Results 81 to 90 of about 11,789,754 (116)

The HLA factsbook /

, 2000
The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner and expert alike. The focus of the book is on the polymorphic HLA genes (HLA-A, B, C, DP, DQ, and DR) that are typed for ...
Parham, Peter, Marsh, Steven G. E., Barber, Linda D.   +2 more
core  

The non-classical immune checkpoint HLA-G: a regulatory master switch governing tolerance, evasion, and translational frontiers

Frontiers in Oncology
Human Leukocyte Antigen G (HLA-G), a non-classical MHC Class I molecule, plays a pivotal role in immune regulation, particularly in reproductive immunology.
Huan Liu, Qiong Li, Junli Li, Ying Xue, Xiaofei Xue, Pingping Xu   +5 more
doaj   +1 more source

Discovery of the HLA-DQB1*06:465 allele, a variant of HLA-DQB1*06:04:01:01

HLA-DQB1*06:465 differs from HLA-DQB1*06:04:01:01 by a non-synonymous nucleotide substitution in codon ...
John Jeongseok Yang, Heung-Bum Oh
core   +1 more source

Human leukocyte antigen-G isoform HLA-G2/6, but not HLA-G1/4/5, is an independent indicator of poor survival in patients with colorectal cancer

Frontiers in Immunology
BackgroundHuman leukocyte antigen (HLA)-G has multiple isoforms with unique molecular structures and receptor-binding specificities. Different HLA-G isoform(s) may have distinct clinical relevance.
Xia Zhang, Xia Zhang, Qiu-Yue Han, Qiu-Yue Han, Jian-Gang Zhang, Jiao Lin, Wei-Hua Yan, Wei-Hua Yan, Wei-Hua Yan, Aifen Lin, Aifen Lin, Aifen Lin   +11 more
doaj   +1 more source

HLA-G may predict the disease course in patients with early arthritis

, 2012
The current management of early arthritis (EA) with negative prognostic factors is to start an intensive treatment. To avoid under/overtreatment, it is important to identify EA evolution biomarkers.
RIZZO, Roberta, FARINA, Ilaria, CIANCIO, GIovanni, DI LUCA, Dario, G. Ciancio, GALUPPI, Elisa, BORTOLOTTI, Daria, GOVONI, Marcello   +7 more
core  

Engineering HLA-G-targeted extracellular vesicles nanoplatform for enhanced cancer therapy through precise cancer drug delivery

Nature Communications
Extracellular vesicles (EVs) hold great potential as a therapeutic delivery system for cancer treatment. Here, we develop an innovative targeted drug delivery platform, human leukocyte antigen-G-VHH antibody-modified EV (α-HLA-G-EV), to enhance ...
Ming-You Shie, Shi-Wei Huang, Yeh Chen, Mei-Chih Chen, Chih-Ming Pan, Cheng-Yu Chen, Yen-Hong Lin, Min-Hua Yu, Kai-Wen Kan, Shao-Chih Chiu, Hui-Chun Ho, Yi-Wen Chen, Der-Yang Cho   +12 more
doaj   +1 more source

Human cytomegalovirus antigen presentation by HLA-G in infected cells

HLA-E and -G class Ib molecules were considered unrelated to viral antigen presentation. HLA-E binds nonamers from the leader sequences of other HLA-I molecules and the human cytomegalovirus (HCMV) UL40 protein, interacting with CD94/NKG2 NK cell ...
Fuchs, Jonas, Heredia, Gemma, Ataya, Michelle, Halenius, Anne, Muntasell i Castellví, Aura, 1972-, Ataya Fernández, Michelle, 1993-, Altadill, Mireia, López-Botet, Miguel, López-Botet, M. (Miguel), Alari‐Pahissa, Elisenda, Álvarez, Iñaki, Muntasell, Aura, Alari-Pahissa, Elisenda, Llano, Manuel, Vilches, Carlos, Hengel, Hartmut   +15 more
core   +1 more source

Antígenos de histocompatibilidad HLA-G y embarazo HLA-G histocompatibility antigens related to pregnancy

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2010
El componente HLA-G es una molécula clase I no clásica (Ib) del sistema principal de histocompatibilidad. Esta adopta 7 isoformas como resultado del empalme alternativo de un mismo RNA inmaduro; 4 se encuentran ligadas con la membrana (HLA-G1-G2-G3-G4) y
Luz M Morera Barrios, María E Alfonso Valdés, Catalino Ustáriz García, María de los A García García, Ana M Guerreiro Hernández, Rosa M Lam Díaz   +5 more
doaj  

Identification of the Novel HLA-DQB1*06:432 Allele by Sequence-Based Typing

HLA-DQB1*06:432 differs from HLA-DQB1*06:09:01:01 by a nonsynonymous nucleotide substitution in codon 186, changing Valine to ...
John Jeongseok Yang, Heung-Bum Oh
core   +1 more source

HLA-G polymorphisms and HLA-G expression in sarcoidosis

, 2006
BACKGROUND: The MHC class Ib molecule Human Leukocyte Antigen (HLA)-G may be important in induction and maintenance of immunological tolerance, and HLA-G expression may have a role in different cancers, in certain diseases with associations to HLA, and ...
Larsen, Lise Grupe, Hylenius, Sine, Jakobsen, Kirsten, Jensen, Michael S, Hviid, Thomas Vauvert F, Milman, Nils   +5 more
core   +1 more source