, Faculty of Medicine, Zagazig
El-Meligui YM, Abd Elrhman HE, Salahuddin A, Hamouda MA, Kassem AB   +4 more
doaj  

Adipose-derived mesenchymal stem cells from patients with atherosclerotic renovascular disease have increased DNA damage and reduced angiogenesis that can be modified by hypoxia [PDF]

, 2016
Representative flow cytometric plots (FACS) showing that AMSCs expressed HLA-ABC, CD44, CD90, CD29, CD73, and CD105 markers, and did not express HLA-DR, CD45, CD14 or CD34 markers.
Ahmed Saad, Allan B. Dietz, Andre J. van Wijnen, Hui Tang, LaTonya Hickson, Lilach Lerman, Sandra Herrmann, Stephen Textor, Xiang-Yang Zhu   +8 more
core   +3 more sources

Decreased Monocyte HLA-DR Expression in Patients with Sepsis and Acute Kidney Injury

Medicina, 2022
Background and objectives: Acute kidney injury (AKI) is common in critically ill patients, especially those with sepsis. Persistently low human leukocyte antigen (HLA)-DR expression in monocytes reflects the decreased function of antigen-presenting cells,
Huang-Pin Wu, Li-Pang Chuang, Pi-Hua Liu, Chien-Ming Chu, Chung-Chieh Yu, Shih-Wei Lin, Kuo-Chin Kao, Li-Fu Li, Duen-Yau Chuang   +8 more
doaj   +1 more source

Dynamic changes of the proportion of HLA-DR and CD38 coexpression subsets on T lymphocytes during IFN-based chronic hepatitis B treatment

Frontiers in Immunology, 2023
BackgroundTo investigate the changes of human leukocyte antigen DR (HLA-DR) and CD38 coexpression subsets on T lymphocytes following interferon (IFN) therapy for those who have chronic hepatitis B (CHB).MethodsA prospective cohort of CHB patients ...
Yanjie Lin, Ge Shen, Si Xie, Xiaoyue Bi, Huihui Lu, Liu Yang, Tingting Jiang, Wen Deng, Shiyu Wang, Lu Zhang, Yao Lu, Yuanjiao Gao, Hongxiao Hao, Shuling Wu, Ruyu Liu, Min Chang, Mengjiao Xu, Leiping Hu, Xiaoxue Chen, Ronghai Huang, Minghui Li, Minghui Li, Yao Xie, Yao Xie   +23 more
doaj   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Serial Increases in Human Leukocyte Antigen-DR Expression and Decreases in Interleukin-10 Expression in Alveolar Monocytes of Survivors of Pneumonia-Related Acute Respiratory Distress Syndrome

Biology, 2022
ARDS is a potentially lethal syndrome. HLA-DR expression in monocytes reflects their activation and antigen-presenting capacity. However, the correlation between clinical outcomes and HLA-DR expression in alveolar monocytes/macrophages in patients with ...
Chien-Ming Chu, Chia-Jung Chung, Chih-Yu Huang, Chung-Chieh Yu, Chao-Hung Wang, Li-Fu Li, Huang-Pin Wu   +6 more
doaj   +1 more source

SPARC is a new myeloid-derived suppressor cell marker licensing suppressive activities [PDF]

, 2019
Myeloid-derived suppressor cells (MDSC) are well-known key negative regulators of the immune response during tumor growth, however scattered is the knowledge of their capacity to influence and adapt to the different tumor microenvironments and of the ...
Botti L., Cappetti B., Chiodoni C., Colombo M. P., Consonni F. M., Gulino A., Nicola M. D., Portararo P., Randon G., Sangaletti S., Sica A., Talarico G., Tripodo C.   +12 more
core   +3 more sources

Sampling From the Proteome to the Human Leukocyte Antigen-DR (HLA-DR) Ligandome Proceeds Via High Specificity*

Molecular & Cellular Proteomics, 2016
Comprehensive analysis of the complex nature of the Human Leukocyte Antigen (HLA) class II ligandome is of utmost importance to understand the basis for CD4+ T cell mediated immunity and tolerance.
Geert P. M. Mommen, F. Marino, H. Meiring, M. Poelen, J. A. M. van Gaans-van den Brink, S. Mohammed, A. Heck, C. V. van Els   +7 more
semanticscholar   +1 more source

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink, Austin Wheeler, Bryant R. England, Solbritt Rantapää‐Dahlqvist   +3 more
wiley   +1 more source

The causal relationship between immune cells and diabetic retinopathy: a Mendelian randomization study

Frontiers in Immunology
PurposeThis article explored the causal relationship between immune cells and diabetic retinopathy (DR) using single nucleotide polymorphisms (SNPs) as an instrumental variable and Mendelian randomization (MR).MethodsStatistical data were collected from ...
Yunyan Ye, Lei Dai, Hong Gu, Lan Yang, Zhangxing Xu, Zhiguo Li   +5 more
doaj   +1 more source