An expanding range of targets for kynurenine metabolites of tryptophan [PDF]
, 2013 The kynurenine pathway of tryptophan metabolism accounts for most of the tryptophan that is not committed to protein synthesis and includes compounds active in the nervous and immune systems.
Darlington, L. Gail +2 more
core +1 more source
Roles of HLA-G/KIR2DL4 in Breast Cancer Immune Microenvironment [PDF]
, 2022 Guoxu Zheng, Lintao Jia, Angang Yang
openalex +1 more source
Evaluation of Soluble Human Leukocyte Antigen-G (sHLA-G) Isoforms and Regulatory T Cells in Relapsing-Remitting Multiple Sclerosis. [PDF]
, 2015 Soluble forms of nonclassical human leukocyte antigen (HLA)-G have recently been suggested as immunomodulatory factors in multiple sclerosis (MS). HLA-G inhibits the effecter function of T cells and natural killer (NK) cells.
Alsahebfosoul, Fereshteh. +5 more
core +2 more sources
Impact of Human Immunodeficiency Virus in the Pathogenesis and Outcome of Patients with Glioblastoma Multiforme. [PDF]
, 2016 BackgroundImprovement in antiviral therapies have been accompanied by an increased frequency of non-Acquired Immune Deficiency Syndrome (AIDS) defining malignancies, such as glioblastoma multiforme.
Bui, Timothy T +5 more
core +1 more source
HLA-G:: ¿molécula inductora de inmunotolerancia? HLA-G molecule as inductor of immunotolerance
Revista Cubana de Hematología, Inmunología y Hemoterapia, 2009 Las moléculas HLA-G son antígenos HLA de clase I "no clásicos" del sistema principal de histocompatibilidad. Existen 6 isoformas del gen HLA-G que codifican 4 proteínas unidas a membrana (HLA-G1, HLA-G2, HLA-G3, HLA-G4) y 3 isoformas solubles (HLA-G5 ...
Dra. María E. Alfonso Valdés
doaj
Prognostic Value of HLA-G in Malignant Liver and Pancreas Lesions [PDF]
Iranian Journal of Immunology, 2018 Background: Human leukocyte antigen (HLA)-G is a nonclassical HLA class I molecule with modulatory effects on NK and T cells. Because HLA-G expression is frequently detected in different solid tumors, it may be involved in tumor immune evasion. Objective:
Parisa Khodabandeh Shahraki +4 more
doaj
The role of Qa-2, the functional homolog of HLA-G, in a Behcet's disease-like mouse model induced by the herpes virus simplex [PDF]
, 2010 BACKGROUND: It has been suggested that the HLA-G molecule is a genetic risk factor for Behcet's disease (BD). In this study, we evaluated the level of Qa-2, a murine nonclassical class I MHC molecule and possible functional homolog of HLA-G, to determine
Bunsoon Choi +6 more
core +2 more sources
Regulation of brain endothelial barrier function by microRNAs in health and neuroinflammation [PDF]
, 2016 Brain endothelial cells constitute the major cellular element of the highly specialized blood–brain barrier (BBB) and thereby contribute to CNS homeostasis by restricting entry of circulating leukocytes and blood-borne molecules into the CNS.
Arie Reijerkerk +6 more
core +3 more sources
HLA-G Expression Is an Independent Predictor for Improved Survival in High Grade Ovarian Carcinomas
Journal of Immunology Research, 2014 Aberrant expression of human leukocyte antigens (HLA) class I has prognostic importance in various cancers. Here, we evaluated the prognostic value of classical (A/B/C) and nonclassical (G/E) HLA expression in 169 high grade epithelial ovarian cancer ...
M. J. Rutten +6 more
doaj +1 more source
Controlling the immunological crosstalk during conception and pregnancy: HLA-G in reproduction
Frontiers in Immunology, 2014 In several years after its discovery in the placenta, the Human Leukocyte Antigen (HLA) class Ib protein, HLA-G, was not given much attention, nor was it assigned great importance. As time has unraveled, HLA-G has proven to have distinctive functions and
Line eLynge Nilsson +2 more
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