Results 11 to 20 of about 170,658 (215)
The Impact of HLA-G and HLA-E Polymorphisms on CMV Reinfection in Liver Transplant Recipients [PDF]
Iranian Journal of Immunology, 2022 Background: Cytomegalovirus (CMV) reinfection in transplant patients has been associated with graft loss and decreased patient survival. In this regard, the HLA-G molecule has the immunomodulatory characteristic and its soluble isoforms have important ...
Masumeh Darai +5 more
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Intratumor Heterogeneity of HLA-G Expression in Cancer Lesions
Frontiers in Immunology, 2020 Signaling pathway between human leukocyte antigen (HLA)-G and immune inhibitory receptors immunoglobulin-like transcript (ILT)-2/4 has been acknowledged as one of immune checkpoints, and as a potential target for cancer immunotherapy.
Xia Zhang +9 more
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MiRNA-mediated control of HLA-G expression and function. [PDF]
PLoS ONE, 2012 HLA-G is a non-classical HLA class-Ib molecule expressed mainly by the extravillous cytotrophoblasts (EVT) of the placenta. The expression of HLA-G on these fetal cells protects the EVT cells from immune rejection and is therefore important for a healthy
Irit Manaster +7 more
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Association of HLA-A and Non-Classical HLA Class I Alleles.
PLoS ONE, 2016 The HLA-A locus is surrounded by HLA class Ib genes: HLA-E, HLA-H, HLA-G and HLA-F. HLA class Ib molecules are involved in immuno-modulation with a central role for HLA-G and HLA-E, an emerging role for HLA-F and a yet unknown function for HLA-H.
Federico Carlini +8 more
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HLA-G Expression in Lung Adenocarcinoma Tissues and Its Relationship with Prognosis
Zhongliu Fangzhi Yanjiu, 2018 Objective To investigate the expression of HLA-G and determine the prognostic value of HLA-G for lung adenocarcinoma. Methods The genomic alternation of HLA-G was analyzed using cBioPortal analytic tool.
ZHANG Wenlong +4 more
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HLA-G Expression Pattern: Reliable Assessment for Pregnancy Outcome Prediction [PDF]
Advanced Pharmaceutical Bulletin, 2013 Because mothers and fathers are more or less dissimilar at multiple HLA loci, mother considers her fetus as a semi-allograft. Mother's immune system may recognize paternal HLA as foreign antigen and may develop anti-paternal HLA antibodies and cytotoxic ...
Elnaz Mosaferi +5 more
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HLA-G Genotype/Expression/Disease Association Studies: Success, Hurdles, and Perspectives
Frontiers in Immunology, 2020 The non-classical HLA-G is a well-known immune-modulatory molecule. In physiological condition, HLA-G surface expression is restricted to the maternal–fetal interface and to immune-privileged adult tissues, whereas soluble forms of HLA-G are detectable ...
Giada Amodio, Silvia Gregori
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Tolerogenic function of dimeric forms of HLA-G recombinant proteins: a comparative study in vivo. [PDF]
PLoS ONE, 2011 HLA-G is a natural tolerogenic molecule involved in the best example of tolerance to foreign tissues there is: the maternal-fetal tolerance. The further involvement of HLA-G in the tolerance of allogeneic transplants has also been demonstrated and some ...
Benoit Favier +7 more
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Expression of HLA-G in patients with B-cell chronic lymphocytic leukemia (B-CLL).
Folia Histochemica et Cytobiologica, 2009 The expression of HLA-G was reported in certain malignancies and its role in escaping from immunosurveillance in cancers was proposed since HLA-G is a nonconventional HLA class I molecule that protects fetus from immunorecognition during pregnancy ...
M Schmitt +4 more
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Frontiers in Immunology, 2021 Human leukocyte antigen G (HLA-G) is known as a novel immune checkpoint molecule in cancer; thus, HLA-G and its receptors might be targets for immune checkpoint blockade in cancer immunotherapy.
Hui-Hui Xu +6 more
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