Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by D94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis [PDF]
, 1998 Human histocompatibility leukocyte antigen (HLA)-E is a nonclassical HLA class I molecule, the gene for which is transcribed in most tissues. It has recently been reported that this molecule binds peptides derived from the signal sequence of HLA class I ...
John E. Coligan +14 more
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HLA-G Expression in Lung Adenocarcinoma Tissues and Its Relationship with Prognosis
Zhongliu Fangzhi Yanjiu, 2018 Objective To investigate the expression of HLA-G and determine the prognostic value of HLA-G for lung adenocarcinoma. Methods The genomic alternation of HLA-G was analyzed using cBioPortal analytic tool.
ZHANG Wenlong +4 more
doaj +1 more source
HLA-G Expression Pattern: Reliable Assessment for Pregnancy Outcome Prediction [PDF]
Advanced Pharmaceutical Bulletin, 2013 Because mothers and fathers are more or less dissimilar at multiple HLA loci, mother considers her fetus as a semi-allograft. Mother's immune system may recognize paternal HLA as foreign antigen and may develop anti-paternal HLA antibodies and cytotoxic ...
Elnaz Mosaferi +5 more
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Association of HLA-A and Non-Classical HLA Class I Alleles.
PLoS ONE, 2016 The HLA-A locus is surrounded by HLA class Ib genes: HLA-E, HLA-H, HLA-G and HLA-F. HLA class Ib molecules are involved in immuno-modulation with a central role for HLA-G and HLA-E, an emerging role for HLA-F and a yet unknown function for HLA-H.
Federico Carlini +8 more
doaj +1 more source
HLA-G Genotype/Expression/Disease Association Studies: Success, Hurdles, and Perspectives
Frontiers in Immunology, 2020 The non-classical HLA-G is a well-known immune-modulatory molecule. In physiological condition, HLA-G surface expression is restricted to the maternal–fetal interface and to immune-privileged adult tissues, whereas soluble forms of HLA-G are detectable ...
Giada Amodio, Silvia Gregori
doaj +1 more source
HLA‐Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy [PDF]
, 2008 We assessed the influence of human leukocyte antigen (HLA) alleles HLA-Bw4 and HLA-Bw6 on CD4 T cell recovery after starting successful combination antiretroviral therapy in 265 individuals. The median gains in the CD4 T cell count after 4 years were 258
Battegay, Manuel +42 more
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Expression of HLA-G in patients with B-cell chronic lymphocytic leukemia (B-CLL).
Folia Histochemica et Cytobiologica, 2009 The expression of HLA-G was reported in certain malignancies and its role in escaping from immunosurveillance in cancers was proposed since HLA-G is a nonconventional HLA class I molecule that protects fetus from immunorecognition during pregnancy ...
M Schmitt +4 more
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Tolerogenic function of dimeric forms of HLA-G recombinant proteins: a comparative study in vivo. [PDF]
PLoS ONE, 2011 HLA-G is a natural tolerogenic molecule involved in the best example of tolerance to foreign tissues there is: the maternal-fetal tolerance. The further involvement of HLA-G in the tolerance of allogeneic transplants has also been demonstrated and some ...
Benoit Favier +7 more
doaj +1 more source
The role of HLA-B27 in inflammatory arthritis [PDF]
, 2009 Redacted electronic version excludes material for which permission has not been granted by the rights holderThe MHC class I allele, HLA-B27, is strongly associated with a group of inflammatory arthritic conditions collectively known as ...
Lynch, Sarah Janice
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Role of HLA-G in Viral Infections
Frontiers in Immunology, 2022 The human leukocyte antigen (HLA)-G is a non-classical HLA class I molecule, which has distinct features to classical HLA-A, -B, -C antigens, such as a low polymorphism, different splice variants, highly restricted, tightly regulated expression and ...
Simon Jasinski-Bergner +4 more
doaj +1 more source