Results 91 to 100 of about 195,520 (337)

Identification of HLA Class I Misreads/Dropouts Using Serological Typing, in Comparison with DNA-based Typing

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2016
Serology and DNA techniques are employed for Human Leukocyte Antigen (HLA) typing in different transplant centers. Results may not always correlate well and may need retyping with different technique.
Hamid Nawaz Tipu   +2 more
doaj  

HLA typing in Taiwanese patients with oral squamous cell carcinoma

open access: yesJournal of Dental Sciences, 2014
Background/purpose: The human leukocyte antigen (HLA) system, which plays a vital role in immunity, is the most polymorphic gene complex found in the human genome. This study investigated HLA-related alleles and haplotypes in Taiwanese patients with oral
Chia-Chun Lu   +4 more
doaj   +1 more source

The Role of HLA Antigens and Steroid Dose on the Course of COVID-19 of Patients After Kidney Transplantation. [PDF]

open access: yesFront Med (Lausanne), 2021
Dedinská I   +6 more
europepmc   +1 more source

Determining the Quantitative Principles of T Cell Response to Antigenic Disparity in Stem Cell Transplantation [PDF]

open access: yes, 2018
Alloreactivity compromising clinical outcomes in stem cell transplantation is observed despite HLA matching of donors and recipients. This has its origin in the variation between the exomes of the two, which provides the basis for minor ...
AbdulRazzaq, Badar   +17 more
core   +1 more source

Safety and Efficacy of Adoptive Transfer of Stem Cell Memory Enriched Virus Specific T Cells against CMV and EBV

open access: yesAdvanced Science, EarlyView.
This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao   +13 more
wiley   +1 more source

Genetic marker in juvenile diabetic retinopathy

open access: yesIndian Journal of Ophthalmology, 1989
Thirty five patients with insulin dependent diabetes mellitus (IDDM) were investigated for development of retinal microangiopathy by fluorescein angiography. HLA typing (A,B.C antigens) was done as a genetic marker. There was no statistically significant
Khosla P   +4 more
doaj  

Engaging the Immune Response to Normalize the Tumor Microenvironment [PDF]

open access: yes, 2013
Solid tumors exist as heterogeneous populations comprised not only of malignant cells, but various other cell types, including cells that make up the vasculature, that can strongly influence tumorgenicity.
Sabins, Nina, Storkus, Walter
core  

Type I Interferon Pathway Activation Disrupts Monocyte Maturation and Enhances Immune Evasion in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
This study shows that monocytes in multiple myeloma display an excessive interferon response, leading to transcriptional reprogramming and altered differentiation. Using single‐cell sequencing, coculture experiments, and patient samples before and after therapy, the authors demonstrate that induction treatment reduces this interferon response ...
Jian Cui   +18 more
wiley   +1 more source

Identification of Two Novel HLA-A∗0201-Restricted CTL Epitopes Derived from MAGE-A4

open access: yesClinical and Developmental Immunology, 2010
MAGE-A antigens belong to cancer/testis (CT) antigens that are expressed in tumors but not in normal tissues except testis and placenta. MAGE-A antigens and their epitope peptides have been used in tumor immunotherapy trials.
Zheng-Cai Jia   +7 more
doaj   +1 more source

Intraoperative blood transfusions in highly alloimmunized patients undergoing orthotopic liver transplantation. [PDF]

open access: yes, 1989
Intraoperative blood requirements were analyzed in patients undergoing primary orthotopic liver transplantation and divided into two groups on the basis of panel reactive antibody of pretransplant serum measured by lymphocytotoxicity testing.
Duquesnoy, RJ   +5 more
core   +1 more source

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