Results 1 to 10 of about 114,761 (352)
Quantitative Predictions of Peptide Binding to Any HLA-DR Molecule of Known Sequence: NetMHCIIpan [PDF]
PLoS Computational Biology, 2008 CD4 positive T helper cells control many aspects of specific immunity. These cells are specific for peptides derived from protein antigens and presented by molecules of the extremely polymorphic major histocompatibility complex (MHC) class II system. The
Morten Nielsen +2 more
exaly +8 more sources
Prediction of immunogenicity of Rh antigens using in silico analysis of binding to human leukocyte antigen peptide, Basic/Translational Research. [PDF]
PLoS ONEThe association between human leukocyte antigen (HLA) types and blood group alloimmunization remains unclear. Previous studies have predominantly focused on predicting immunization events in cancer immunotherapy, but not blood group antigens.
Hee-Jeong Youk +4 more
doaj +2 more sources
Challenges of monocyte HLA-DR targeted immunomodulation in sepsis—a prospective observational cohort study [PDF]
Frontiers in ImmunologyIntroductionReduced monocyte HLA-DR expression, a hallmark of immunosuppression in sepsis, is associated with infectious complications and mortality. Therapeutic strategies, including IFN-γ, have been used to restore monocyte HLA-DR and immune function ...
Timothy Arthur Chandos Snow +13 more
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HLA DR antigens and gold toxicity. [PDF]
Annals of the Rheumatic Diseases, 1983 One hundred and thirty-two patients with rheumatoid arthritis treated with gold have been studied for possible associations between HLA DR antigens and different adverse reactions occurring during such therapy. Patients possessing HLA DR3 had a significantly greater frequency of side effects than patients lacking this antigen.
J T, Gran, G, Husby, E, Thorsby
openaire +4 more sources
Increased HLA-DR Expression on M2a Monocytes and Helper T Cells in Patients with COPD and Asthma–COPD Overlap Contributes to Disease Severity via Apoptosis and ROS [PDF]
AntioxidantsObjective: Ongoing debates focus on the role of human leukocyte antigen (HLA) class II expression in shaping clinical phenotypes of chronic inflammatory airway diseases.
Yung-Che Chen +8 more
doaj +2 more sources
Human leukocyte antigen variation among Iranian renal transplant recipients [PDF]
Journal of Nephropathology, 2012 Background: HLA typing analysis is important in renal transplant patients. Objectives: We made a plan to determine the most frequent HLA antigens in Iranian kidney transplant patients.
Behzad Einollahi +2 more
doaj +1 more source
Cell Reports, 2023 Summary: Subunit vaccines typically require co-administration with an adjuvant to elicit protective immunity, adding development hurdles that can impede rapid pandemic responses.
Audrey Kassardjian +11 more
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Frontiers in Immunology, 2022 Common human coronaviruses have been circulating undiagnosed worldwide. These common human coronaviruses share partial sequence homology with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); therefore, T cells specific to human coronaviruses
You-Seok Hyun +11 more
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Current research status of HLA in immune‐related diseases
Immunity, Inflammation and Disease, 2021 Human leukocyte antigen (HLA), also known as human major histocompatibility complex (MHC), is encoded by the HLA gene complex, and is currently known to have the highest gene density and the most polymorphisms among human chromosomal areas.
Bingnan Liu, Yuanyuan Shao, Rong Fu
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