Results 21 to 30 of about 114,761 (352)

The Immunogenicity of HLA Class II Mismatches: The Predicted Presentation of Nonself Allo-HLA-Derived Peptide by the HLA-DR Phenotype of the Recipient Is Associated with the Formation of DSA

Journal of Immunology Research, 2017
The identification of permissible HLA class II mismatches can prevent DSA in mismatched transplantation. The HLA-DR phenotype of recipients contributes to DSA formation by presenting allo-HLA-derived peptides to T-helper cells, which induces the ...
Vadim Jucaud
doaj   +1 more source

Donor HLA−DR Drives the Development of De Novo Autoimmunity Following Lung and Heart Transplantation

Transplantation Direct, 2020
Background. Individuals harbor preexisting HLA−DR/DQ−restricted responses to collagen type V (ColV) mediated by Th17 cells under Treg control, both specific to peptides that bind to inherited HLA class II antigens. Yet after transplant, the donor−DR type
Ewa Jankowska−Gan, MS, Vrushali V. Agashe, PhD, Diego A. Lema, MD, Ying Zhou, MS, Laura Gonzalez Bosc, PhD, Jeremy A. Sullivan, PhD, Daniel S. Greenspan, PhD, William J. Burlingham, PhD   +7 more
doaj   +1 more source

Immunological Compatibility Status of Placenta-Derived Stem Cells is Mediated by Scaffold 3D Structure [PDF]

, 2018
Placenta-derived amniotic epithelial cells (AECs), a great cell source for tissue engineering and stem cell therapy, are immunologically inert in their native state; however, immunological changes in these cells after culture and differentiation have ...
Azizian, Sara, Bahrami, Soheyl, Katami, Fatemeh, Modaresifar, Khashayar, Mosaffa, Nariman, Niknejad, Hassan, Peirovi, Habibollah, Redl, Heinz, Tayebi, Lobat   +8 more
core   +2 more sources

HLA-DR antigen-negative acute myeloid leukemia [PDF]

Leukemia, 2003
Human leukocyte antigen (HLA) Class II antigens are variably expressed on acute myeloid leukemia (AML) blasts. The biological and clinical significance of HLA Class II antigen expression by AML cells is not known. Therefore, we sought to characterize cases of AML without detectable HLA-DR expression. Samples from 248 consecutive adult AML patients were
M, Wetzler, B K, McElwain, C C, Stewart, L, Blumenson, A, Mortazavi, L A, Ford, J L, Slack, M, Barcos, S, Ferrone, M R, Baer   +9 more
openaire   +2 more sources

The role of HLA-DP mismatches and donor specific HLA-DP antibodies in kidney transplantation : a case series [PDF]

, 2021
BACKGROUND: The impact of HLA-DP mismatches on renal allograft outcome is still poorly understood and is suggested to be less than that of the other HLA loci.
Abramowicz, D, Claas, FHJ, Daniëls, L, Edmonds, MP, Hellemans, R, Kramer, CSM, Naessens, M, Senev, A, Van Laecke, Steven, Vanden Driessche, M   +9 more
core   +2 more sources

HLA‐DR antigens in gold‐induced neutropenia [PDF]

Arthritis & Rheumatism, 1986
We studied the clinical courses of 9 patients who developed acute gold-induced neutropenia with marrow aplasia. Eight of these carried HLA-DR4, compared with only 2 of 9 who had mild, chronic, isolated neutropenia (P less than 0.05). Only 1 of 9 patients with myelotoxicity carried HLA-DR3.
S, Aaron, P, Davis, J, Bertouch
openaire   +2 more sources

CD4+ Th immunogenicity of the Ascaris spp. secreted products [PDF]

, 2020
Ascaris spp. is a major health problem of humans and animals alike, and understanding the immunogenicity of its antigens is required for developing urgently needed vaccines.
Bertazzon, Miriam, Ebner, Friederike, Freund, Christian, Hartmann, Susanne, Midha, Ankur, Morrison, Eliot, Álvaro-Benito, Miguel   +6 more
core   +1 more source

FREQUENCY OF OCCURRENCE OF ANTIBODIES TO HLA ANTIGENS IN RECIPIENTS ON THE WAITING LIST FOR KIDNEY TRANSPLANTATION

Медицина в Кузбассе, 2023
Antibodies (a/t) to antigens (a/g) of human tissue compatibility HLA (human leucocyte antigens) are the main cause of kidney transplant rejection. Antigens of the HLAI class system (loci A, B, C) are present on all nucleated cells of the body, HLA class
Елена Борисовна Лукоянычева, Алия Зинфировна Барканова, Григорий Валерьевич Вавин, Светлана Ивановна Елгина, Вадим Гельевич Мозес, Елена Владимировна Рудаева, Кира Борисовна Мозес, Наталья Степановна Черных   +7 more
doaj  

Human-leukocyte antigen typing in Javanese patients with recurrent aphthous stomatitis

Dental Journal, 2010
Background: Recurrent aphthous stomatitis (RAS) is a common oral disorder that despite extensive researches, the etiology of this phenomenon is still unknown.
Diah Savitri Ernawati, Bagus Soebadi, Desiana Radithia   +2 more
doaj   +1 more source

ASSOTIATIONS OF PECULIARITIES OF HLA-PHENOTYPE AND THE SENSIBILITY TO THE CORTICOSTEROID TREATMENT IN PATIENTS WITH CHRONIC GLOMERULONEPHRITIS WITH NEPHROTIC SYNDROME

Український Журнал Нефрології та Діалізу, 2017
The purpose of study was determination of HLA -antigens I and II classes as predictors of ineffectiveness of initial steroid therapy, and according prognozonegative markers of chronic glomerulonephritis with nephrotic syndrome. Methods. In 59 chronic
M. Kolesnyk, G. Drannik, V. Driyanska, O. Petrina, M. Velychko   +4 more
doaj   +1 more source