Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection [PDF]
Cellular immune responses are an important correlate of hepatitis C virus (HCV) infection outcome. These responses are governed by the host's human leukocyte antigen (HLA) type, and HLA-restricted viral escape mutants are a critical aspect of this host ...
Cheng, Wendy +70 more
core +1 more source
HLA-G:: ¿molécula inductora de inmunotolerancia? HLA-G molecule as inductor of immunotolerance
Las moléculas HLA-G son antígenos HLA de clase I "no clásicos" del sistema principal de histocompatibilidad. Existen 6 isoformas del gen HLA-G que codifican 4 proteínas unidas a membrana (HLA-G1, HLA-G2, HLA-G3, HLA-G4) y 3 isoformas solubles (HLA-G5 ...
Dra. María E. Alfonso Valdés
doaj
Replication of the association of HLA-B7 with Alzheimer's disease: a role for homozygosity? [PDF]
Background: There are reasons to expect an association with Alzheimer's disease (AD) within the HLA region. The HLA-B & C genes have, however, been relatively understudied.
Smith, AD +30 more
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HLA-G Expression Is an Independent Predictor for Improved Survival in High Grade Ovarian Carcinomas
Aberrant expression of human leukocyte antigens (HLA) class I has prognostic importance in various cancers. Here, we evaluated the prognostic value of classical (A/B/C) and nonclassical (G/E) HLA expression in 169 high grade epithelial ovarian cancer ...
M. J. Rutten +6 more
doaj +1 more source
The Dual Role of HLA-G in Cancer
We here review the current data on the role of HLA-G in cancer based on recent findings of an unexpected antitumor activity of HLA-G in hematological malignancies.
Nathalie Rouas-Freiss +3 more
doaj +1 more source
Molecular Pathways: Human leukocyte antigen G (HLA-G).
Human leukocyte antigen G (HLA-G) is a non-classical major histocompatibility complex (MHC) class I molecule that exerts important tolerogenic functions.
Carmen Criscitiello +11 more
core +1 more source
Expression of HLA-G in the Skin of Patients with Pemphigus Vulgaris
Studies on HLA-G, a nonpolymorphic antigen of non-classical HLA class I, is of basic and clinical significance. In the present study, the expression of HLA-G proteins in the human skin tissue sections of normal and autoimmune pemphigus vulgaris (PV ...
Fathemeh Yari +5 more
doaj
The human leukocyte antigen (HLA)-G gene seems to play a pivotal role in maternal tolerance to the fetus. Little is known about HLA-G expression and its molecular control during in vivo human embryogenesis.
A. Verloes +7 more
doaj +1 more source
HLA-B*5701 screening for hypersensitivity to Abacavir [PDF]
Background Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele. This study was designed to establish the effectiveness of prospective HLA-B*5701 screening to prevent the hypersensitivity reaction to ...
Jagel-Guedes, E. +17 more
core
Udvikling og optimering af protokol til ‘knockdown’ af HLA-G med siRNA på JEG-3 choriocarcinom cellelinie: Design and optimization of protocol for knockdown of HLA-G using siRNA on JEG-3 choriocarcinoma cell line [PDF]
The expression of human leucocyte antigen-G (HLA-G) in trophoblasts plays a crucial role in the achievement of a successful pregnancy. HLA-G is believed to possess an immune modulating effect which protects the fetus from being attacked by the mother's ...
Christensen, Jane Lind, Hancke, Sandra
core +1 more source

