Results 131 to 140 of about 24,724 (214)

HLH Syndrome in a Community Hospital: The Challenge of an Early Diagnosis

Yuval Wagner,1,2 Dganit Adam,2,3 Galit Pomeranz Engelberg,1,2 Avishalom Pomeranz,1,2,* Yoav H Messinger4,* 1Pediatric Department, Meir Medical Center, Kfar Saba, Israel; 2Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel ...
Wagner Y, Pomeranz Engelberg G, Adam D, Pomeranz A, Messinger YH   +4 more
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Diagnostic criteria for HLH used in the HLH-2004 trial^*.

, 2019
The diagnosis of HLH is established when 5 of the 8 criteria listed below are fulfilled.
Jacqueline De Gottardi (8201541), Alicia Rovo (121163), Anne Angelillo-Scherrer (591364), Matteo Montani (8201544), Annalisa Berzigotti (387331)   +4 more
core   +1 more source

The Mycorrhizal Fungal Species Funneliformis mosseae Reshapes Rhizosphere Microbial Metabolic Pathways of Soybeans Under Tetracycline Stress

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
The presence of residual antibiotics (tetracycline) poses a threat to food safety in the black soils of northeastern China and a mycorrhizal fungal species Funneliformis mosseae could mitigate the negative effects. This study tracked the changes in soybeans' rhizospheric microbial profiles and the associated metabolites during the bioremediation ...
Chao Yang, Baiyan Cai, Harry Lye Hin Chong, Juan Li, Linghui Li, Jean Wan Hong Yong, Khim Phin Chong   +6 more
wiley   +1 more source

Ginsenoside Rg3 Promotes Healthy Aging Through Phosphoinositide‐Associated Lysosomal Regulation in Caenorhabditis elegans

Aging Cell, Volume 25, Issue 10, October 2026.
Ginsenoside Rg3 shifts neuronal phosphoinositide reporter signatures toward increased PI(4)P and reduced PI(3)P signals. These changes are coupled to TORC1 suppression and HLH‐30/TFEB activation, alongside restored autophagic flux and lysosomal competence, preserved neuronal proteostasis, and extended lifespan in Caenorhabditis elegans.
Haiyang Yu, Shiming Li, Yongsheng Chen, Yaoyong Zeng, Junbu Li, Yuxin Guo, Wanxiang Zhang, Lizhu Zhang, Longnong You, Kuncan Chen, Jinhong Wu, Dan Gan, Jiane‐Kang Liu, Lingjun Zheng   +13 more
wiley   +1 more source

MTR4: A Conserved Youth Factor for Vascular Endothelium

Aging Cell, Volume 25, Issue 10, October 2026.
Senescence‐induced SYVN1 degrades MTR4 via K638 ubiquitination. MTR4 loss disrupts its binding to BUB3 and destabilizes BUB3, diminishing BUBR1 and driving endothelial senescence. MTR4 restoration reverses vascular aging in mice and extends C. elegans lifespan.
Zhenyuan Guo, Zhiqiang Chen, Jiaqi Sun, Xiaojun Zhou, Chengzhi Ni, Yuxiang Zhang, Pengfei Qiang, Lu Zhang   +7 more
wiley   +1 more source

The association between inborn errors of immunity and Hodgkin lymphoma—A register‐based case–control study in Sweden

British Journal of Haematology, Volume 209, Issue 4, Page 1629-1637, October 2026.
Summary Immune dysfunction is implicated in the aetiology of Hodgkin lymphoma (HL), but the association between inborn errors of immunity (IEI) and HL remains poorly understood. We conducted a retrospective, register‐based case–control study in Sweden over five decades to investigate the relationship between IEI and HL. Individuals diagnosed with HL in
Agnes Winsa, Ingemar Lagerlöf, Fredrik Ellin, Mats Fredriksson, Åsa Nilsdotter‐Augustinsson, Marcus Bendtsen, Jörg Cammenga, Sofia Nyström   +7 more
wiley   +1 more source

INtraVESical immunoTherapy (INVEST) prior to radical cystectomy for bladder cancer: trial protocol

BJU International, Volume 138, Issue 4, Page 607-619, October 2026.
Background High‐risk non‐muscle‐invasive bladder cancer (HRNMIBC) has a variable prognosis, managed predominantly by local surgical resection and intravesical Bacillus Calmette–Guérin (BCG), or radical cystectomy (RC). Current treatments are poorly tolerated, have supply limitations and often fail to control the disease.
Ruby Lister‐Whelan, Ethan Senior, Jessica Kendall, Jamie B. Oughton, Fiona Collinson, Jon Griffin, Rachel Hubbard, Steven Kennish, Aidan Noon, Derek J. Rosario, Irbaz B. Riaz, Julie Telliez, James W. F. Catto, Syed A. Hussain   +13 more
wiley   +1 more source

STAGE IV EPSTEIN-BARR VIRUS (EBV) CLASSIC HODGKIN LYMPHOMA (CHL) WITH HEPATIC INVOLVEMENT MEETING CRITERIA FOR HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS (HLH) AT STANFORD: CLOSE MIMIC VERSUS TRUE HLH?

, 2019
STAGE IV EPSTEIN-BARR VIRUS (EBV) CLASSIC HODGKIN LYMPHOMA (CHL) WITH HEPATIC INVOLVEMENT MEETING CRITERIA FOR HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS (HLH) AT STANFORD: CLOSE MIMIC VERSUS TRUE ...
Beth Martin (5661031), Michael Jeng (21023705), Eric Lau (15903800), Haley Weiner (21023681)   +3 more
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Impact of Albuminuria‐Lowering Treatments on Cardiovascular Predictive Ceramides in Diabetes: Post Hoc Analysis of the ROTATE Trials

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9346-9355, October 2026.
ABSTRACT Aim Cardiovascular disease (CVD) is the leading cause of mortality in individuals with diabetes. Diabetic kidney disease, closely related to CVD risk, is prevalent in up to 40% of this population. Emerging evidence suggests ceramide lipids as accurate biomarkers for CVD.
Kristina Pigsborg, Simon Maria Kienle, Asger Wretlind, Viktor Rotbain Curovic, Martin Bæk Blond, Hiddo J. L. Heerspink, Tine Willum Hansen, Frederik Persson, Karolina Sulek, Cristina Legido‐Quigley, Peter Rossing   +10 more
wiley   +1 more source

Functional Analysis of HLH-3, a bHLH Achaete/Scute Protein, in HSN Maturation

, 2017
The basic helix loop helix protein, HLH-3, is a member of the Achaete/Scute family in C. elegans that is required for normal egg-laying behavior. hlh-3 null mutants have an egg-laying defective (Egl) phenotype.
Saleel Raut (7963574)
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