Results 61 to 70 of about 11,789,754 (116)

Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection [PDF]

open access: yes, 2006
Cellular immune responses are an important correlate of hepatitis C virus (HCV) infection outcome. These responses are governed by the host's human leukocyte antigen (HLA) type, and HLA-restricted viral escape mutants are a critical aspect of this host ...
Cheng, Wendy   +70 more
core   +1 more source

HLA-G:: ¿molécula inductora de inmunotolerancia? HLA-G molecule as inductor of immunotolerance

open access: yesRevista Cubana de Hematología, Inmunología y Hemoterapia, 2009
Las moléculas HLA-G son antígenos HLA de clase I "no clásicos" del sistema principal de histocompatibilidad. Existen 6 isoformas del gen HLA-G que codifican 4 proteínas unidas a membrana (HLA-G1, HLA-G2, HLA-G3, HLA-G4) y 3 isoformas solubles (HLA-G5 ...
Dra. María E. Alfonso Valdés
doaj  

Replication of the association of HLA-B7 with Alzheimer's disease: a role for homozygosity? [PDF]

open access: yes, 2006
Background: There are reasons to expect an association with Alzheimer's disease (AD) within the HLA region. The HLA-B & C genes have, however, been relatively understudied.
Smith, AD   +30 more
core   +1 more source

HLA-G Expression Is an Independent Predictor for Improved Survival in High Grade Ovarian Carcinomas

open access: yesJournal of Immunology Research, 2014
Aberrant expression of human leukocyte antigens (HLA) class I has prognostic importance in various cancers. Here, we evaluated the prognostic value of classical (A/B/C) and nonclassical (G/E) HLA expression in 169 high grade epithelial ovarian cancer ...
M. J. Rutten   +6 more
doaj   +1 more source

The Dual Role of HLA-G in Cancer

open access: yesJournal of Immunology Research, 2014
We here review the current data on the role of HLA-G in cancer based on recent findings of an unexpected antitumor activity of HLA-G in hematological malignancies.
Nathalie Rouas-Freiss   +3 more
doaj   +1 more source

Molecular Pathways: Human leukocyte antigen G (HLA-G).

open access: yes, 2013
Human leukocyte antigen G (HLA-G) is a non-classical major histocompatibility complex (MHC) class I molecule that exerts important tolerogenic functions.
Carmen Criscitiello   +11 more
core   +1 more source

Expression of HLA-G in the Skin of Patients with Pemphigus Vulgaris

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2008
Studies on HLA-G, a nonpolymorphic antigen of non-classical HLA class I, is of basic and clinical significance. In the present study, the expression of HLA-G proteins in the human skin tissue sections of normal and autoimmune pemphigus vulgaris (PV ...
Fathemeh Yari   +5 more
doaj  

The role of methylation, DNA polymorphisms and microRNAs on HLA-G expression in human embryonic stem cells

open access: yesStem Cell Research, 2017
The human leukocyte antigen (HLA)-G gene seems to play a pivotal role in maternal tolerance to the fetus. Little is known about HLA-G expression and its molecular control during in vivo human embryogenesis.
A. Verloes   +7 more
doaj   +1 more source

HLA-B*5701 screening for hypersensitivity to Abacavir [PDF]

open access: yes, 2008
Background Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele. This study was designed to establish the effectiveness of prospective HLA-B*5701 screening to prevent the hypersensitivity reaction to ...
Jagel-Guedes, E.   +17 more
core  

Udvikling og optimering af protokol til ‘knockdown’ af HLA-G med siRNA på JEG-3 choriocarcinom cellelinie: Design and optimization of protocol for knockdown of HLA-G using siRNA on JEG-3 choriocarcinoma cell line [PDF]

open access: yes, 2015
The expression of human leucocyte antigen-G (HLA-G) in trophoblasts plays a crucial role in the achievement of a successful pregnancy. HLA-G is believed to possess an immune modulating effect which protects the fetus from being attacked by the mother's ...
Christensen, Jane Lind, Hancke, Sandra
core   +1 more source

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