Results 31 to 40 of about 12,878,485 (338)
The Impact of HLA-G and HLA-E Polymorphisms on CMV Reinfection in Liver Transplant Recipients [PDF]
Iranian Journal of Immunology, 2022 Background: Cytomegalovirus (CMV) reinfection in transplant patients has been associated with graft loss and decreased patient survival. In this regard, the HLA-G molecule has the immunomodulatory characteristic and its soluble isoforms have important ...
Masumeh Darai +5 more
doaj +1 more source
Intratumor Heterogeneity of HLA-G Expression in Cancer Lesions
Frontiers in Immunology, 2020 Signaling pathway between human leukocyte antigen (HLA)-G and immune inhibitory receptors immunoglobulin-like transcript (ILT)-2/4 has been acknowledged as one of immune checkpoints, and as a potential target for cancer immunotherapy.
Xia Zhang +9 more
doaj +1 more source
International Journal of Molecular Sciences, 2021 The human G-leukocyte antigen (HLA-G) molecule is a non-classical major histocompatibility complex (MHC) class I molecule. The pertinence of HLA-G has been investigated in numerous studies which have sought to elucidate the relevance of HLA-G in ...
Monika Zaborek-Łyczba +7 more
semanticscholar +1 more source
MiRNA-mediated control of HLA-G expression and function. [PDF]
PLoS ONE, 2012 HLA-G is a non-classical HLA class-Ib molecule expressed mainly by the extravillous cytotrophoblasts (EVT) of the placenta. The expression of HLA-G on these fetal cells protects the EVT cells from immune rejection and is therefore important for a healthy
Irit Manaster +7 more
doaj +1 more source
A Critical Assessment of the Association between HLA-G Expression by Carcinomas and Clinical Outcome
International Journal of Molecular Sciences, 2021 Human leukocyte antigen-G (HLA-G) conveys immunological tolerance at the maternal-foetal interface. HLA-G expression by tumour cells may also play such a role, resulting in tumour immune evasion, making HLA-G a potential target for immunotherapies.
R. van de Water +4 more
semanticscholar +1 more source
HLA-G: A New Immune Checkpoint in Cancer?
International Journal of Molecular Sciences, 2020 Human leukocyte antigen G (HLA-G), known as a central protein in providing immune tolerance to the fetus in pregnant women, is also studied for a possible role in tumor development.
D. Krijgsman +4 more
semanticscholar +1 more source
A distant trophoblast-specific enhancer controls HLA-G expression at the maternal–fetal interface [PDF]
, 2016 HLA-G, a nonclassical HLA molecule uniquely expressed in the placenta, is a central component of fetus-induced immune tolerance during pregnancy. The tissue-specific expression of HLA-G, however, remains poorly understood.
Camahort, Raymond +12 more
core +1 more source
HLA, 2020 Polymorphic sites in the HLA‐G gene may influence expression and function of the protein. Knowledge of the association between high‐resolution HLA‐G alleles and 3‐prime untranslated (3′UTR) haplotypes is useful for studies on the role of HLA‐G in ...
J. Drabbels +9 more
semanticscholar +1 more source
HLA-G Expression in Lung Adenocarcinoma Tissues and Its Relationship with Prognosis
Zhongliu Fangzhi Yanjiu, 2018 Objective To investigate the expression of HLA-G and determine the prognostic value of HLA-G for lung adenocarcinoma. Methods The genomic alternation of HLA-G was analyzed using cBioPortal analytic tool.
ZHANG Wenlong +4 more
doaj +1 more source
HLA-G Expression Pattern: Reliable Assessment for Pregnancy Outcome Prediction [PDF]
Advanced Pharmaceutical Bulletin, 2013 Because mothers and fathers are more or less dissimilar at multiple HLA loci, mother considers her fetus as a semi-allograft. Mother's immune system may recognize paternal HLA as foreign antigen and may develop anti-paternal HLA antibodies and cytotoxic ...
Elnaz Mosaferi +5 more
doaj +1 more source