In Silico Derivation of HLA-Specific Alloreactivity Potential from Whole Exome Sequencing of Stem Cell Transplant Donors and Recipients: Understanding the Quantitative Immuno-biology of Allogeneic Transplantation [PDF]
Frontiers in Immunology 2014. 5:529, 2014 Donor T cell mediated graft vs. host effects may result from the aggregate alloreactivity to minor histocompatibility antigens (mHA) presented by the HLA in each donor-recipient pair (DRP) undergoing stem cell transplantation (SCT). Whole exome sequencing has demonstrated extensive nucleotide sequence variation in HLA-matched DRP. Non-synonymous single
Batalo, Michael +14 more
arxiv +5 more sources
Prediction of HLA class II alleles using SNPs in an African population [PDF]
, 2012 BACKGROUND: Despite the importance of the human leukocyte antigen (HLA) gene locus in research and clinical practice, direct HLA typing is laborious and expensive.
Adeyemo, Adebowale +7 more
core +25 more sources
Developing a dementia inclusive hospital environment using an Integrated Care Pathway design: research protocol [PDF]
PeerJ, 2021 People with dementia occupy 25% of the hospital beds. When they are admitted to hospitals their cognitive impairment is not considered in most of the cases. Some European and North American countries already have experience of implementing national plans
Jorge Riquelme-Galindo +1 more
doaj +2 more sources
The role of HLA-DP mismatches and donor specific HLA-DP antibodies in kidney transplantation : a case series [PDF]
, 2021 BACKGROUND: The impact of HLA-DP mismatches on renal allograft outcome is still poorly understood and is suggested to be less than that of the other HLA loci.
Abramowicz, D +9 more
core +2 more sources
Diagnostic de la Maladie Cœliaque : Nouveaux paradigmes [PDF]
Batna Journal of Medical Sciences, 2021 La Maladie Cœliaque (MC) est définie comme une entéropathie chronique avec atrophie villositaire secondaire à une réponse immunitaire inappropriée de la muqueuse intestinale à la gliadine du blé et aux prolamines apparentées, survenant chez des ...
Nada Boutrid +3 more
doaj +1 more source
Intraosseous Squamous Cell Carcinoma Associated with Denosumab-Induced Osteonecrosis of the Jaw
Applied Sciences, 2021 Medication-related osteonecrosis of the jaw (MRONJ) has been associated with the use of different drugs administered in the treatment of malignant neoplasms or metastases and in antiresorptive therapies. Since 2010, denosumab, a monoclonal antibody whose
Sandra Bacián Martínez +13 more
doaj +1 more source
Comprehensive Analysis of the HLA Class I and the HLA class II Alleles in Patients with Takayasu Arteritis: Relationship with Clinical Patterns and Prognosis [PDF]
Iranian Journal of Immunology, 2021 Background: Takayasu arteritis (TA) is a systemic vasculitis, affecting mainly the aorta and its branches. Objective: To analyze the HLA class I and class II alleles in patients with TA and explore their relationship with clinical and demographic ...
Maja Stojanovic +9 more
doaj +1 more source
Docencia de la Medicina Intensiva. Aspectos bioéticos
Revista de Bioética y Derecho, 2020 Cualquier acto médico presenta siempre una doble vertiente, técnica y moral. La bioética, surge como herramienta clave para poder conjugar ambos aspectos en la toma diaria de decisiones médicas.
Samuel González López +1 more
doaj +1 more source
Role of the Host Genetic Susceptibility to 2009 Pandemic Influenza A H1N1
Viruses, 2021 Influenza A virus (IAV) is the most common infectious agent in humans, and infects approximately 10–20% of the world’s population, resulting in 3–5 million hospitalizations per year.
Gloria Pérez-Rubio +5 more
doaj +1 more source
BMC Immunology, 2022 Aim To investigate the association of human leukocyte antigen (HLA)-DRB1 alleles and the variations of polymorphic amino acid changes in DRβ1 chain in Shaanxi Han population with Occult hepatitis B infection (OBI).
Tianju Wang +5 more
doaj +1 more source