Non melanoma skin cancer pathogenesis overview [PDF]
, 2018 (1)Background: Non-melanoma skin cancer is the most frequently diagnosed cancer in humans. The process of skin carcinogenesis is still not fully understood.
Bottoni Ugo +3 more
core +1 more source
HLA-G:: ¿molécula inductora de inmunotolerancia? HLA-G molecule as inductor of immunotolerance
Revista Cubana de Hematología, Inmunología y Hemoterapia, 2009 Las moléculas HLA-G son antígenos HLA de clase I "no clásicos" del sistema principal de histocompatibilidad. Existen 6 isoformas del gen HLA-G que codifican 4 proteínas unidas a membrana (HLA-G1, HLA-G2, HLA-G3, HLA-G4) y 3 isoformas solubles (HLA-G5 ...
Dra. María E. Alfonso Valdés
doaj
Integrins and adhesion molecules: Gelatinase and oncofetal fibronectin secretion is dependent on integrin expression on human cytotrophoblasts [PDF]
, 2017 Collagenolytic activity of cytotrophoblasts is stimulated by glycoproteins of the extracellular matrix and since this stimulation can possibly occur through integrins, we measured the gelatinolytic activity of villous and extravillous cytotrophoblasts ...
Bischof, P., Campana, A., Haenggeli, L.
core
Evaluation of Soluble Human Leukocyte Antigen-G (sHLA-G) Isoforms and Regulatory T Cells in Relapsing-Remitting Multiple Sclerosis. [PDF]
, 2015 Soluble forms of nonclassical human leukocyte antigen (HLA)-G have recently been suggested as immunomodulatory factors in multiple sclerosis (MS). HLA-G inhibits the effecter function of T cells and natural killer (NK) cells.
Alsahebfosoul, Fereshteh. +5 more
core +2 more sources
Decidual Macrophages Are Significantly Increased in Spontaneous Miscarriages and Over-Express FasL [PDF]
, 2012 Decidual macrophages (DM) are the second most abundant population in the fetal-maternal interface. Their role has been so far identified as being local immuno-modulators favoring the maternal tolerance to the fetus.
Angioni +41 more
core +2 more sources
HLA-G Expression Is an Independent Predictor for Improved Survival in High Grade Ovarian Carcinomas
Journal of Immunology Research, 2014 Aberrant expression of human leukocyte antigens (HLA) class I has prognostic importance in various cancers. Here, we evaluated the prognostic value of classical (A/B/C) and nonclassical (G/E) HLA expression in 169 high grade epithelial ovarian cancer ...
M. J. Rutten +6 more
doaj +1 more source
Stem Cell Research, 2017 The human leukocyte antigen (HLA)-G gene seems to play a pivotal role in maternal tolerance to the fetus. Little is known about HLA-G expression and its molecular control during in vivo human embryogenesis.
A. Verloes +7 more
doaj +1 more source
Impaired Intracellular Transport and Cell Surface Expression of Nonpolymorphic HLA-E [PDF]
, 1992 The assembly of the classical, polymorphic major histocompatibility complex class I molecules in the endoplasmic reticulum requires the presence of peptide ligands and ~2-microglobulin (~2m). Formation of this trimolecular complex is a prerequisite for e~
Johnson, Judith P. +3 more
core +1 more source
The Dual Role of HLA-G in Cancer
Journal of Immunology Research, 2014 We here review the current data on the role of HLA-G in cancer based on recent findings of an unexpected antitumor activity of HLA-G in hematological malignancies.
Nathalie Rouas-Freiss +3 more
doaj +1 more source
Enhancing Natural Killer and CD8 + T Cell-Mediated Anticancer Cytotoxicity and Proliferation of CD8 + T Cells with HLA-E Monospecific Monoclonal Antibodies [PDF]
, 2019 Cytotoxic NK/CD8+ T cells interact with MHC-I ligands on tumor cells through either activating or inhibiting receptors. One of the inhibitory receptors is CD94/NKG2A.
Asgharzadeh, Shahab +3 more
core +1 more source