Results 141 to 150 of about 114,761 (352)

Mapping of the genes encoding the HLA-DR alpha chain and the HLA-related antigens to a chromosome 6 deletion by using genomic blotting.

, 1983
M Kellis, D Stetler, Randall K. Saiki, P Gladstone, Donald Pious   +4 more
openalex   +2 more sources

Oesophageal Epithelial Cell‐Intrinsic MHCII Regulates Food Antigen‐Dependent Eosinophilic Esophagitis in an IFNγ‐Dependent Manner

Clinical &Experimental Allergy, EarlyView.
We found that oesophageal epithelial cells upregulate MHCII expression during active EoE in humans and a mouse model. MHCII expression by EECs was governed by IFNγ‐inducible transcriptional elements. EEC‐intrinsic MHCII promoted regulatory T cell accumulation and attenuated eosinophilic oesophageal inflammation.
Eric M. Rodríguez‐López, Rachel L. Clement, Megha Lal, Yusen Zhou, Stephen D. Carro, Charles‐Antoine Assenmacher, Ravi Gautam, Jarad Beers, Amanda B. Muir, Jonathan M. Spergel, Melanie A. Ruffner, Laurence C. Eisenlohr, David A. Hill   +12 more
wiley   +1 more source

Investigating age-related dynamics and transcriptional signatures of CD8⁺HLA-DR⁺ regulatory T lymphocytes: perspectives in understanding immune system aging

Медицинская иммунология
The ability of the CD8+HLA-DR+ regulatory T lymphocytes population to regulate the immune response was first described several years ago. It is known that the suppressive effects of these cells depend on intercellular interactions and are mediated by the
K. S. Matveeva, S. A. Rybtsov, D. V. Shevyrev   +2 more
doaj   +1 more source

Ultrastructural Documentation of HLA-DR Antigen Reactivity in Normal Human Acrosyringial Epithelium

, 1983
Gëorge F. Murphy, Richard S. Shepard, Terence J. Harrist, Ben R. Bronstein, Atul K. Bhan   +4 more
openalex   +1 more source

Aberrant expression of HLA-DR antigen in diffuse sclerosing variant of papillary carcinoma of thyroid. [PDF]

, 1989
Xavier Matías‐Guiu, Jordi Esquius
openalex   +1 more source

Alternative Polyadenylation Drives Runaway Pro‐Inflammatory Macrophages in Periodontitis by Enabling Escape From miRNA Repression

Cell Proliferation, EarlyView.
APA‐Guided Therapeutic miRNA Selection for Periodontitis. ABSTRACT Periodontitis is a chronic inflammatory disease driven by a dysregulated host immune response, in which macrophage‐mediated inflammation shifts from protective to pathological. While monocyte‐derived macrophages (MDMs) are known to adopt a destructive, M1‐like pro‐inflammatory phenotype,
Jing Zhang, Yilong Zhao, Jiaru Deng, Shuyuan Qu, Yiyi Zhou, Qin Zhao, Yufeng Zhang   +6 more
wiley   +1 more source

NOD2 (Nucleotide-Binding Oligomerization Domain-Containing Protein 2)-Mediated Modulation of the Immune Response Induced by BCG (Bacillus Calmette-Guérin) Bacilli

Pathogens
The Bacillus Calmette-Guérin (BCG) vaccine confers broad, non-specific immunity that may bolster defenses against respiratory viruses. While NOD2 (nucleotide-binding oligomerization domain-containing protein 2)-driven pathways are central to innate ...
Magdalena Jurczak, Joanna Kaczmarek, Magdalena Kowalewska-Pietrzak, Paulina Stelmach, Magdalena Druszczynska   +4 more
doaj   +1 more source

Engaging the Immune Response to Normalize the Tumor Microenvironment [PDF]

, 2013
Solid tumors exist as heterogeneous populations comprised not only of malignant cells, but various other cell types, including cells that make up the vasculature, that can strongly influence tumorgenicity.
Sabins, Nina, Storkus, Walter
core  

Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen [PDF]

, 1987
Denise Gay, Paul J. Maddon, Rafick‐Pierre Sékaly, Mary Anne Talle, Maurice Godfrey, Eric O. Long, Gideon Goldstein, Leonard Chess, Richard Axel, John W. Kappler, Philippa Marrack   +10 more
openalex   +1 more source

A UK key opinion leader perspective: Navigating the immunological and logistical transformation brought by stem cell‐derived islets for the treatment of type 1 diabetes

Diabetic Medicine, EarlyView.
Abstract Aims To explore UK key‐opinion leader perspectives on the future role of stem cell‐derived islets (sc‐islets) in islet transplantation for people with type 1 diabetes (T1D). Methods Four UK‐based key‐opinion leaders evaluated current limitations of donor islet transplantation and reviewed emerging evidence, clinical pathways and logistical ...
Thomas Strakosch, Shareen Forbes
wiley   +1 more source