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Polimorfismos da região 3' não traduzida do gene HLA-G em pacientes com câncer de mama e controles no estado de Santa Catarina [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Biologia Celular e do DesenvolvimentoO câncer de mama é o segundo tipo de câncer mais frequente no mundo e de maior prevalência ...
Silva, Mariáh Damiani da
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HLA-H, HLA-A and HLA-G signal sequence alignment. Variable amino-acid positions among loci are highlighted in bold.

, 2016
HLA-H, HLA-A and HLA-G signal sequence alignment. Variable amino-acid positions among loci are highlighted in bold.
Julie Di Cristofaro (473988), Jacques Chiaroni (473993), Audrey Tous (3192987), Stéphane Buhler (149592), Virginia Ferreira (3192984), Céline René (10829), Jean-François Eliaou (273686), Federico Carlini (501365), Christophe Picard (501369)   +8 more
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The role of HLA-G molecule and HLA-G gene polymorphisms in tumors, viral hepatitis and parasitic diseases

Frontiers in Immunology, 2015
Considering that the non-classical HLA-G molecule has well-recognized tolerogenic properties, HLA-G expression is expected to be deleterious when present in tumor cells and in cells chronically infected by viruses, whereas HLA-G expression is expected to
Fabrício César Dias, Erick C. Castelli, Cristhianna Viesti Advincula Collares, Philippe eMoreau, Eduardo Antonio Donadi   +4 more
doaj   +1 more source

Co-expression of HLA-E and HLA-G on genetically modified porcine endothelial cells attenuates human NK cell-mediated degranulation

Frontiers in Immunology, 2023
Natural killer (NK) cells play an important role in immune rejection in solid organ transplantation. To mitigate human NK cell activation in xenotransplantation, introducing inhibitory ligands on xenografts via genetic engineering of pigs may protect the
Arthur A. Cross-Najafi, Kristine Farag, Abdulkadir Isidan, Wei Li, Wenjun Zhang, Zhansong Lin, Julia R. Walsh, Kevin Lopez, Yujin Park, Nancy G. Higgins, David K.C. Cooper, Burcin Ekser, Ping Li   +12 more
doaj   +1 more source

Characterization of the expression and immunological impact of the transcriptional activator CREB in renal cell carcinoma

Journal of Translational Medicine, 2020
Background The non-classical human leukocyte antigen (HLA)-G is a strong immunomodulatory molecule. Under physiological conditions, HLA-G induces immunological tolerance in immune privileged tissues, while under pathophysiological situations it ...
Michael Friedrich, Christine Stoehr, Simon Jasinski-Bergner, Arndt Hartmann, Sven Wach, Bernd Wullich, André Steven, Barbara Seliger   +7 more
doaj   +1 more source

HLA-G 14 bp In/Del and +3142 C/G genotypes are differentially expressed between patients with grade IV gliomas and controls

, 2020
Aim: Human Leukocyte Antigen-G (HLA-G) is a non-classical class I molecule that is involved in maternal–fetal immunotolerance. In cancer, this molecule contributes to the tumor escape.
Renata T. Simões (8663925), Ibrahim Sadissou (3043410), Marcelo A. Buzellin (8663907), Luciene S. Tafuri (8663910), Nathália A. Gomes (8663901), Istéfani Luciene da Silva (8663922), Cristiana B. Nunes (8663913), Eduardo A. Donadi (8663919), Kênia Cristina S.F. de Magalhães (8663895), Gérvasio T. Carvalho (8663904), Maurício B. Nunes (8663916), Karla R. Silva (8663898)   +11 more
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HLA-G Dimers in the Prolongation of Kidney Allograft Survival

Journal of Immunology Research, 2014
Human leukocyte antigen-G (HLA-G) contributes to acceptance of allografts in solid organ/tissue transplantation. Most studies have determined that soluble HLA-G isoforms are systematically detected in serum/plasma of transplanted patients with ...
Maureen Ezeakile, Vera Portik-Dobos, Juan Wu, Daniel D. Horuzsko, Rajan Kapoor, Muralidharan Jagadeesan, Laura L. Mulloy, Anatolij Horuzsko   +7 more
doaj   +1 more source

HLA‐G: Function, polymorphisms and pathology

, 2020
HLA-G immune modulatory genes and molecules are presently being studied by a widespread number of research groups. In the present study, we do not aim to be exhaustive since the number of manuscripts published every year is overwhelming. Instead, our aim
López‐Nares, Adrián, Vaquero Yuste, Christian, Palacio‐Gruber, Jose, Suarez‐Trujillo, Fabio, Martín Villa, José Manuel, Juárez Martín-Delgado, Ignacio, Arnaiz Villena, Antonio   +6 more
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HLA-G expression in peritumoral fundic gland mucous neck cells, but not in tumor lesions, related to poor survival in patients with gastric cancer

Frontiers in Immunology
IntroductionThe concept that human leukocyte antigen-G (HLA-G) expression is specifically in various malignant lesions but absent in adjacent normal tissues has been well documented, and HLA-G is acknowledged as a novel immune checkpoint.MethodsIn this ...
Xia Zhang, Xia Zhang, Qiu-Yue Han, Qiu-Yue Han, Jian-Gang Zhang, Jian-Gang Zhang, Wei-Hua Yan, Wei-Hua Yan, Wei-Hua Yan, Aifen Lin, Aifen Lin, Aifen Lin   +11 more
doaj   +1 more source

Análise dos polimorfismos da região 3’ não traduzida do gene hla-g e inserção aluyhg com a manifestação do lúpus eritematoso sistêmico na população do estado de Santa Catarina [PDF]

, 2012
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.O lúpus eritematoso sistêmico é uma doença inflamatória crônica de caráter autoimune, multissistêmica, remitente e recidivante, sendo caracterizada por ...
Karasiak, Gabriela Duarte
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