Mediators of Inflammation, 2006 Background. HLA genes play a role in the predisposition of several diseases. The aim was to analyze the prevalence of HLA class I phenotypes and HLA-DRB1* genotype in patients with CIU associated with ASA and NSAIDs hypersensitivity (AICU). Methods.
Maria Luisa Pacor +9 more
doaj +1 more source
The Role of HLA Antigens and Steroid Dose on the Course of COVID-19 of Patients After Kidney Transplantation. [PDF]
Front Med (Lausanne), 2021 Dedinská I +6 more
europepmc +1 more source
Whole Exome Sequencing to Estimate Alloreactivity Potential Between Donors and Recipients in Stem Cell Transplantation [PDF]
arXiv, 2014 Whole exome sequencing was performed on HLA-matched stem cell donors and transplant recipients to measure sequence variation contributing to minor histocompatibility antigen differences between the two. A large number of nonsynonymous single nucleotide polymorphisms were identified in each of the nine unique donor-recipient pairs tested. This variation
arxiv
The relationship between human leukocyte antigens (HLA) and renal cell carcinoma
Biomolecules & Biomedicine, 2010 Etiologies of Renal Cell Carcinoma (RCC) are not clear despite of the fact that many risk factors have been suggested. Especially in high stages RCC can affect the immune system in various ways.
Erkan Yılmaz +7 more
doaj +1 more source
Comparison of amino acid sequences of two human histocompatibility antigens, HLA-A2 and HLA-B7: location of putative alloantigenic sites. [PDF]
, 1979 Harry T. Orr +4 more
openalex +1 more source
HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome
Nature Communications, 2018 Human leukocyte antigens (HLA) are multi-allelic and polymorphic genes that present antigens to immune cells for inducing protective immunity. Here, using systems biology and structural approaches, the authors show that micropolymorphism of three HLA has
Patricia T. Illing +13 more
doaj +1 more source
Genetic basis of rheumatoid disease: HLA antigens, disease manifestations, and toxic reactions to drugs. [PDF]
, 1978 G S Panayi, P H Wooley, J. R. Batchelor
openalex +1 more source
Affinity Discrimination in B cells in Response to Membrane Antigen Requires Kinetic Proofreading [PDF]
arXiv, 2010 B cells signaling in response to antigen is proportional to antigen affinity, a process known as affinity discrimination. Recent research suggests that B cells can acquire antigen in membrane-bound form on the surface of antigen-presenting cells (APCs), with signaling being initiated within a few seconds of B cell/APC contact.
arxiv
Human histocompatibility determinants and virus antigens: effect of measles virus infection on HLA expression. [PDF]
, 1977 Martin V. Haspel +3 more
openalex +1 more source
Integrating influenza antigenic dynamics with molecular evolution [PDF]
arXiv, 2013 Influenza viruses undergo continual antigenic evolution allowing mutant viruses to evade host immunity acquired to previous virus strains. Antigenic phenotype is often assessed through pairwise measurement of cross-reactivity between influenza strains using the hemagglutination inhibition (HI) assay.
arxiv