Results 121 to 130 of about 24,724 (214)
Most knowledge of hemophagocytic syndromes (HPSs) including hemophagocytic lymphohistiocytosis (HLH) is derived from pediatric studies; literature on adult HPS/HLH predominantly consists of small retrospective studies with clinical and methodological ...
Chen, Luke Y. C. +4 more
core +1 more source
Abstract In recent years, demand for human‐based in vitro models has grown substantially. In this regard, human secondary lymphoid organ (SLO)‐derived ex vivo immune organoids are gaining recognition, as they provide a platform for studying highly differentiated, tissue‐specific immune cell subsets found in SLOs, such as lymph nodes, tonsils, or spleen.
Maximilian Moll +3 more
wiley +1 more source
Effect of FLX on intracellular cAMP response of MLTC-1 cells to hLH or FSK/sub-hLH.
(A), (C) Real-time recording of luminescence under stimulation of MLTC-1 cells by hLH and FSK/sub-hLH in the presence of 0 to 100μM FLX. (B), (D) Dose-dependent effects of FLX on hLH and FSK/sub-hLH responses respectively, determined by the Area Under ...
Danièle Klett (252303) +3 more
core +1 more source
Ligand Redox Noninnocence in Bis(phosphinimine) Diarylamido Pincer Complexes of Nickel
The oxidative noninnocence of a bis(phosphinimine) ligand featuring a diarylamido backbone was investigated for several nickel complexes. Radical/charge delocalization across the aromatic backbone plays an important role in the stabilization of the diarylaminyl and putative diarylnitrenium complexes.
Xiujing Xing +8 more
wiley +1 more source
BackgroundEmapalumab, an interferon-γ (interferon-gamma)–blocking monoclonal antibody, has emerged as a targeted therapy for refractory hemophagocytic lymphohistiocytosis (HLH).
Abdulrahman F. Al-Mashdali +7 more
doaj +1 more source
A) Functional annotation and distribution of HLH-29 targets as predicted by DAVID analysis. Brackets indicate the number of target genes in each cluster.
Gaolin Zheng Milledge (393588) +4 more
core +1 more source
Therapeutic Plasma Exchange in Pediatric Patients: A Multi‐Institutional Landscape Analysis
ABSTRACT Pediatric evidence for therapeutic plasma exchange (TPE) is largely small, single‐center cohorts; there is no prior large‐scale age‐stratified outcomes assessment. Using the TriNetX US Collaborative Network, we identified 3744 patients ≤ 17 years old undergoing an index TPE procedure, stratified into four age groups (≤ 1, 2–5, 6–12, and 13–17 ...
Caitlin Raymond
wiley +1 more source
Haemophagocytic lymphohistiocytosis (HLH) affects patients across all age groups and can be classified as either primary HLH (P-HLH) or secondary HLH (S-HLH).
Catarina Pestana Santos +3 more
doaj +1 more source
ABSTRACT Lymphoma is a rare complication of X‐linked severe combined immunodeficiency (X‐SCID) caused by IL2RG deficiency. We report an infant with IL2RG‐SCID who developed diffuse large B‐cell lymphoma (DLBCL) during pretransplant evaluation. A male infant with T−B+ SCID was diagnosed at 1 month of age and referred for hematopoietic stem cell ...
Burcu Sarıgül Cimi +15 more
wiley +1 more source
Tiankuo Gao, Chun Yang, Yingxin Zhu, Junling Hu, Chen Gong, Yini Wang, Yue SongDepartment of Hematology, Capital Medical University Affiliated Beijing Anzhen Hospital, Beijing, 100029, People’s Republic of ChinaCorrespondence: Yini Wang; Yue Song, Email ...
Gao T +6 more
doaj

