Prediction of HLA class II alleles using SNPs in an African population [PDF]
, 2012 BACKGROUND: Despite the importance of the human leukocyte antigen (HLA) gene locus in research and clinical practice, direct HLA typing is laborious and expensive.
Adeyemo, Adebowale +7 more
core +21 more sources
The role of HLA-DP mismatches and donor specific HLA-DP antibodies in kidney transplantation : a case series [PDF]
, 2021 BACKGROUND: The impact of HLA-DP mismatches on renal allograft outcome is still poorly understood and is suggested to be less than that of the other HLA loci.
Abramowicz, D +9 more
core +2 more sources
Diversity of HLA Class I and Class II blocks and conserved extended haplotypes in Lacandon Mayans. [PDF]
, 2020 Here we studied HLA blocks and haplotypes in a group of 218 Lacandon Maya Native American using a high-resolution next generation sequencing (NGS) method.
Aguilar-Vázquez, José Artemio +23 more
core +1 more source
Frequent HLA class I and DP sequence mismatches in serologically (HLA- A, HLA-B, HLA-DR) and molecularly (HLA-DRB1, HLA-DQA1, HLA-DQB1) HLA- identical unrelated bone marrow transplant pairs [PDF]
Blood, 1994 The rates of graft-versus-host disease (GVHD) and rejection are significantly higher among recipients of unrelated donor marrow (BM) than in recipients of marrow from HLA-identical siblings, even when donors and recipients are mixed lymphocyte culture (MLC) compatible and serologically and Dw identical.
P, Santamaria +7 more
openaire +3 more sources
Integrate CRISPR/Cas9 for protein expression of HLA-B*38:68Q via precise gene editing. [PDF]
, 2019 The determination of null- or low-expressed HLA alleles is clinically relevant in both hematopoietic stem cell transplantation and solid organ transplantation.
Reed, Elaine F +2 more
core +1 more source
Revista Paraguaya de Reumatología, 2021 Introducción: La enfermedad de Vogt-Koyanagi-Harada (VKH) es de etiología autoinmune y severa, se manifiesta con panuveítis bilateral y puede afectar sistema neuroauditivo y piel. La influencia de los factores genéticos en la expresión de VKH, ha quedado
Nelly Colmán +7 more
doaj +1 more source
E5 protein of human papillomavirus 16 downregulates HLA class I and interacts with the heavy chain via its first hydrophobic domai [PDF]
, 2006 Human papillomavirus type 16 E5 protein (HPV-16 E5) is expressed early in papillomavirus infection and is localised primarily in the cell Golgi apparatus (GA) and endoplasmic reticulum. E5 prevents transport of the major histocompatibility class I (MHC I;
Adam +30 more
core +1 more source
Expression analysis of HLA-E and NKG2A and NKG2C receptors points at a role for natural killer function in ankylosing spondylitis [PDF]
, 2018 Background. Ankylosing Spondylitis (AS) is a complex chronic inflammatory disease strongly associated with the majority of HLA-B27 alleles. HLA-E are non-classical MHC class I molecules that specifically interact with the natural killer receptors NKG2A ...
Angioni, Mm +12 more
core +1 more source
Diagnostics, 2020 Genetic variability defends us against pathogen-driven antigens; human leucocyte antigens (HLA) is the immunological system in charge of this work. The Mexican mestizo population arises mainly from the mixture of three founder populations; Amerindian ...
Alma D. Del Angel-Pablo +6 more
doaj +1 more source
Indirect Scapholunate Ligament Repair: All Arthroscopic
Arthroscopy Techniques, 2018 The arthroscopic technique most frequently used in acute scapholunate instability is reduction and fixation with Kirschner wires. To repair the injured ligament, open surgery and dorsal capsular plication are recommended, but this procedure has the risk ...
David Bustamante Suárez de Puga, M.D. +6 more
doaj +1 more source